CDK2AP2 and DBN1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		CDK2AP2	DBN1
Gene Name		cyclin-dependent kinase 2 associated protein 2	drebrin 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Cytoplasm Plasma Membrane Gap Junction Cell Cortex Actin Cytoskeleton Dendrite Actomyosin
	Molecular Function		Actin Binding Protein Binding Profilin Binding
	Biological Process		Actin Filament Organization Cell Communication By Chemical Coupling Cell Communication By Electrical Coupling Maintenance Of Protein Location In Cell Regulation Of Neuronal Synaptic Plasticity Regulation Of Dendrite Development Neural Precursor Cell Proliferation
Pathways
Drugs
Diseases
GWAS			Activated partial thromboplastin time ( 22703881)
Protein-Protein Interactions		17 interactors: A2M APP CDK2AP1 DBN1 EED EEF1G HSF4 IKZF1 MBTPS1 MRFAP1L1 PYCR1 RCC1 RPLP1 TRA2A WARS YIF1A ZBTB48	24 interactors: ACD BAK1 BTRC CDK2AP2 DNMBP DUSP23 FHL1 HOMER2 MAP1LC3B MAPK6 MEST NIPBL NUDT21 NUDT3 PFN1 POT1 SNUPN SUPT5H TAB1 TERF1 TINF2 TPT1 UBE2D3 ZNF598
Entrez ID		10263	1627
HPRD ID		13242	00545
Ensembl ID		ENSG00000167797	ENSG00000113758
Uniprot IDs		O75956 Q6IAV4	F8W9Z3 Q16643
PDB IDs		2M1L
Enriched GO Terms of Interacting Partners?		Gene Expression Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclease Activity Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Platelet Degranulation Cellular Macromolecule Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Macromolecule Biosynthetic Process Tryptophanyl-tRNA Aminoacylation Synaptic Growth At Neuromuscular Junction Negative Regulation Of Complement Activation, Lectin Pathway Cellular Aromatic Compound Metabolic Process Biosynthetic Process Endoplasmic Reticulum Unfolded Protein Response Cellular Metabolic Process Regulation Of Protein Metabolic Process Collateral Sprouting In Absence Of Injury Cell Communication By Chemical Coupling Regulation Of Multicellular Organism Growth Cellular Response To Unfolded Protein ER-nucleus Signaling Pathway Cellular Response To Topologically Incorrect Protein Positive Regulation Of Protein Modification Process Cholesterol Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition L-proline Biosynthetic Process Sterol Metabolic Process Response To Unfolded Protein Cellular Protein Metabolic Process Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Hydrolase Activity Protein Metabolic Process Axon Choice Point Recognition Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Phosphorylation MRNA Metabolic Process Histone H3-K9 Demethylation Response To Endoplasmic Reticulum Stress Positive Regulation Of Ran GTPase Activity Positive Regulation Of Granulocyte Differentiation	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Telomere Assembly Negative Regulation Of DNA Replication Regulation Of Telomerase Activity Telomere Maintenance Regulation Of Chromosome Organization Negative Regulation Of Chromosome Organization Positive Regulation Of Organelle Organization Negative Regulation Of DNA Metabolic Process Telomere Maintenance Via Telomere Lengthening Regulation Of DNA Replication Positive Regulation Of DNA Metabolic Process Regulation Of DNA Biosynthetic Process Protein Localization To Chromosome, Telomeric Region Telomere Capping Regulation Of Organelle Organization Negative Regulation Of Biosynthetic Process Positive Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomerase Activity Positive Regulation Of Telomere Maintenance Negative Regulation Of Cellular Metabolic Process Homeostatic Process Positive Regulation Of DNA Biosynthetic Process RNA-dependent DNA Replication Regulation Of Cellular Component Organization Negative Regulation Of DNA Biosynthetic Process Chromosome Organization Positive Regulation Of Cellular Metabolic Process DNA Metabolic Process Positive Regulation Of Catalytic Activity Protein Localization To Chromosome Tube Development Positive Regulation Of Metabolic Process Tube Morphogenesis Limb Morphogenesis Regulation Of Catalytic Activity Limb Development Positive Regulation Of Viral Transcription Negative Regulation Of Protein ADP-ribosylation SnRNA Import Into Nucleus Diphosphoinositol Polyphosphate Catabolic Process Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Diadenosine Polyphosphate Catabolic Process Organelle Organization Cellular Component Assembly
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