HOXD8 and ANXA7

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		HOXD8	ANXA7
Description		homeobox D8	annexin A7
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Nucleus Cytoplasm Endoplasmic Reticulum Membrane Plasma Membrane Vesicle Membrane Membrane Extracellular Matrix Chromaffin Granule Membrane Extracellular Exosome
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific Double-stranded DNA Binding	Phosphatidylserine Binding RNA Binding Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Calcium-dependent Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anterior/posterior Axis Specification, Embryo Anterior/posterior Pattern Specification Positive Regulation Of Transcription By RNA Polymerase II Skeletal System Morphogenesis	Autophagy Negative Regulation Of Gene Expression Epithelial Cell Differentiation Response To Calcium Ion Membrane Fusion Response To Phorbol 13-acetate 12-myristate
Pathways
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 31152163) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 30604766 31015462 31152163) Glomerular filtration rate (creatinine) ( 28452372) Male-pattern baldness ( 28196072) Urate levels ( 31578528)	Copper levels ( 26025379)
Interacting Genes		8 interacting genes: ANXA7 BAIAP2 CDKN1A HMGB1 LDLRAP1 NCK2 PFDN1 RCC1	109 interacting genes: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5F1B ATP6V1A ATXN3 BAG6 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CREBBP CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 ERG28 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 HUNK INPP5K INTS11 KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OGT OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS1 RBBP4 RBM48 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		3234	310
HPRD ID		00868	01720
Ensembl ID		ENSG00000175879	ENSG00000138279
Uniprot IDs		A0A0A0MSX5 P13378	B2R657 P20073
PDB IDs			8W5S
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation Cytoskeletal Anchor Activity Positive Regulation Of Leukocyte Proliferation Signaling Receptor Complex Adaptor Activity Vesicle Membrane Cytoplasm Regulation Of Leukocyte Proliferation Regulation Of Mononuclear Cell Proliferation Phosphotyrosine Residue Binding Positive Regulation Of Actin Filament Polymerization Phosphatidylserine Binding Positive Regulation Of Lymphocyte Activation Positive Regulation Of Cell Population Proliferation PCNA-p21 Complex Cell Cycle G1/S Phase Transition Negative Regulation Of Cardiac Muscle Tissue Regeneration G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Cell Activation Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Negative Regulation Of RNA Polymerase II Transcription Preinitiation Complex Assembly Positive Regulation Of Myeloid Progenitor Cell Differentiation Negative Regulation Of Apoptotic Cell Clearance Regulation Of Supramolecular Fiber Organization Amyloid-beta Binding Positive Regulation Of Protein Polymerization Signaling Adaptor Activity Scaffold Protein Binding Dendritic Spine Cytoplasm Neuron Projection Branch Point Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport Receptor-mediated Endocytosis Involved In Cholesterol Transport Regulation Of Protein-containing Complex Assembly Positive Regulation Of T Cell Proliferation C-X-C Chemokine Binding Alphav-beta3 Integrin-HMGB1 Complex T-helper 1 Cell Activation Positive Regulation Of Mismatch Repair Positive Regulation Of Intracellular Cholesterol Transport Regulation Of Lymphocyte Activation Cellular Response To Cell-matrix Adhesion Regulation Of Mismatch Repair Plasmacytoid Dendritic Cell Activation Regulation Of Myeloid Progenitor Cell Differentiation Positive Regulation Of Glycogen Catabolic Process Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress	TORC1 Signaling Extracellular Exosome TOR Signaling Negative Regulation Of TOR Signaling Negative Regulation Of TORC1 Signaling Regulation Of TORC1 Signaling Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Regulation Of TOR Signaling Positive Regulation Of Metabolic Process Positive Regulation Of TORC1 Signaling Positive Regulation Of Macromolecule Metabolic Process Regulation Of Stem Cell Population Maintenance Cytoplasm Regulation Of Primary Metabolic Process Protein Modification By Small Protein Removal Extracellular Matrix Positive Regulation Of Biosynthetic Process Positive Regulation Of TOR Signaling Developmental Process Regulation Of Metabolic Process Macromolecule Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Perinuclear Region Of Cytoplasm Regulation Of Protein Metabolic Process Protein Deubiquitination Cellular Response To Nutrient Levels Regulation Of Proteolysis Histone H3T6 Kinase Activity Structural Constituent Of Cytoskeleton Positive Regulation Of Protein Metabolic Process Platelet Alpha Granule Lumen Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Protein Metabolic Process Blood Microparticle Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Protein Catabolic Process Cytoplasmic Translation Diacylglycerol-dependent Serine/threonine Kinase Activity Cytosol Nuclear Matrix Response To Interleukin-1 Response To Cytokine Regulation Of Protein Localization Negative Regulation Of Signal Transduction Calyx Of Held Negative Regulation Of Translational Initiation Protein Kinase C Signaling Proteasomal Protein Catabolic Process
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