HOXC8 and HOMEZ

Number of citations of the paper that reports this interaction (PMID 12925734)
5

Data Source:
HPRD (two hybrid)

		HOXC8	HOMEZ
Gene Name		homeobox C8	homeobox and leucine zipper encoding
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Microtubule Cytoskeleton	Nucleus Nucleolus Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Sequence-specific DNA Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Anterior/posterior Pattern Specification Neuron Differentiation Skeletal System Morphogenesis	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: BMPR1A BTG2 DLX2 DLX5 GMNN HOMEZ JUN MSX1 SMAD1 SMAD4 SMAD6	31 interactors: AEN AES APITD1 DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPL9 SDCBP SH3RF2 SMYD1 SNRPB2 SUMO2 TCEB3 TRAF4 ZBTB7A
Entrez ID		3224	57594
HPRD ID		00856	12167
Ensembl ID			ENSG00000215271
Uniprot IDs		P31273	F8WCA3 Q8IX15
PDB IDs			2ECC 2YS9
Enriched GO Terms of Interacting Partners?		BMP Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Pattern Specification Process Transforming Growth Factor Beta Receptor Signaling Pathway Tissue Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Response To Transforming Growth Factor Beta Stimulus Organ Development Regulation Of RNA Metabolic Process Response To Transforming Growth Factor Beta Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cell Proliferation Regulation Of Gene Expression Endocardial Cushion Formation Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Organ Morphogenesis Endocardial Cushion Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Growth Factor Stimulus Response To Growth Factor Epithelium Development Palate Development Embryonic Morphogenesis Embryo Development Negative Regulation Of Cell Proliferation System Development Endocardial Cushion Development Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Head Development RNA Metabolic Process Nervous System Development Multicellular Organismal Development Cell Differentiation Gene Expression Anatomical Structure Development Cartilage Development Generation Of Neurons Regulation Of Cell Differentiation	Regulation Of Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Response To Ionizing Radiation RNA Metabolic Process Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Energy Homeostasis Positive Regulation Of Glycolytic Process Negative Regulation Of Cellular Metabolic Process Fatty Acid Homeostasis Biosynthetic Process Histone-serine Phosphorylation Positive Regulation Of Metabolic Process Cellular Response To Glucose Starvation Regulation Of Glycolytic Process Regulation Of Cellular Process Chromatin Modification Negative Regulation Of TOR Signaling Protein Modification By Small Protein Conjugation Regulation Of MAPK Cascade Histone Exchange Cholesterol Biosynthetic Process Insulin Receptor Signaling Pathway Positive Regulation Of Autophagy Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Biosynthetic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Histone Phosphorylation Translational Elongation Histone Modification Sterol Biosynthetic Process Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Regulation Of RNA Metabolic Process Anion Homeostasis Chromatin Remodeling
Tagcloud ?		abrogates cdkn1b correlates cyclophilin33 cyp33 downregulation h3k4me3 h4 homeodomain hoxa9 implying isomerase lineage lost mediates mll mutually phd3 preferentially proline reinsertion repression rrm selectivity structurally switch transforming translocations trimethylated
Tagcloud (Difference) ?		abrogates cdkn1b correlates cyclophilin33 cyp33 downregulation h3k4me3 h4 homeodomain hoxa9 implying isomerase lineage lost mediates mll mutually phd3 preferentially proline reinsertion repression rrm selectivity structurally switch transforming translocations trimethylated
Tagcloud (Intersection) ?