HSF4 and SLC27A5

Number of citations of the paper that reports this interaction (PubMedID 16552721)
0

Data Source:
HPRD (in vitro, in vivo)

		HSF4	SLC27A5
Description		heat shock transcription factor 4	solute carrier family 27 member 5
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nuclear Speck	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Basal Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Phosphatase Binding Identical Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Long-chain Fatty Acid Transmembrane Transporter Activity Protein Binding ATP Binding Fatty Acid Transmembrane Transporter Activity Oxidoreductase Activity Ligase Activity Very Long-chain Fatty Acid-CoA Ligase Activity Protein-containing Complex Binding Cholate-CoA Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Lens Fiber Cell Differentiation	Very Long-chain Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Triglyceride Mobilization Bile Acid Biosynthetic Process Lipid Transport Bile Acid Metabolic Process Bile Acid And Bile Salt Transport Fatty Acid Transport Long-chain Fatty Acid Transport Long-chain Fatty Acid Import Across Plasma Membrane Long-chain Fatty Acid Import Into Cell Ketone Body Biosynthetic Process Establishment Of Localization In Cell
Pathways			Recycling of bile acids and salts Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Synthesis of bile acids and bile salts via 24-hydroxycholesterol
Drugs
Diseases
GWAS			Heel bone mineral density ( 30598549) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Mean reticulocyte volume ( 32888494)
Interacting Genes		43 interacting genes: ACTMAP AKAP8L ALKBH4 C10orf55 CDK2AP2 DAXX DUSP26 FAM168B FAM200C FOXH1 FOXI1 GFOD1 HGS INTS11 KRT31 KRT37 KRT38 KRT40 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP6-2 MAPK1 MAPK14 MAPK3 MAPK8 MKRN3 NHLRC4 NUDT21 NUP62 OIP5 PIH1D2 PITX1 PLA2G10 PPFIBP2 SESTD1 SLC27A5 SMARCA4 SOX10 TPM3 UFSP1 YTHDF1 ZMYND12	3 interacting genes: HNRNPD HSF4 MEOX2
Entrez ID		3299	10998
HPRD ID		03896	04499
Ensembl ID		ENSG00000102878	ENSG00000083807
Uniprot IDs		Q9ULV5	Q9Y2P5
PDB IDs		6J6V 6J6W
Enriched GO Terms of Interacting Partners?		Intermediate Filament MAP Kinase Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Keratin Filament Protein Binding Structural Constituent Of Skin Epidermis Interleukin-34-mediated Signaling Pathway Positive Regulation Of Cyclase Activity Nuclear Androgen Receptor Binding Intermediate Filament Organization Regulation Of Golgi Inheritance Caveolin-mediated Endocytosis Positive Regulation Of Macrophage Proliferation Anatomical Structure Morphogenesis Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Lipopolysaccharide-mediated Signaling Pathway Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Morphogenesis Of An Epithelium Outer Ear Morphogenesis ERBB3 Signaling Pathway ERBB2-ERBB3 Signaling Pathway Bergmann Glial Cell Differentiation MAPK Cascade Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of RNA Metabolic Process Cellular Senescence Tissue Morphogenesis Cellular Response To Amino Acid Starvation Response To Amino Acid Starvation Glial Cell Development Negative Regulation Of Cholesterol Efflux Regulation Of Gene Expression P53 Binding Regulation Of Golgi Organization Pseudopodium Negative Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Regulation Of Early Endosome To Late Endosome Transport Schwann Cell Development Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Macrophage Chemotaxis Animal Organ Formation Negative Regulation Of Cholesterol Transport	Hepatocyte Dedifferentiation Cellular Response To Putrescine Chromatin Circadian Regulation Of Translation Response To Rapamycin Positive Regulation Of Telomere Capping Cell Dedifferentiation MCRD-mediated MRNA Stability Complex Somite Specification Cellular Response To Nitric Oxide Positive Regulation Of Cytoplasmic Translation 3'-UTR-mediated MRNA Destabilization CRD-mediated MRNA Stabilization DNA Binding Response To Sodium Phosphate Minor Groove Of Adenine-thymine-rich DNA Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Telomere Capping Cellular Response To Reactive Nitrogen Species Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear Speck Lens Fiber Cell Differentiation Sequence-specific DNA Binding Segment Specification Somite Development Sequence-specific Double-stranded DNA Binding Response To Nitric Oxide Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Response To Ether Positive Regulation Of Telomere Maintenance Via Telomerase Response To Salt Telomeric DNA Binding MRNA 3'-UTR AU-rich Region Binding Positive Regulation Of Telomere Maintenance Via Telomere Lengthening DNA-binding Transcription Factor Activity Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of DNA-templated Transcription Cellular Response To Estradiol Stimulus Regulation Of Cytoplasmic Translation Regulation Of RNA Biosynthetic Process Response To Electrical Stimulus Regulation Of Telomere Maintenance Via Telomerase Regulation Of RNA Metabolic Process Positive Regulation Of DNA Biosynthetic Process Cerebellum Development Regulation Of Telomere Maintenance Via Telomere Lengthening RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Cell Migration Involved In Sprouting Angiogenesis Limb Development Negative Regulation Of Blood Vessel Endothelial Cell Migration
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