PRMT1 and TAF15

Number of citations of the paper that reports this interaction (PMID 12183049)
12

Data Source:
BioGRID (enzymatic study)

		PRMT1	TAF15
Gene Name		protein arginine methyltransferase 1	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Protein Binding Methyltransferase Activity N-methyltransferase Activity Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Identical Protein Binding Histone Methyltransferase Activity (H4-R3 Specific) Poly(A) RNA Binding	Nucleotide Binding DNA Binding Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Protein Methylation Cell Surface Receptor Signaling Pathway Histone Methylation Peptidyl-arginine Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Neuron Projection Development Histone H4-R3 Methylation Negative Regulation Of Megakaryocyte Differentiation	Positive Regulation Of Transcription, DNA-templated
Pathways		Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS
Protein-Protein Interactions		93 interactors: AR ARPC3 ASH2L AXIN1 BRCA1 BTG1 BTG2 C17orf53 C20orf196 C4orf17 CAPRIN1 CDC37 CEP162 CIRBP CNOT8 COIL DAXX DCAF16 DCAF8 DHX9 EIF4A1 ESR1 EWSR1 FAM83D FAM9A FBL FGF2 FLII FUS GPATCH2L GRHL3 GRIP1 HABP4 HIST1H3A HIST1H4A HIST2H4A HIST4H4 HNF4A HNRNPA1 HNRNPK HNRNPR HNRNPU HNRNPUL1 IDH3B IFNAR1 IGSF21 ILF3 KHDRBS1 KHDRBS2 KHDRBS3 LRIF1 MBP MECOM MED31 MLST8 NCOA1 NCOA2 NCOA3 NOL4 NRIP1 OFCC1 PIAS1 PPARA PRMT8 QKI RELA RNF187 RUNX1 S100A8 SAMD3 SPAG8 SPEG SPSB1 SPSB2 STAT1 STAT5A SUPT5H SYNCRIP TAF15 TBX6 TERF2 THRB TP53 VHL VPS72 WDFY3 WDR33 WDYHV1 YLPM1 YWHAG ZBTB14 ZMYM5 ZNF451	21 interactors: CACNA1A FUS HIST1H3A HIST2H2AC HIST2H4A HIST3H3 POLR2C POLR2E POLR2G PRMT1 PRMT8 SAFB SF1 TAF1 TAF12 TAF13 TAF5 TAF7 TBP YWHAG ZNF384
Entrez ID		3276	8148
HPRD ID		04257	09031
Ensembl ID		ENSG00000126457	ENSG00000172660
Uniprot IDs		B4DJ87 H7C2I1 Q99873	Q86X94 Q92804
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Gene Expression Gene Expression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Metabolic Process Intracellular Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Androgen Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Negative Regulation Of Cellular Metabolic Process Biosynthetic Process Transcription From RNA Polymerase II Promoter Regulation Of Cellular Process MRNA Processing Chromatin Organization Cellular Process Chromatin Modification Response To Hormone MRNA Metabolic Process RNA Processing Chromosome Organization Cellular Response To Hormone Stimulus Metabolic Process Response To Organic Substance	Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation DNA-templated Transcription, Elongation Transcription From RNA Polymerase II Promoter Gene Expression Viral Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Chromosome Organization Chromatin Organization Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process RNA Metabolic Process Chromatin Silencing At RDNA Regulation Of Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Histone Modification MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression 7-methylguanosine MRNA Capping PiRNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Chromatin Silencing 7-methylguanosine RNA Capping Transcription-coupled Nucleotide-excision Repair Negative Regulation Of Megakaryocyte Differentiation Cellular Metabolic Process Positive Regulation Of Viral Transcription Regulation Of Transcription, DNA-templated Chromatin Modification Cellular Macromolecule Biosynthetic Process RNA Splicing Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine MRNA Processing Negative Regulation Of Hematopoietic Progenitor Cell Differentiation DNA Replication-dependent Nucleosome Assembly Somatic Stem Cell Maintenance Regulation Of Gene Expression, Epigenetic
Tagcloud ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping hnrnpa1 hnrnpa2b1 lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution tardbp tdp43 tremor
Tagcloud (Difference) ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt2 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping hnrnpa1 hnrnpa2b1 lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution tardbp tdp43 tremor
Tagcloud (Intersection) ?