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PRSS23 and HSPA4
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PRSS23
HSPA4
Gene Name
protease, serine, 23
heat shock 70kDa protein 4
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Extracellular Vesicular Exosome
Mitochondrion
Cytosol
Extracellular Vesicular Exosome
Molecular Function
Serine-type Endopeptidase Activity
ATP Binding
Biological Process
Proteolysis
Response To Unfolded Protein
Protein Import Into Mitochondrial Outer Membrane
Chaperone-mediated Protein Complex Assembly
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
25 interactors:
ACTG1
APP
B2M
CHP1
EFNA3
FXR1
GRK6
HSPA4
MAPK8IP2
NCAPD3
NIPBL
NOC4L
ODF2L
PDDC1
PDPK1
PHF23
PPIA
RACGAP1
RECQL4
RPL4P5
SHMT1
SLC25A6
TCF12
TMEM222
TRAPPC4
58 interactors:
AGTRAP
APPBP2
BAG1
BAG2
BAG5
BRMS1
CALM1
CD40
CDC73
CDKN2A
CSNK1A1
CSNK2A1
DDIT4
DNAJB1
DUSP1
EGFR
ESR1
FANCC
FES
FKBP4
GATA1
GRPEL2
GSK3B
GZMA
HAP1
HDAC3
HNRNPD
HSPBP1
IKBKG
KPNA2
KRT18
MAPT
NFKB1
NR3C2
OLR1
PHLDA1
PPP1CA
PRKCB
PRKCD
PRKCG
PRSS23
PSMD10
RAF1
REL
RELA
SMAD3
SOD1
ST13
STIP1
STUB1
SUGT1
TERT
TIMM44
TOMM40
TRAF6
TTC1
UBE2L3
UBE3A
Entrez ID
11098
3308
HPRD ID
07149
09025
Ensembl ID
ENSG00000150687
Uniprot IDs
B4E2J3
O95084
P34932
PDB IDs
Enriched GO Terms of Interacting Partners
?
Platelet Activation
Blood Coagulation
Hemostasis
Cell Differentiation
Cellular Component Assembly
Regulation Of Body Fluid Levels
Organelle Organization
Wound Healing
Multicellular Organismal Development
Generation Of Neurons
Cell Activation
Dendrite Development
System Development
Response To Stress
Response To Wounding
Neurogenesis
Mating Behavior
Nervous System Development
Regulation Of Protein Localization
Response To Stimulus
Neuron Projection Development
Cell Development
Developmental Process
Cytokinesis, Initiation Of Separation
Actomyosin Contractile Ring Assembly
Uncoating Of Virus
Mating
Anatomical Structure Development
Neuron Development
Retina Homeostasis
Movement Of Cell Or Subcellular Component
Cell Morphogenesis Involved In Neuron Differentiation
Protein Targeting To Mitochondrion
Protein Complex Assembly
Regulation Of Cellular Localization
Immune System Process
Platelet Degranulation
Negative Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity
Synaptic Growth At Neuromuscular Junction
Active Induction Of Host Immune Response By Virus
Mitotic Sister Chromatid Segregation
Protein Localization To Mitochondrion
Protein Folding
Cognition
Neuron Projection Morphogenesis
Positive Regulation Of Cellular Protein Metabolic Process
Neuron Differentiation
Mitotic Nuclear Division
Sister Chromatid Segregation
Regulation Of Establishment Of Protein Localization
Regulation Of Cell Death
Regulation Of Apoptotic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cell Death
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Protein Metabolic Process
Response To Organic Substance
Regulation Of Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Cell Death
Death
Neurotrophin Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Regulation Of Signaling
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Response To Stress
Cellular Response To Growth Factor Stimulus
Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Response To Growth Factor
Cellular Response To Stimulus
Programmed Cell Death
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Modification Process
Negative Regulation Of Signal Transduction
Cellular Metabolic Process
Signaling
Response To Stimulus
Cell Communication
Regulation Of Metabolic Process
Negative Regulation Of Signaling
Positive Regulation Of Cell Death
Cellular Protein Metabolic Process
Signal Transduction
Regulation Of Protein Phosphorylation
Immune System Process
Regulation Of Catalytic Activity
Positive Regulation Of Cellular Biosynthetic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Tagcloud
?
competence
cumulus
damaged
domestic
fertility
hfs2
hsf
hsf1
hsp110
hsp40
hsp90a
hsp90b
hsph1
hsps
machinery
oocyte
oocytes
operational
ovaries
ovary
pig
preserve
sows
summer
unexpectedly
warm
winter
Tagcloud (Difference)
?
competence
cumulus
damaged
domestic
fertility
hfs2
hsf
hsf1
hsp110
hsp40
hsp90a
hsp90b
hsph1
hsps
machinery
oocyte
oocytes
operational
ovaries
ovary
pig
preserve
sows
summer
unexpectedly
warm
winter
Tagcloud (Intersection)
?