MYPOP and RBMX

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MYPOP	RBMX
Description		Myb related transcription factor, partner of profilin	RNA binding motif protein X-linked
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Euchromatin Extracellular Space Nucleus Nucleoplasm Spliceosomal Complex Membrane Protein-containing Complex Organelle Supraspliceosomal Complex Extracellular Exosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Nucleic Acid Binding Chromatin Binding RNA Binding MRNA Binding Protein Binding Protein Domain Specific Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription By RNA Polymerase II MRNA Processing Membrane Protein Ectodomain Proteolysis RNA Splicing Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of MRNA Splicing, Via Spliceosome Protein Homooligomerization Cellular Response To Interleukin-1
Pathways			mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA RHOBTB2 GTPase cycle RHOBTB1 GTPase cycle RND3 GTPase cycle RND2 GTPase cycle RND1 GTPase cycle
Drugs
Diseases
GWAS		Asthma ( 31959851)	Pediatric autoimmune diseases ( 26301688)
Interacting Genes		42 interacting genes: AKAP8L BAG4 BBC3 CARD10 CHIC2 CIB4 CYSRT1 FHL3 HNRNPH1 HNRNPK HOXA1 KHDRBS3 KIFAP3 KRT40 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP19-5 KRTAP19-6 KRTAP3-1 KRTAP5-6 MDFI MTUS2 NBPF19 NCK2 NECAB2 NOTCH2NLA PFN1 PFN2 PRDM14 PRR3 RBM3 RBMX RBMY1A1 RBPMS2 SAT1 SYNCRIP TGM1 TNS2 TRA2B	51 interacting genes: APOBEC3C CCDC33 CEBPA CIRBP CLK1 CLK3 CMTM6 CNNM3 CSNK2A1 FOXP1 FXR2 HNRNPK IL7R ITSN2 JAK2 KHDRBS2 KHDRBS3 LINC01232 LNX1 MAGOHB MYPOP NABP1 NEIL3 NFE2L2 NXF1 NYX OGT PCBP2 PCDHB14 PRPF31 PRR3 PSMF1 PWARSN RAMAC RBM3 RBM7 RBMY1A1 RBMY1E RBMY1F RBMY1J ROBO3 SF1 SNRPA SOCS3 SORBS3 SREK1 SRPK2 STAT5A TRA2B XRN1 ZNF490
Entrez ID		339344	27316
HPRD ID		17352	02186
Ensembl ID		ENSG00000176182	ENSG00000147274
Uniprot IDs		Q86VE0	P38159
PDB IDs			2MB0 2MKS
Enriched GO Terms of Interacting Partners?		Intermediate Filament Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Regulation Of MRNA Metabolic Process Keratin Filament Spliceosomal Complex Positive Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of RNA Splicing Positive Regulation Of Actin Filament Polymerization RNA Binding Nucleic Acid Binding MRNA Processing Identical Protein Binding RNA Splicing MRNA Binding Positive Regulation Of Protein Polymerization Catalytic Step 2 Spliceosome MRNA Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process Positive Regulation Of Protein-containing Complex Assembly RNA Splicing, Via Transesterification Reactions RNA Processing Regulation Of Actin Filament Polymerization Positive Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of MRNA Metabolic Process Regulation Of Thymocyte Apoptotic Process Positive Regulation Of Actin Filament Bundle Assembly Protein Binding Adenyl-nucleotide Exchange Factor Activity Positive Regulation Of Supramolecular Fiber Organization Modification Of Postsynaptic Structure Positive Regulation Of Cytoskeleton Organization Negative Regulation Of MRNA Splicing, Via Spliceosome Modification Of Synaptic Structure Actin Monomer Binding Regulation Of Stress Fiber Assembly Ribonucleoprotein Complex Protein Domain Specific Binding Negative Regulation Of RNA Splicing Semicircular Canal Formation Spermidine Binding Negative Regulation Of MRNA Modification T Cell Apoptotic Process Positive Regulation Of Calcium-dependent Cell-cell Adhesion	Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Nucleic Acid Binding Spliceosomal Complex RNA Binding Regulation Of MRNA Metabolic Process MRNA Metabolic Process RNA Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Processing Positive Regulation Of RNA Splicing Nucleic Acid Metabolic Process RNA Processing Positive Regulation Of MRNA Metabolic Process RNA Splicing Nucleobase-containing Compound Metabolic Process Positive Regulation Of Gene Expression Nucleoplasm Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of RNA Metabolic Process Nucleus Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of Macromolecule Metabolic Process Interleukin-6-mediated Signaling Pathway MRNA Splicing, Via Spliceosome Identical Protein Binding RNA Splicing, Via Transesterification Reactions Regulation Of Metabolic Process Interleukin-5-mediated Signaling Pathway Cytoplasmic Stress Granule Thrombopoietin-mediated Signaling Pathway Interleukin-3-mediated Signaling Pathway Interleukin-7-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Biosynthetic Process Response To Tumor Necrosis Factor Mammary Gland Epithelium Development Protein Domain Specific Binding Positive Regulation Of RNA Metabolic Process Negative Regulation Of Leukocyte Apoptotic Process Negative Regulation Of Proteasomal Protein Catabolic Process Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cell Surface Receptor Signaling Pathway Via JAK-STAT
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