HSF4 and CDK2AP2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		HSF4	CDK2AP2
Gene Name		heat shock transcription factor 4	cyclin-dependent kinase 2 associated protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Phosphatase Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation Histone H3-K9 Demethylation Camera-type Eye Development Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Development Protein Homotrimerization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CDK2AP2 DUSP26 MAPK1 MAPK14 MAPK3 MAPK8 NUDT21 SLC27A5 SMARCA4 ZBED8	17 interactors: A2M APP CDK2AP1 DBN1 EED EEF1G HSF4 IKZF1 MBTPS1 MRFAP1L1 PYCR1 RCC1 RPLP1 TRA2A WARS YIF1A ZBTB48
Entrez ID		3299	10263
HPRD ID		03896	13242
Ensembl ID		ENSG00000102878	ENSG00000167797
Uniprot IDs		Q9ULV5	O75956 Q6IAV4
PDB IDs			2M1L
Enriched GO Terms of Interacting Partners?		Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Cellular Response To Lipopolysaccharide Cellular Response To Molecule Of Bacterial Origin Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Innate Immune Response Neurotrophin TRK Receptor Signaling Pathway MAPK Cascade Regulation Of Golgi Inheritance Neurotrophin Signaling Pathway Regulation Of Innate Immune Response Caveolin-mediated Endocytosis Signal Transduction By Phosphorylation Response To Lipopolysaccharide Regulation Of Golgi Organization Response To Molecule Of Bacterial Origin Vascular Endothelial Growth Factor Receptor Signaling Pathway Peptidyl-amino Acid Modification Regulation Of Early Endosome To Late Endosome Transport Cellular Response To Lipid Peptidyl-serine Phosphorylation Regulation Of Intracellular Transport Immune Response-regulating Signaling Pathway Response To Bacterium Activation Of MAPK Activity Positive Regulation Of Signal Transduction Cellular Response To Growth Factor Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Growth Factor Platelet Activation Growth Hormone Receptor Signaling Pathway Regulation Of MAPK Cascade Cellular Response To Growth Hormone Stimulus Positive Regulation Of Immune Response	Gene Expression Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclease Activity Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Platelet Degranulation Cellular Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Macromolecule Biosynthetic Process Tryptophanyl-tRNA Aminoacylation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Complement Activation, Lectin Pathway Cellular Aromatic Compound Metabolic Process Biosynthetic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Metabolic Process Regulation Of Protein Metabolic Process Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Multicellular Organism Growth Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Positive Regulation Of Protein Modification Process Cholesterol Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition L-proline Biosynthetic Process Sterol Metabolic Process Response To Unfolded Protein Cellular Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Hydrolase Activity Protein Metabolic Process Axon Choice Point Recognition Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Phosphorylation MRNA Metabolic Process Histone H3-K9 Demethylation Response To Endoplasmic Reticulum Stress Positive Regulation Of Ran GTPase Activity Positive Regulation Of Granulocyte Differentiation
Tagcloud ?		a3 bf blinding cataract cataracts congenital constantly cryaa cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygc crygd crygs crystallin ftl gja1 gja3 gja8 lim2 maf mip pax6 pitx3 sp2 summarized
Tagcloud (Difference) ?		a3 bf blinding cataract cataracts congenital constantly cryaa cryab cryba1 cryba4 crybb1 crybb2 crybb3 crygc crygd crygs crystallin ftl gja1 gja3 gja8 lim2 maf mip pax6 pitx3 sp2 summarized
Tagcloud (Intersection) ?