ZAR1 and DYNLL2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZAR1	DYNLL2
Description		zygote arrest 1	dynein light chain LC8-type 2
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytoplasmic Ribonucleoprotein Granule Intracellular Membraneless Organelle	Nucleus Cytoplasm Centrosome Cytosol Cytoskeleton Cytoplasmic Dynein Complex Microtubule Microtubule Associated Complex Plasma Membrane Cilium Postsynaptic Density Microtubule Cytoskeleton Membrane Dynein Complex Myosin V Complex Ciliary Tip 9+0 Non-motile Cilium Postsynapse Glutamatergic Synapse
	Molecular Function	RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding Zinc Ion Binding Metal Ion Binding RNA Sequestering Activity Molecular Condensate Scaffold Activity	Protein Binding Identical Protein Binding Protein-containing Complex Binding Dynein Intermediate Chain Binding Scaffold Protein Binding
	Biological Process	Oocyte Maturation Translation Negative Regulation Of Translation Cell Differentiation MRNA Stabilization Oogenesis Membraneless Organelle Assembly	Microtubule-based Process
Pathways			Activation of BMF and translocation to mitochondria Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Macroautophagy MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand Intraflagellar transport RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase HCMV Early Events Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Menopause (age at onset) ( 29773799)	Blood protein levels ( 30072576)
Interacting Genes		1 interacting genes: DYNLL2	30 interacting genes: BMF C14orf119 DLGAP1 DNAL4 DPPA3 DYNC1I1 EWSR1 FAM117B GABARAPL2 GPHN GPRIN2 HDAC6 HOMER3 IHO1 MEOX2 MORN3 MYO5A OTUD6A PAK1 PKIA PKIG RASGRP3 REDIC1 SKAP1 SMCP SPAG8 THAP10 TPPP XIAP ZAR1
Entrez ID		326340	140735
HPRD ID		09599	06489
Ensembl ID		ENSG00000182223	ENSG00000264364
Uniprot IDs		B9EG67 Q86SH2	Q96FJ2
PDB IDs			2XQQ 3P8M 4D07 7CNU
Enriched GO Terms of Interacting Partners?		Myosin V Complex 9+0 Non-motile Cilium Dynein Intermediate Chain Binding Cytoplasmic Dynein Complex Microtubule Associated Complex Dynein Complex Ciliary Tip Scaffold Protein Binding Postsynaptic Density Microtubule Cytoskeleton Postsynapse Microtubule Protein-containing Complex Binding	Microtubule Binding
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