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HSPA4 and TIMM44
Number of citations of the paper that reports this interaction (PMID
12677068
)
32
Data Source:
BioGRID
(pull down)
HSPA4
TIMM44
Gene Name
heat shock 70kDa protein 4
translocase of inner mitochondrial membrane 44 homolog (yeast)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Cytosol
Extracellular Vesicular Exosome
Mitochondrion
Mitochondrial Inner Membrane
Mitochondrial Matrix
Molecular Function
ATP Binding
Protein Binding
ATP Binding
P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity
Chaperone Binding
Biological Process
Response To Unfolded Protein
Protein Import Into Mitochondrial Outer Membrane
Chaperone-mediated Protein Complex Assembly
Protein Targeting To Mitochondrion
Protein Import Into Mitochondrial Matrix
Cellular Protein Metabolic Process
Pathways
Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions
58 interactors:
AGTRAP
APPBP2
BAG1
BAG2
BAG5
BRMS1
CALM1
CD40
CDC73
CDKN2A
CSNK1A1
CSNK2A1
DDIT4
DNAJB1
DUSP1
EGFR
ESR1
FANCC
FES
FKBP4
GATA1
GRPEL2
GSK3B
GZMA
HAP1
HDAC3
HNRNPD
HSPBP1
IKBKG
KPNA2
KRT18
MAPT
NFKB1
NR3C2
OLR1
PHLDA1
PPP1CA
PRKCB
PRKCD
PRKCG
PRSS23
PSMD10
RAF1
REL
RELA
SMAD3
SOD1
ST13
STIP1
STUB1
SUGT1
TERT
TIMM44
TOMM40
TRAF6
TTC1
UBE2L3
UBE3A
5 interactors:
ARAF
CMTM5
HSPA4
PRPF6
TIMM17A
Entrez ID
3308
10469
HPRD ID
09025
05450
Ensembl ID
ENSG00000104980
Uniprot IDs
P34932
O43615
PDB IDs
2CW9
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Death
Regulation Of Apoptotic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Cellular Response To Organic Substance
Negative Regulation Of Cell Death
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Positive Regulation Of Protein Metabolic Process
Response To Organic Substance
Regulation Of Signal Transduction
Neurotrophin TRK Receptor Signaling Pathway
Cell Death
Death
Neurotrophin Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Regulation Of Signaling
Negative Regulation Of Protein Metabolic Process
Positive Regulation Of Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Response To Stress
Cellular Response To Growth Factor Stimulus
Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Apoptotic Process
Response To Growth Factor
Cellular Response To Stimulus
Programmed Cell Death
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Modification Process
Negative Regulation Of Signal Transduction
Cellular Metabolic Process
Signaling
Response To Stimulus
Cell Communication
Regulation Of Metabolic Process
Negative Regulation Of Signaling
Positive Regulation Of Cell Death
Cellular Protein Metabolic Process
Signal Transduction
Regulation Of Protein Phosphorylation
Immune System Process
Regulation Of Catalytic Activity
Positive Regulation Of Cellular Biosynthetic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Surface Receptor Signaling Pathway
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Protein Transmembrane Transport
Protein Targeting To Mitochondrion
Protein Localization To Mitochondrion
Mitochondrial Transport
Protein Import Into Mitochondrial Outer Membrane
Establishment Of Protein Localization To Organelle
Mitochondrion Organization
Chaperone-mediated Protein Complex Assembly
Spliceosomal Tri-snRNP Complex Assembly
Protein Targeting
Protein Localization To Organelle
Negative Regulation Of Myoblast Differentiation
Tagcloud
?
competence
cumulus
damaged
domestic
fertility
hfs2
hsf
hsf1
hsp110
hsp40
hsp90a
hsp90b
hsph1
hsps
machinery
oocyte
oocytes
operational
ovaries
ovary
pig
preserve
sows
summer
unexpectedly
warm
winter
Tagcloud (Difference)
?
competence
cumulus
damaged
domestic
fertility
hfs2
hsf
hsf1
hsp110
hsp40
hsp90a
hsp90b
hsph1
hsps
machinery
oocyte
oocytes
operational
ovaries
ovary
pig
preserve
sows
summer
unexpectedly
warm
winter
Tagcloud (Intersection)
?