PRMT2 and SPAG8

Number of citations of the paper that reports this interaction (PMID 23455924)
3

Data Source:
BioGRID (two hybrid)

		PRMT2	SPAG8
Gene Name		protein arginine methyltransferase 2	sperm associated antigen 8
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Rb-E2F Complex	Acrosomal Vesicle Nucleus Membrane
	Molecular Function	Transcription Coactivator Activity Signal Transducer Activity Protein Binding Histone-arginine N-methyltransferase Activity Protein-arginine N-methyltransferase Activity Estrogen Receptor Binding Progesterone Receptor Binding Protein-arginine Omega-N Asymmetric Methyltransferase Activity Histone Methyltransferase Activity Protein Homodimerization Activity Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Thyroid Hormone Receptor Binding Androgen Receptor Binding	Molecular_function Microtubule Binding
	Biological Process	Protein Methylation Signal Transduction Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of NF-kappaB Transcription Factor Activity Histone Arginine Methylation Positive Regulation Of Apoptotic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Developmental Cell Growth Regulation Of Androgen Receptor Signaling Pathway Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Biological_process Positive Regulation Of Protein Binding Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: BAG6 CPSF7 DMRTB1 ESR1 ESR2 FIP1L1 HNRNPA1 HNRNPUL1 NCOA1 NCOA6 PGR PRRC2A PSMB3 RB1 RIPK2 RXRA SPAG8 THRB	15 interactors: CARM1 CSTF2 DTX2 JMJD4 KDM3B KLHL32 NEDD4L PITX1 PRMT1 PRMT2 PRMT5 RAN SNRPC UBQLN4 WHSC1L1
Entrez ID		3275	26206
HPRD ID		09060	12039
Ensembl ID		ENSG00000160310	ENSG00000137098
Uniprot IDs		B7U630 B7U631 P55345 Q5U7D4	Q99932
PDB IDs		1X2P
Enriched GO Terms of Interacting Partners?		Intracellular Receptor Signaling Pathway Intracellular Steroid Hormone Receptor Signaling Pathway Gene Expression Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway RNA Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Hormone-mediated Signaling Pathway Transcription, DNA-templated Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Cellular Nitrogen Compound Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Response To Steroid Hormone Multicellular Organismal Reproductive Process Reproductive Structure Development Reproductive System Development Multicellular Organism Reproduction Heterocycle Metabolic Process Response To Lipid Cellular Aromatic Compound Metabolic Process Ovulation Cycle Regulation Of Gene Expression Response To Organic Cyclic Compound Reproductive Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Response To Hormone Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Reproduction Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Response To Organic Cyclic Compound Developmental Process Involved In Reproduction Single Organism Reproductive Process Cellular Metabolic Process	Peptidyl-arginine N-methylation Histone Arginine Methylation Peptidyl-arginine Methylation Histone Methylation Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Protein Methylation Chromatin Modification Chromatin Organization Histone Modification Methylation Chromosome Organization Gene Expression Histone H4-R3 Methylation Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Peptidyl-amino Acid Modification Regulation Of RNA Metabolic Process RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Spliceosomal SnRNP Assembly Regulation Of Nitrogen Compound Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nitrogen Compound Metabolic Process Organelle Organization Histone H3-R17 Methylation Cellular Protein Modification Process Ribonucleoprotein Complex Biogenesis Intracellular Steroid Hormone Receptor Signaling Pathway RNA Splicing Regulation Of Metabolic Process Histone H3-R2 Methylation Peptidyl-arginine Methylation, To Symmetrical-dimethyl Arginine Positive Regulation Of Caveolin-mediated Endocytosis Cellular Macromolecule Biosynthetic Process MRNA Processing Macromolecule Biosynthetic Process Ribosomal Small Subunit Export From Nucleus Branchiomeric Skeletal Muscle Development MRNA 5'-splice Site Recognition Regulation Of Growth Plate Cartilage Chondrocyte Proliferation
Tagcloud ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	azoospermia bonferroni cgtg chinese conferred correction crem haplotype idiopathic iplex kif17b maturation noa nonobstructive played polymorphisms protective rs1148247 rs11592356 rs2295415 rs22954152 rs4934540 sequenom seventeen snps spermatogenesis tag tatg variants
Tagcloud (Difference) ?		bbrd brucei clade clades connects dart dihydrolipoamide exemplified fmr homologues methyltransferases outgroup paralogue phylogeny prmt1 prmt3 prmt4 prmt5 prmt6 prmt7 prmt8 prmt9 prmts reconstructing resolve tbprmts tedious trypanosoma uncharacterized	azoospermia bonferroni cgtg chinese conferred correction crem haplotype idiopathic iplex kif17b maturation noa nonobstructive played polymorphisms protective rs1148247 rs11592356 rs2295415 rs22954152 rs4934540 sequenom seventeen snps spermatogenesis tag tatg variants
Tagcloud (Intersection) ?