KRTAP10-9 and GSTP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-9	GSTP1
Gene Name		keratin associated protein 10-9	glutathione S-transferase pi 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Extracellular Space Intracellular Nucleus Cytoplasm Mitochondrion Cytosol Plasma Membrane Vesicle Extracellular Vesicular Exosome TRAF2-GSTP1 Complex
	Molecular Function		Glutathione Transferase Activity Protein Binding JUN Kinase Binding Kinase Regulator Activity S-nitrosoglutathione Binding Dinitrosyl-iron Complex Binding Nitric Oxide Binding
	Biological Process		Response To Reactive Oxygen Species Negative Regulation Of Acute Inflammatory Response Negative Regulation Of Protein Kinase Activity Glutathione Metabolic Process Xenobiotic Metabolic Process Central Nervous System Development Negative Regulation Of Biosynthetic Process Negative Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Negative Regulation Of Interleukin-1 Beta Production Negative Regulation Of Tumor Necrosis Factor Production Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Superoxide Anion Generation Common Myeloid Progenitor Cell Proliferation Nitric Oxide Storage Negative Regulation Of Apoptotic Process Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of MAP Kinase Activity Negative Regulation Of MAPK Cascade Negative Regulation Of JUN Kinase Activity Small Molecule Metabolic Process Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Nitric-oxide Synthase Biosynthetic Process Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Leukocyte Proliferation Cellular Response To Lipopolysaccharide Negative Regulation Of Monocyte Chemotactic Protein-1 Production Glutathione Derivative Biosynthetic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD) Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD) Defective TPMT causes Thiopurine S-methyltransferase deficiency (TPMT deficiency) Defective MAT1A causes Methionine adenosyltransferase deficiency (MATD) Detoxification of Reactive Oxygen Species Defective UGT1A4 causes hyperbilirubinemia Glutathione conjugation Metabolic disorders of biological oxidation enzymes Phase II conjugation Defective UGT1A1 causes hyperbilirubinemia Defective SLC35D1 causes Schneckenbecken dysplasia (SCHBCKD) Biological oxidations Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD) Defective GGT1 causes Glutathionuria (GLUTH) Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)
Drugs			Glutathione Clomipramine (9r,10r)-9-(S-Glutathionyl)-10-Hydroxy-9,10-Dihydrophenanthrene S-Hydroxycysteine Cibacron Blue Glutathione Sulfonic Acid S-(P-Nitrobenzyl)Glutathione 2-(N-Morpholino)-Ethanesulfonic Acid Glycerol S-Hexylglutathione Carboxymethylenecysteine S-NONYL-CYSTEINE S-(4-BROMOBENZYL)CYSTEINE
Diseases
GWAS
Protein-Protein Interactions		163 interactors: ADAMTSL4 AES ALDH3B1 ALPI ARFGAP1 ATXN7L1 AVPI1 BCL6B C10orf62 C11orf87 C16orf59 C19orf57 C19orf66 C5orf60 C9orf9 CARKD CATIP CATSPER1 CBX2 CCDC26 CD300LG CDKL3 CHIC2 CHRD CHRNG CKS1B CLK4 CNNM3 CRCT1 CREB5 CST9L CXCL16 DHX57 DMRT3 DOCK2 EIF4E2 FAM124B FAM161A FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GATA2 GLIDR GLP1R GLRX3 GNE GPATCH2L GSTP1 HBG1 HBZ HCK HOXA1 HOXB9 HPCAL1 HSD3B7 IGSF8 INPP5D IQUB ITGB5 KAT5 KIF9 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LUZP4 MAB21L3 MAPKBP1 MED30 MEOX2 MOBP MT1DP MXI1 NOTCH2NL NPBWR2 NPDC1 NPPB NR1D2 NUFIP2 OTX1 PGAP2 PGLS PIN1 PLSCR1 PRKAB2 PRPF31 PTGER3 PVR PVRL3 RAB7A RHNO1 RSPO2 SCARB1 SCNM1 SLC23A1 SLC6A20 SMARCE1 SMCP SPATA3 SPATA8 SPG7 SPRY1 SPRY2 STK16 TBC1D16 TBC1D23 TGOLN2 THAP10 TNFRSF6B TNP2 TRIM41 TRIM42 TXNDC5 TYMSOS TYRO3 UTP23 WNT11 WT1-AS XCL2 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF124 ZNF155 ZNF20 ZNF264 ZNF317 ZNF417 ZNF439 ZNF440 ZNF473 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF697 ZNF699 ZNF792 ZNF844 ZSCAN21 ZSCAN26	15 interactors: APPBP2 FANCC KRT31 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAPK8 MLH1 NOTCH2NL PNO1 PTN SCAF1 SUMO4 TGM2 TRAF2
Entrez ID		386676	2950
HPRD ID		11195	00614
Ensembl ID		ENSG00000221837	ENSG00000084207
Uniprot IDs		P60411	P09211
PDB IDs			10GS 11GS 12GS 13GS 14GS 16GS 17GS 18GS 19GS 1AQV 1AQW 1AQX 1EOG 1EOH 1GSS 1KBN 1LBK 1MD3 1MD4 1PGT 1PX6 1PX7 1ZGN 20GS 22GS 2A2R 2A2S 2GSS 2J9H 2PGT 3CSH 3CSI 3CSJ 3DD3 3DGQ 3GSS 3GUS 3HJM 3HJO 3HKR 3IE3 3KM6 3KMN 3KMO 3N9J 3PGT 4GSS 4PGT 5GSS 6GSS 7GSS 8GSS 9GSS
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Keratinization Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Keratinocyte Differentiation Cellular Metabolic Process Epidermis Development Epidermal Cell Differentiation Lung Growth Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Phagocytosis Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Podosome Assembly Apoptotic Cell Clearance Penetration Of Zona Pellucida Organelle Disassembly Tissue Development Skin Development Epithelium Development Multicellular Organismal Development Bud Elongation Involved In Lung Branching Cellular Response To Lipid Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Inner Ear Morphogenesis Fertilization Negative Regulation Of ERBB Signaling Pathway Phagocytosis Anatomical Structure Development	Cellular Response To Nitric Oxide Cellular Response To Reactive Oxygen Species Response To Nitric Oxide Cellular Response To Reactive Nitrogen Species Response To Reactive Oxygen Species Cellular Response To Oxidative Stress Programmed Necrotic Cell Death Necrotic Cell Death TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Meiotic Spindle Midzone Assembly Meiotic Metaphase I Plate Congression Toll-like Receptor 4 Signaling Pathway Response To Oxidative Stress Protein Complex Assembly Negative Regulation Of Mitotic Recombination Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Response To Inorganic Substance Toll-like Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Mitotic Recombination Male Meiosis Chromosome Segregation Cellular Response To Inorganic Substance Activation Of Innate Immune Response Regulation Of Protein Binding Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death JUN Phosphorylation Positive Regulation Of Cell Death Positive Regulation Of Deacetylase Activity Salivary Gland Cavitation Negative Regulation Of Glial Cell Apoptotic Process Positive Regulation Of Innate Immune Response Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Determination Of Dorsal Identity Cellular Response To Stress Positive Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Calcium Ion Concentration Spindle Midzone Assembly Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Positive Regulation Of Protein Homodimerization Activity Resolution Of Meiotic Recombination Intermediates Regulation Of Innate Immune Response Germ Cell Development Peptidyl-lysine Modification Regulation Of Immunoglobulin Secretion Protein Homooligomerization
Tagcloud ?			abolished acetylcysteine acetyltransferase ap1 boxes chloramphenicol consensus construct detoxication division embryogenesis evolved gggaccctcc h2o2 immediately impairs inducer kappa localizes mad nac proliferating protect redox repression share transfection transferase
Tagcloud (Difference) ?			abolished acetylcysteine acetyltransferase ap1 boxes chloramphenicol consensus construct detoxication division embryogenesis evolved gggaccctcc h2o2 immediately impairs inducer kappa localizes mad nac proliferating protect redox repression share transfection transferase
Tagcloud (Intersection) ?