HSBP1 and CCDC53

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)
HPRD (two hybrid)

		HSBP1	CCDC53
Gene Name		heat shock factor binding protein 1	coiled-coil domain containing 53
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoskeleton	Actin Cytoskeleton Intracellular Membrane-bounded Organelle WASH Complex
	Molecular Function	Transcription Corepressor Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Muscle Contraction Cellular Response To Heat Endodermal Cell Differentiation Regulation Of Cellular Response To Heat	Biological_process
Pathways		HSF1 activation HSF1-dependent transactivation Attenuation phase Cellular response to heat stress
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: CCDC53 CCHCR1 HSF1 HSPA1A KIAA1217 KIFC3 KRTAP10-3 KRTAP10-7 LNX1 NOTCH2NL SDCBP	28 interactors: ABI2 BLOC1S6 CCHCR1 CEP55 CKAP4 DTNBP1 GDF9 GOLGA2 HAUS1 HSBP1 IFT20 KDM1A KRT6A LAMC1 LUC7L2 MCRS1 MOB1B NDC80 NUP62 OPTN PBXIP1 PCM1 PTN SDCBP SNAP25 SYCE1 TXLNA TXLNB
Entrez ID		3281	51019
HPRD ID		05185	13031
Ensembl ID		ENSG00000230989	ENSG00000120860
Uniprot IDs		O75506	F5GZ97 Q9Y3C0
PDB IDs		3CI9
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Response To Heat Cellular Response To Heat Response To Heat Cellular Heat Acclimation Zonula Adherens Maintenance	Organelle Organization Cell Differentiation Establishment Of Localization In Cell Organelle Localization Mitotic Cell Cycle Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Localization Developmental Process Synaptic Vesicle Docking Cell Cycle Mitotic Cell Cycle Process Cell Development Nervous System Development Cell Cycle Process Protein Localization Post-Golgi Vesicle-mediated Transport Microtubule-based Process Intracellular Transport Generation Of Neurons Cell Projection Organization Anterograde Synaptic Vesicle Transport Synaptic Vesicle Transport Membrane Organization Neurogenesis Melanosome Organization Pigment Granule Organization Microtubule-based Movement Anterograde Axon Cargo Transport Establishment Of Organelle Localization Neuron Development Cellular Process Multicellular Organismal Development Cellular Component Assembly Intraciliary Transport Establishment Of Protein Localization Anatomical Structure Development Movement Of Cell Or Subcellular Component Protein Localization To Golgi Apparatus Cytoskeleton Organization Neuron Differentiation Cell Division Regulation Of Primitive Erythrocyte Differentiation Opsin Transport Establishment Of Vesicle Localization Axon Cargo Transport Vesicle Organization Vesicle Localization Neuron Projection Development Positive Regulation Of Cell Proliferation
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