TIMM44 and HSPA4

Number of citations of the paper that reports this interaction (PMID 12677068)
32

Data Source:
BioGRID (pull down)

		TIMM44	HSPA4
Gene Name		translocase of inner mitochondrial membrane 44 homolog (yeast)	heat shock 70kDa protein 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix	Mitochondrion Cytosol Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding P-P-bond-hydrolysis-driven Protein Transmembrane Transporter Activity Chaperone Binding	ATP Binding
	Biological Process	Protein Targeting To Mitochondrion Protein Import Into Mitochondrial Matrix Cellular Protein Metabolic Process	Response To Unfolded Protein Protein Import Into Mitochondrial Outer Membrane Chaperone-mediated Protein Complex Assembly
Pathways		Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ARAF CMTM5 HSPA4 PRPF6 TIMM17A	58 interactors: AGTRAP APPBP2 BAG1 BAG2 BAG5 BRMS1 CALM1 CD40 CDC73 CDKN2A CSNK1A1 CSNK2A1 DDIT4 DNAJB1 DUSP1 EGFR ESR1 FANCC FES FKBP4 GATA1 GRPEL2 GSK3B GZMA HAP1 HDAC3 HNRNPD HSPBP1 IKBKG KPNA2 KRT18 MAPT NFKB1 NR3C2 OLR1 PHLDA1 PPP1CA PRKCB PRKCD PRKCG PRSS23 PSMD10 RAF1 REL RELA SMAD3 SOD1 ST13 STIP1 STUB1 SUGT1 TERT TIMM44 TOMM40 TRAF6 TTC1 UBE2L3 UBE3A
Entrez ID		10469	3308
HPRD ID		05450	09025
Ensembl ID		ENSG00000104980
Uniprot IDs		O43615	P34932
PDB IDs		2CW9
Enriched GO Terms of Interacting Partners?		Protein Transmembrane Transport Protein Targeting To Mitochondrion Protein Localization To Mitochondrion Mitochondrial Transport Protein Import Into Mitochondrial Outer Membrane Establishment Of Protein Localization To Organelle Mitochondrion Organization Chaperone-mediated Protein Complex Assembly Spliceosomal Tri-snRNP Complex Assembly Protein Targeting Protein Localization To Organelle Negative Regulation Of Myoblast Differentiation	Regulation Of Cell Death Regulation Of Apoptotic Process Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Regulation Of Cellular Protein Metabolic Process Cellular Response To Organic Substance Negative Regulation Of Cell Death Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Protein Metabolic Process Response To Organic Substance Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Cell Death Death Neurotrophin Signaling Pathway Positive Regulation Of Cellular Metabolic Process Regulation Of Signaling Negative Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Cellular Metabolic Process Response To Stress Cellular Response To Growth Factor Stimulus Protein Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process Apoptotic Process Response To Growth Factor Cellular Response To Stimulus Programmed Cell Death Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Negative Regulation Of Signal Transduction Cellular Metabolic Process Signaling Response To Stimulus Cell Communication Regulation Of Metabolic Process Negative Regulation Of Signaling Positive Regulation Of Cell Death Cellular Protein Metabolic Process Signal Transduction Regulation Of Protein Phosphorylation Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death
Tagcloud ?			competence cumulus damaged domestic fertility hfs2 hsf hsf1 hsp110 hsp40 hsp90a hsp90b hsph1 hsps machinery oocyte oocytes operational ovaries ovary pig preserve sows summer unexpectedly warm winter
Tagcloud (Difference) ?			competence cumulus damaged domestic fertility hfs2 hsf hsf1 hsp110 hsp40 hsp90a hsp90b hsph1 hsps machinery oocyte oocytes operational ovaries ovary pig preserve sows summer unexpectedly warm winter
Tagcloud (Intersection) ?