HOXD8 and ANXA7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		HOXD8	ANXA7
Gene Name		homeobox D8	annexin A7
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Chromaffin Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription	Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Anterior/posterior Axis Specification, Embryo Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Morphogenesis	Cellular Calcium Ion Homeostasis Autophagy Hemostasis Cell Proliferation Regulation Of Cell Shape Response To Salt Stress Cellular Water Homeostasis Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Social Behavior Response To Calcium Ion Membrane Fusion
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ANXA7 CDKN1A HMGB1 PFDN1 RCC1	108 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CPSF3L CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TP53 TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		3234	310
HPRD ID		00868	01720
Ensembl ID		ENSG00000175879	ENSG00000138279
Uniprot IDs		F8VSA3 P13378	B2R657 P20073
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apoptotic Cell Clearance Regulation Of Cellular Component Organization Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Base-excision Repair, DNA Ligation Intestinal Epithelial Cell Maturation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Response To UV-B Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Negative Regulation Of Gene Expression Cell Cycle Positive Regulation Of Ran GTPase Activity DNA Ligation Involved In DNA Repair Stress-induced Premature Senescence Regulation Of Apoptotic Cell Clearance Negative Regulation Of Phagocytosis Positive Regulation Of Catalytic Activity Cellular Water Homeostasis Regulation Of Mitotic Cell Cycle DNA Ligation Dendritic Cell Chemotaxis Regulation Of Metabolic Process Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development Regulation Of Protein Import Into Nucleus, Translocation Apoptotic DNA Fragmentation Leukocyte Activation Regulation Of Cell Cycle Process Intestinal Epithelial Cell Differentiation Epithelial Cell Maturation Regulation Of DNA-templated Transcription, Initiation Epithelial Cell Differentiation Dendritic Cell Migration Response To Arsenic-containing Substance Myeloid Dendritic Cell Activation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Chemotaxis Positive Regulation Of Programmed Cell Death V(D)J Recombination Cellular Senescence Positive Regulation Of Cell Death Apoptotic Nuclear Changes Cell Volume Homeostasis Immune System Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray	Anatomical Structure Development Multicellular Organismal Development Developmental Process System Development Cellular Metabolic Process Metabolic Process Cellular Response To Organic Substance Platelet Activation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Cellular Protein Metabolic Process Blood Coagulation Response To Growth Factor Programmed Cell Death Hemostasis Negative Regulation Of Cellular Protein Metabolic Process Cell Death Catabolic Process Death Response To Organic Substance Apoptotic Process Histone H3-T6 Phosphorylation Regulation Of Apoptotic Process Nervous System Development Regulation Of Body Fluid Levels Negative Regulation Of Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Negative Regulation Of Glucose Transport Organelle Organization Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Catalytic Activity Cellular Process Regulation Of Cellular Response To Insulin Stimulus Wound Healing Cellular Response To Stimulus Regulation Of Proteasomal Protein Catabolic Process Gene Expression Protein Metabolic Process Mitotic Cell Cycle Organ Development Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization
Tagcloud ?		chip deep dysregulated dysregulation h3k27me3 homeobox hoxb7 hoxc10 hoxc13 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tshz3 tumorigenic	annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Difference) ?		chip deep dysregulated dysregulation h3k27me3 homeobox hoxb7 hoxc10 hoxc13 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tshz3 tumorigenic	annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Intersection) ?