MYPOP and KHDRBS3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYPOP	KHDRBS3
Description		Myb related transcription factor, partner of profilin	KH RNA binding domain containing, signal transduction associated 3
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Protein-containing Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding SH3 Domain Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome
Pathways			PTK6 Regulates Proteins Involved in RNA Processing
Drugs
Diseases
GWAS		Asthma ( 31959851)	Chronotype ( 30696823) Colorectal cancer ( 34062886) Disease progression in age-related macular degeneration ( 29346644) Polycystic ovary syndrome ( 25574032) Squamous cell lung carcinoma ( 28604730) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		42 interacting genes: AKAP8L BAG4 BBC3 CARD10 CHIC2 CIB4 CYSRT1 FHL3 HNRNPH1 HNRNPK HOXA1 KHDRBS3 KIFAP3 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP19-5 KRTAP19-6 KRTAP3-1 KRTAP5-6 MDFI MTUS2 NBPF19 NCK2 NECAB2 NOTCH2NLA PFN1 PFN2 PRDM14 PRR3 RBM3 RBMX RBMY1A1 RBPMS2 SAT1 SYNCRIP TGM1 TNS2 TRA2B	59 interacting genes: AQP1 BAHD1 CACNA1A CCDC187 CCDC33 CNNM3 CPSF7 DMRT3 DOCK2 FBXO7 FUS FXR1 HBZ HNRNPC HNRNPK HNRNPR INPP5D KHDRBS1 KHDRBS2 LMNTD2 LNX1 MARK4 MYPOP NCOA5 NELFB NUDT18 OGT PCDHB14 PPP1R13B PRMT1 PRPF31 PRR3 PSMA1 PSMF1 PTBP2 RASAL3 RASD1 RBBP6 RBM3 RBM7 RBMX RBMY1A1 RFC3 RPH3AL SGSM2 SIAH1 SNRPC SNX18 SRSF9 TSGA10IP TYK2 U2AF2 WWP2 YTHDC1 ZNF326 ZNF408 ZNF575 ZNF580 ZNF688
Entrez ID		339344	10656
HPRD ID		17352	10007
Ensembl ID		ENSG00000176182	ENSG00000131773
Uniprot IDs		Q86VE0	O75525
PDB IDs			5EL3 5ELR 5ELS 5ELT 5EMO
Enriched GO Terms of Interacting Partners?		Intermediate Filament Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Keratin Filament Spliceosomal Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Positive Regulation Of Actin Filament Polymerization RNA Binding Nucleic Acid Binding MRNA Processing Identical Protein Binding RNA Splicing MRNA Binding Positive Regulation Of Protein Polymerization Catalytic Step 2 Spliceosome MRNA Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Protein-containing Complex Assembly RNA Splicing, Via Transesterification Reactions RNA Processing Regulation Of Actin Filament Polymerization Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of MRNA Metabolic Process Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Actin Filament Bundle Assembly Protein Binding Adenyl-nucleotide Exchange Factor Activity Positive Regulation Of Supramolecular Fiber Organization Modification Of Postsynaptic Structure Positive Regulation Of Cytoskeleton Organization Negative Regulation Of MRNA Splicing, Via Spliceosome Modification Of Synaptic Structure Actin Monomer Binding Regulation Of Stress Fiber Assembly Ribonucleoprotein Complex Protein Domain Specific Binding Negative Regulation Of RNA Splicing Semicircular Canal Formation Spermidine Binding Negative Regulation Of MRNA Modification T Cell Apoptotic Process Positive Regulation Of Calcium-dependent Cell-cell Adhesion	Regulation Of RNA Splicing MRNA Processing Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome RNA Splicing Regulation Of MRNA Processing RNA Processing MRNA Binding RNA Binding Regulation Of MRNA Metabolic Process MRNA Metabolic Process Spliceosomal Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing Negative Regulation Of MRNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Regulation Of RNA Metabolic Process Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome MRNA Splice Site Recognition Nucleic Acid Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of RNA Splicing Negative Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Poly(U) RNA Binding Protein-RNA Complex Assembly MRNA Alternative Polyadenylation Nucleobase-containing Compound Metabolic Process Negative Regulation Of Metabolic Process Negative Regulation Of Gene Expression Commitment Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Nucleoplasm Positive Regulation Of NK T Cell Proliferation Positive Regulation Of Translation Catalytic Step 2 Spliceosome Protein-containing Complex Assembly Positive Regulation Of NK T Cell Activation Protein Binding
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