TIMM44 and PRPF6

Number of citations of the paper that reports this interaction (PMID 10848612)
10

Data Source:
BioGRID (two hybrid)

		TIMM44	PRPF6
Gene Name		translocase of inner mitochondrial membrane 44 homolog (yeast)	pre-mRNA processing factor 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Membrane Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding ATP Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Chaperone Binding	Transcription Coactivator Activity RNA Binding Protein Binding Ribonucleoprotein Complex Binding Poly(A) RNA Binding Androgen Receptor Binding
	Biological Process	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Cellular Protein Metabolic Process	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Localization RNA Splicing Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Mitochondrial protein import	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Minor Pathway mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		5 interactors: ARAF CMTM5 HSPA4 PRPF6 TIMM17A	13 interactors: AR ARAF CD2BP2 EFTUD2 ESR1 NR3C1 RAF1 SMARCA2 SRRM2 TIMM44 TXNL4A TXNL4B YWHAB
Entrez ID		10469	24148
HPRD ID		05450	10729
Ensembl ID		ENSG00000104980	ENSG00000101161
Uniprot IDs		O43615	O94906
PDB IDs		2CW9
Enriched GO Terms of Interacting Partners?		Protein Transmembrane Transport Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport Protein Import Into Mitochondrial Outer Membrane Establishment Of Protein Localization To Organelle Mitochondrion Organization Chaperone-mediated Protein Complex Assembly Spliceosomal Tri-snRNP Complex Assembly Protein Targeting Protein Localization To Organelle Negative Regulation Of Myoblast Differentiation	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Gene Expression MRNA Processing Intracellular Steroid Hormone Receptor Signaling Pathway RNA Metabolic Process MRNA Metabolic Process Cellular Response To Hormone Stimulus RNA Processing Cellular Metabolic Process Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Regulation Of Apoptotic Process Regulation Of Cell Death Response To Hormone Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Ribonucleoprotein Complex Assembly Nucleobase-containing Compound Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process DNA-templated Transcription, Initiation Cellular Nitrogen Compound Metabolic Process Cellular Component Assembly Mammary Gland Duct Morphogenesis Spliceosomal Complex Assembly Nitrogen Compound Metabolic Process Organelle Organization Death-inducing Signaling Complex Assembly Negative Regulation Of Integrin Biosynthetic Process Glucocorticoid Mediated Signaling Pathway Activation Of MAPKK Activity Negative Regulation Of Dephosphorylation Prostate Gland Development Ribonucleoprotein Complex Biogenesis Regulation Of Phosphorus Metabolic Process Positive Regulation Of Peptidyl-serine Phosphorylation Metabolic Process Mammary Gland Morphogenesis Positive Regulation Of Phosphorylation Positive Regulation Of Metabolic Process Transcription From RNA Polymerase II Promoter Cellular Response To Organic Cyclic Compound Positive Regulation Of Cellular Biosynthetic Process Aortic Smooth Muscle Cell Differentiation Mammary Gland Epithelium Development Cellular Response To Lipid
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