HSBP1 and CCHCR1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HSBP1	CCHCR1
Gene Name		heat shock factor binding protein 1	coiled-coil alpha-helical rod protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoskeleton	Nucleus Cytoplasm Centriole
	Molecular Function	Transcription Corepressor Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Muscle Contraction Cellular Response To Heat Endodermal Cell Differentiation Regulation Of Cellular Response To Heat	Protein Export From Nucleus Multicellular Organismal Development Cell Differentiation
Pathways		HSF1 activation HSF1-dependent transactivation Attenuation phase Cellular response to heat stress
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Hematology traits ( 23263863) Nevirapine-induced rash ( 21810746) Prostate cancer ( 21743467) Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS-TEN) ( 21912425) White blood cell count ( 21738480)
Protein-Protein Interactions		11 interactors: CCDC53 CCHCR1 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP10-3 KRTAP10-7 LNX1 NOTCH2NL SDCBP	57 interactors: ABI2 ALAS1 AMOTL2 ATG5 BLOC1S6 C1orf94 CARD9 CCDC102B CCDC136 CCDC53 CDR2 CEP55 CTAGE5 DTNBP1 EFHC2 FSD2 GOLGA2 HAUS1 HSBP1 IKBKG KRT13 KRT15 KRT31 KRT40 MAD1L1 MED4 MID2 MTUS2 NAB2 NDC80 NDEL1 NINL NME7 NUP62 NUTM1 PIAS2 POLD2 POLR2C PRKCG RBM17 SAT1 SPAG5 SSX2IP STAR TADA2A TEKT1 TFIP11 TPM3 TRAF1 TRAF2 TRAF4 TRIM27 TSGA10 TXLNA TXLNB USHBP1 ZFYVE19
Entrez ID		3281	54535
HPRD ID		05185	05607
Ensembl ID		ENSG00000230989	ENSG00000204536
Uniprot IDs		O75506	B0S7V6 D2IYK9 M1T2K8 M1TIV4 Q2TB68 Q769H0 Q8TD31
PDB IDs		3CI9
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Response To Heat Cellular Response To Heat Response To Heat Cellular Heat Acclimation Zonula Adherens Maintenance	Mitotic Cell Cycle Mitotic Cell Cycle Process Microtubule-based Transport Activation Of NF-kappaB-inducing Kinase Activity Cytoskeleton-dependent Intracellular Transport Organelle Organization Positive Regulation Of NIK/NF-kappaB Signaling Cell Cycle Process NIK/NF-kappaB Signaling Mitotic Nuclear Division Cell Cycle Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Microtubule-based Process Positive Regulation Of NF-kappaB Transcription Factor Activity Axon Cargo Transport Innate Immune Response Cell Division Positive Regulation Of Protein Homodimerization Activity Cytoskeleton Organization Microtubule-based Movement Establishment Of Organelle Localization Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Viral Release From Host Cell Establishment Of Vesicle Localization Intracellular Receptor Signaling Pathway Anterograde Synaptic Vesicle Transport Negative Regulation Of Neuron Death Vesicle Localization Regulation Of Protein Homodimerization Activity Centrosome Organization Negative Regulation Of Viral Transcription Melanosome Organization Establishment Of Localization In Cell Pigment Granule Organization Regulation Of Viral Release From Host Cell Regulation Of I-kappaB Kinase/NF-kappaB Signaling Developmental Process Organelle Localization Microtubule Organizing Center Organization Cellular Localization Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Anterograde Axon Cargo Transport Regulation Of Apoptotic Process Microtubule Cytoskeleton Organization Positive Regulation Of JNK Cascade Spindle Organization Regulation Of Cell Death
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