HOXD9 and PBX1

Number of citations of the paper that reports this interaction (PMID 10523646)
39

Data Source:
BioGRID (pull down)

		HOXD9	PBX1
Gene Name		homeobox D9	pre-B-cell leukemia homeobox 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Single Fertilization Skeletal Muscle Tissue Development Adult Locomotory Behavior Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Embryonic Forelimb Morphogenesis Hindlimb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Peripheral Nervous System Neuron Development	Branching Involved In Ureteric Bud Morphogenesis Transcription, DNA-templated Steroid Biosynthetic Process Sex Differentiation Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Ossification Adrenal Gland Development Embryonic Limb Morphogenesis Somatic Stem Cell Maintenance Embryonic Hemopoiesis Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Spleen Development Thymus Development Embryonic Skeletal System Development
Pathways			Transcriptional regulation of pluripotent stem cells
Drugs
Diseases
GWAS		Magnesium levels ( 20700443)	Breast cancer (prognosis) ( 23319801) Height ( 20966902)
Protein-Protein Interactions		9 interactors: BARX1 ETV5 FAIM3 GORAB HMGB1 HOXC9 MEIS1 PBX1 PKNOX1	24 interactors: CREBBP HOXA1 HOXA10 HOXA5 HOXA9 HOXB1 HOXB7 HOXB8 HOXD10 HOXD4 HOXD9 KAT2A MDM2 MEIS1 MEIS2 MYH10 NEDD4L NR3C1 PAX6 PBX2 PDX1 PKNOX1 POU2F1 SMARCD3
Entrez ID		3235	5087
HPRD ID		00865	08889
Ensembl ID			ENSG00000185630
Uniprot IDs		P28356	A8K5V0 H0YLB0 P40424 Q53YC7
PDB IDs			1B72 1PUF
Enriched GO Terms of Interacting Partners?		Immune System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune System Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated System Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Anterior/posterior Pattern Specification Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Spleen Development Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Anatomical Structure Development Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Cell Differentiation Gene Expression Developmental Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Cell Clearance Pattern Specification Process Regulation Of Neuron Differentiation Positive Regulation Of Cellular Metabolic Process Skeletal System Development Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Hemopoiesis Generation Of Neurons Regulation Of Neurogenesis Embryonic Skeletal System Development Organ Development Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Neurogenesis Biosynthetic Process Base-excision Repair, DNA Ligation Male Germ-line Stem Cell Asymmetric Division	Transcription, DNA-templated RNA Biosynthetic Process Embryonic Morphogenesis RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Positive Regulation Of Transcription, DNA-templated Anatomical Structure Morphogenesis Pattern Specification Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Anterior/posterior Pattern Specification Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Embryo Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Organ Development Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter Developmental Process Organ Morphogenesis Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Embryonic Skeletal System Development Anatomical Structure Development Embryonic Skeletal System Morphogenesis Regulation Of Metabolic Process Skeletal System Development System Development Chordate Embryonic Development Embryo Development Ending In Birth Or Egg Hatching Embryonic Organ Morphogenesis Proximal/distal Pattern Formation Skeletal System Morphogenesis Embryonic Limb Morphogenesis Embryonic Organ Development Negative Regulation Of Myeloid Cell Differentiation
Tagcloud ?		aberrantly aberration adjacent autosomal beadchips bisulfite cholangiocarcinogenesis cholangiocarcinoma cpg eed epigenetically epigenomic false homeobox hoxa9 humanmethylation27 hypermethylated hypermethylation hypomethylated infinium methylomes ontology prc2 profiled pyrosequencing representing sets suz12 trimethylation	4th addressed alls bmt bristol characterizing clonospecific confirmation cure dek e2a igh immunoglobulin issues leukaemia lymphoblastic myelogenous offers opportunity presumably purposes quantitate rara rearrangements tcr took truly uk workshop
Tagcloud (Difference) ?		aberrantly aberration adjacent autosomal beadchips bisulfite cholangiocarcinogenesis cholangiocarcinoma cpg eed epigenetically epigenomic false homeobox hoxa9 humanmethylation27 hypermethylated hypermethylation hypomethylated infinium methylomes ontology prc2 profiled pyrosequencing representing sets suz12 trimethylation	4th addressed alls bmt bristol characterizing clonospecific confirmation cure dek e2a igh immunoglobulin issues leukaemia lymphoblastic myelogenous offers opportunity presumably purposes quantitate rara rearrangements tcr took truly uk workshop
Tagcloud (Intersection) ?