EHD2 and BPGM

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		EHD2	BPGM
Gene Name		EH-domain containing 2	2,3-bisphosphoglycerate mutase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Caveola Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Vesicular Exosome	Extracellular Vesicular Exosome
	Molecular Function	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding	Bisphosphoglycerate Mutase Activity Bisphosphoglycerate 2-phosphatase Activity Phosphoglycerate Mutase Activity
	Biological Process	Endocytosis Blood Coagulation Metabolic Process Cortical Actin Cytoskeleton Organization Endocytic Recycling Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling	Carbohydrate Metabolic Process Glycolytic Process Respiratory Gaseous Exchange Dephosphorylation Erythrocyte Development
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AP1M1 AP1M2 AP2M1 BPGM DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23	9 interactors: AKT1 ATF6 ATP4B CEL EGR2 EHD2 GAPDH GRB2 NEK3
Entrez ID		30846	669
HPRD ID		10434	01961
Ensembl ID		ENSG00000024422	ENSG00000172331
Uniprot IDs		Q9NZN4	P07738
PDB IDs			1T8P 2A9J 2F90 2H4X 2H4Z 2H52 2HHJ 3NFY
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus Membrane Organization Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cell Differentiation Clathrin-mediated Endocytosis Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Vesicle-mediated Transport Antigen Processing And Presentation Intracellular Transport Amylopectin Biosynthetic Process Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Intracellular Protein Transport Developmental Process Post-Golgi Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Establishment Of Localization In Cell Viral Process Immune System Process Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Synaptic Transmission Cellular Protein Localization Cargo Loading Into Vesicle Protein Transport Cellular Localization Iron Ion Import Into Cell Establishment Of Protein Localization Regulation Of Endocytosis DNA Methylation Involved In Embryo Development Establishment Of Vesicle Localization Vesicle Organization Pigment Granule Maturation Endosome To Melanosome Transport Glucose Import Endosomal Transport Vesicle Localization Dendritic Spine Maintenance Cellular Pigment Accumulation Synaptic Vesicle Maturation Positive Regulation Of Beta-amyloid Formation Neuronal Ion Channel Clustering Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Iron Ion Import Negative Regulation Of Actin Nucleation	Regulation Of Body Fluid Levels Response To Organic Substance Response To Insulin Response To Organonitrogen Compound Labyrinthine Layer Development Schwann Cell Differentiation Cellular Response To Organic Substance T Cell Costimulation Rhombomere 5 Formation Rhombomere 3 Formation Glycogen Cell Differentiation Involved In Embryonic Placenta Development Peptidyl-cysteine S-trans-nitrosylation Protein Esterification Intestinal Lipid Catabolic Process Blood Coagulation Hemostasis Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide Peripheral Nervous System Development Rhombomere 3 Morphogenesis Embryonic Placenta Development Cellular Response To Hormone Stimulus Brain Segmentation Multicellular Organismal Lipid Catabolic Process Phosphatidylinositol-mediated Signaling Wound Healing Glucose Metabolic Process Myelination Axon Ensheathment Insulin Receptor Signaling Pathway Carbohydrate Biosynthetic Process Rhombomere 3 Development Rhombomere 5 Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Regulation Of Reactive Oxygen Species Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Rhombomere Morphogenesis Peptidyl-cysteine S-nitrosylation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Response To Wounding Cellular Protein Metabolic Process Glial Cell Differentiation Response To UV-A Cellular Response To Fibroblast Growth Factor Stimulus
Tagcloud ?		acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly	biphosphoglycerate congenital csf3r epo epor erythrocytosis erythropoietin exhibit gelsolin germline haemoglobin hereditary inheritance inherited mendelian mpl mutase mutational myeloproliferative neutrophilia oxygen pedigrees sensing syndromes thpo thrombocytosis thrombopoietin uncovered v617f
Tagcloud (Difference) ?		acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome unexpectedly	biphosphoglycerate congenital csf3r epo epor erythrocytosis erythropoietin exhibit gelsolin germline haemoglobin hereditary inheritance inherited mendelian mpl mutase mutational myeloproliferative neutrophilia oxygen pedigrees sensing syndromes thpo thrombocytosis thrombopoietin v617f
Tagcloud (Intersection) ?		uncovered