PRSS23 and EFNA3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PRSS23	EFNA3
Gene Name		protease, serine, 23	ephrin-A3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Extracellular Vesicular Exosome	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Anchored Component Of Membrane
	Molecular Function	Serine-type Endopeptidase Activity	Transmembrane-ephrin Receptor Activity Ephrin Receptor Binding
	Biological Process	Proteolysis	Cell-cell Signaling Axon Guidance Ephrin Receptor Signaling Pathway
Pathways			EPHA-mediated growth cone collapse EPH-ephrin mediated repulsion of cells Axon guidance EPH-Ephrin signaling
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		25 interactors: ACTG1 APP B2M CHP1 EFNA3 FXR1 GRK6 HSPA4 MAPK8IP2 NCAPD3 NIPBL NOC4L ODF2L PDDC1 PDPK1 PHF23 PPIA RACGAP1 RECQL4 RPL4P5 SHMT1 SLC25A6 TCF12 TMEM222 TRAPPC4	9 interactors: EPHA2 EPHA3 EPHA4 EPHA5 EPHA7 KRTAP10-3 MEOX2 NOTCH2NL PRSS23
Entrez ID		11098	1944
HPRD ID		07149	03225
Ensembl ID		ENSG00000150687	ENSG00000143590
Uniprot IDs		B4E2J3 O95084	B7ZAD3 P52797
PDB IDs
Enriched GO Terms of Interacting Partners?		Platelet Activation Blood Coagulation Hemostasis Cell Differentiation Cellular Component Assembly Regulation Of Body Fluid Levels Organelle Organization Wound Healing Multicellular Organismal Development Generation Of Neurons Cell Activation Dendrite Development System Development Response To Stress Response To Wounding Neurogenesis Mating Behavior Nervous System Development Regulation Of Protein Localization Response To Stimulus Neuron Projection Development Cell Development Developmental Process Cytokinesis, Initiation Of Separation Actomyosin Contractile Ring Assembly Uncoating Of Virus Mating Anatomical Structure Development Neuron Development Retina Homeostasis Movement Of Cell Or Subcellular Component Cell Morphogenesis Involved In Neuron Differentiation Protein Targeting To Mitochondrion Protein Complex Assembly Regulation Of Cellular Localization Immune System Process Platelet Degranulation Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity Synaptic Growth At Neuromuscular Junction Active Induction Of Host Immune Response By Virus Mitotic Sister Chromatid Segregation Protein Localization To Mitochondrion Protein Folding Cognition Neuron Projection Morphogenesis Positive Regulation Of Cellular Protein Metabolic Process Neuron Differentiation Mitotic Nuclear Division Sister Chromatid Segregation Regulation Of Establishment Of Protein Localization	Ephrin Receptor Signaling Pathway Peptidyl-tyrosine Phosphorylation Axon Guidance Fasciculation Of Motor Neuron Axon Fasciculation Of Sensory Neuron Axon Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Rho GTPase Activity Cell Morphogenesis Involved In Differentiation Neuron Projection Development Regulation Of Rho Protein Signal Transduction Cell Projection Morphogenesis Cell Part Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Peptidyl-amino Acid Modification Neuron Development Cell Morphogenesis Neuron Differentiation Cell Projection Organization Regulation Of Rac GTPase Activity Regulation Of Ras GTPase Activity Locomotion Axonal Fasciculation Protein Phosphorylation Anatomical Structure Morphogenesis Regulation Of Ras Protein Signal Transduction Movement Of Cell Or Subcellular Component Regulation Of Rac Protein Signal Transduction Neuron Recognition Generation Of Neurons Regulation Of Small GTPase Mediated Signal Transduction Regulation Of GTPase Activity Neurogenesis Multicellular Organismal Development Regulation Of Intracellular Signal Transduction Cell Surface Receptor Signaling Pathway Cell Development Response To External Stimulus Phosphorylation Cell Differentiation Developmental Process Positive Regulation Of Rho Guanyl-nucleotide Exchange Factor Activity Notochord Cell Development Nervous System Development Regulation Of Cell Projection Organization Regulation Of Catalytic Activity
Tagcloud ?			a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efnb2 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53
Tagcloud (Difference) ?			a2780 a2780mtp53 adamts1 affymetrix angiogenesis angiogenic angiopoietin arrays b4 confirmation constituents ecm efnb2 endoglin ephrin exploratory fgf20 hypoxic integral ionizing metalloproteinase microenvironment mmp10 mtp53 tp53 u133a upregulated vegfa wttp53
Tagcloud (Intersection) ?