HOXD9 and BARX1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		HOXD9	BARX1
Description		homeobox D9	BARX homeobox 1
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nucleolus	Chromatin Nucleus
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Single Fertilization Skeletal Muscle Tissue Development Adult Locomotory Behavior Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Regulation Of Gene Expression Mammary Gland Development Embryonic Forelimb Morphogenesis Forelimb Morphogenesis Hindlimb Morphogenesis Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Embryonic Skeletal System Development Peripheral Nervous System Neuron Development	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Cell-cell Signaling Tissue Development Anterior/posterior Pattern Specification Wnt Signaling Pathway Negative Regulation Of Wnt Signaling Pathway Endothelial Cell Differentiation Animal Organ Development Spleen Development Digestive System Development
Pathways
Drugs
Diseases
GWAS		Estimated glomerular filtration rate ( 31015462) Magnesium levels ( 20700443) Male-pattern baldness ( 28196072)	Barrett's esophagus ( 24121790) Digestive system disease (Barrett's esophagus and esophageal adenocarcinoma combined) ( 24121790) Esophageal adenocarcinoma ( 24121790) Heel bone mineral density ( 28869591) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Parkinson's disease ( 26227905) Serum folate levels ( 29953918)
Interacting Genes		9 interacting genes: BARX1 ETV5 FCMR GORAB HMGB1 HOXC9 MEIS1 PBX1 PKNOX1	5 interacting genes: CYP17A1 HOXD9 MAPK6 RPS6KA3 UBC
Entrez ID		3235	56033
HPRD ID		00865	16017
Ensembl ID		ENSG00000128709	ENSG00000131668
Uniprot IDs		P28356	Q9HBU1
PDB IDs			2DMT
Enriched GO Terms of Interacting Partners?		Eye Development Sensory Organ Development Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity DNA Binding Regulation Of Transcription By RNA Polymerase II Pattern Specification Process Sequence-specific DNA Binding Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Hemopoiesis Regulation Of Neuron Differentiation Sequence-specific Double-stranded DNA Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Spleen Development Transcription Regulator Complex Lymphocyte Differentiation Transcription Cis-regulatory Region Binding Regulation Of RNA Metabolic Process Regionalization Embryonic Skeletal System Development Animal Organ Development Developmental Process Regulation Of Nucleobase-containing Compound Metabolic Process Mononuclear Cell Differentiation Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Transcription Repressor Complex Positive Regulation Of Myeloid Progenitor Cell Differentiation High-affinity IgM Receptor Activity Negative Regulation Of Neuron Differentiation RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Cell Development Positive Regulation Of Cell Population Proliferation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Leukocyte Differentiation Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Negative Regulation Of Apoptotic Cell Clearance RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Polymeric Immunoglobulin Binding Cellular Developmental Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of RNA Metabolic Process DNA-templated Transcription Hematopoietic Or Lymphoid Organ Development Male Germ-line Stem Cell Asymmetric Division
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