KRTAP10-9 and SPG7

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-9	SPG7
Gene Name		keratin associated protein 10-9	spastic paraplegia 7 (pure and complicated autosomal recessive)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Mitochondrion Integral Component Of Membrane Mitochondrial Membrane
	Molecular Function		Metalloendopeptidase Activity Protein Binding ATP Binding Peptidase Activity Zinc Ion Binding Unfolded Protein Binding
	Biological Process		Proteolysis Mitochondrion Organization Nervous System Development Anterograde Axon Cargo Transport
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		163 interactors: ADAMTSL4 AES ALDH3B1 ALPI ARFGAP1 ATXN7L1 AVPI1 BCL6B C10orf62 C11orf87 C16orf59 C19orf57 C19orf66 C5orf60 C9orf9 CARKD CATIP CATSPER1 CBX2 CCDC26 CD300LG CDKL3 CHIC2 CHRD CHRNG CKS1B CLK4 CNNM3 CRCT1 CREB5 CST9L CXCL16 DHX57 DMRT3 DOCK2 EIF4E2 FAM124B FAM161A FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GATA2 GLIDR GLP1R GLRX3 GNE GPATCH2L GSTP1 HBG1 HBZ HCK HOXA1 HOXB9 HPCAL1 HSD3B7 IGSF8 INPP5D IQUB ITGB5 KAT5 KIF9 KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP12-1 KRTAP26-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2A LCE2D LCE3C LCE3E LCE4A LUZP4 MAB21L3 MAPKBP1 MED30 MEOX2 MOBP MT1DP MXI1 NOTCH2NL NPBWR2 NPDC1 NPPB NR1D2 NUFIP2 OTX1 PGAP2 PGLS PIN1 PLSCR1 PRKAB2 PRPF31 PTGER3 PVR PVRL3 RAB7A RHNO1 RSPO2 SCARB1 SCNM1 SLC23A1 SLC6A20 SMARCE1 SMCP SPATA3 SPATA8 SPG7 SPRY1 SPRY2 STK16 TBC1D16 TBC1D23 TGOLN2 THAP10 TNFRSF6B TNP2 TRIM41 TRIM42 TXNDC5 TYMSOS TYRO3 UTP23 WNT11 WT1-AS XCL2 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF124 ZNF155 ZNF20 ZNF264 ZNF317 ZNF417 ZNF439 ZNF440 ZNF473 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF697 ZNF699 ZNF792 ZNF844 ZSCAN21 ZSCAN26	23 interactors: CCNDBP1 HNRNPK KHDRBS2 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP4-12 LRIF1 LZTS2 MAPK6 MDFI MTUS2 NOTCH2NL PLSCR1 PNMA1 PSME3 PSTPIP1 RALY RBPMS SPATS1 STAMBP TRIM28
Entrez ID		386676	6687
HPRD ID		11195	04149
Ensembl ID		ENSG00000221837	ENSG00000197912
Uniprot IDs		P60411	Q9UQ90
PDB IDs			2QZ4
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Biosynthetic Process Keratinization Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Cellular Process Keratinocyte Differentiation Cellular Metabolic Process Epidermis Development Epidermal Cell Differentiation Lung Growth Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Phagocytosis Regulation Of Transcription From RNA Polymerase II Promoter Developmental Process Regulation Of Neurotrophin TRK Receptor Signaling Pathway Regulation Of Podosome Assembly Apoptotic Cell Clearance Penetration Of Zona Pellucida Organelle Disassembly Tissue Development Skin Development Epithelium Development Multicellular Organismal Development Bud Elongation Involved In Lung Branching Cellular Response To Lipid Epithelial Tube Branching Involved In Lung Morphogenesis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Inner Ear Morphogenesis Fertilization Negative Regulation Of ERBB Signaling Pathway Phagocytosis Anatomical Structure Development	Regulation Of Protein Localization To Nucleus Regulation Of Protein Import Into Nucleus Negative Regulation Of Wnt Signaling Pathway Regulation Of Cellular Process Regulation Of Nucleocytoplasmic Transport Regulation Of Intracellular Protein Transport Gene Expression Regulation Of Wnt Signaling Pathway Negative Regulation Of Viral Process Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of DNA Demethylation Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Cycle Regulation Of Protein Localization Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Cytokinesis Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Embryonic Placenta Development Transcription, DNA-templated Inflammatory Response Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Intracellular Transport RNA Metabolic Process RNA Biosynthetic Process Convergent Extension Involved In Axis Elongation Regulation Of Genetic Imprinting Phosphatidylserine Biosynthetic Process DNA Methylation Involved In Embryo Development Regulation Of Cellular Localization Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Signal Transduction Regulation Of Viral Process Response To Stimulus Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Positive Regulation Of Intracellular Protein Transport RNA Processing Negative Regulation Of Signaling Regulation Of Signal Transduction Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Receptor Biosynthetic Process Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Spindle Midzone Assembly Placenta Development Positive Regulation Of Protein Metabolic Process Phospholipid Scrambling Regulation Of Protein Transport
Tagcloud ?			ablated accumulates axons biogenesis corticospinal defines exposes hereditary implication isoform knock lacks limbs lumen microsomal name owing paraplegia paraplegin performs proteases recessive resides retina retrograde spastic spasticity usage weakness
Tagcloud (Difference) ?			ablated accumulates axons biogenesis corticospinal defines exposes hereditary implication isoform knock lacks limbs lumen microsomal name owing paraplegia paraplegin performs proteases recessive resides retina retrograde spastic spasticity usage weakness
Tagcloud (Intersection) ?