EHD2 and RBSN

Number of citations of the paper that reports this interaction (PMID 15020713)
49

Data Source:
BioGRID (two hybrid)

		EHD2	RBSN
Gene Name		EH-domain containing 2	rabenosyn, RAB effector
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Caveola Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Vesicular Exosome	Endosome Plasma Membrane Endosome Membrane Cytoplasmic Side Of Endosome Membrane Early Endosome Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding	Protein Binding Zinc Ion Binding Rab GTPase Binding
	Biological Process	Endocytosis Blood Coagulation Metabolic Process Cortical Actin Cytoskeleton Organization Endocytic Recycling Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling	Vacuole Inheritance Golgi To Endosome Transport Golgi To Vacuole Transport Endocytosis Blood Coagulation Protein Transport Endosomal Transport Endosomal Vesicle Fusion Late Endosome To Vacuole Transport
Pathways		Factors involved in megakaryocyte development and platelet production	Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: AP1M1 AP1M2 AP2M1 BPGM DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23	13 interactors: DISC1 DTNBP1 EHD1 EHD2 EHD3 MAPK14 RAB14 RAB24 RAB2A RAB4A RAB5A RAB5C VPS45
Entrez ID		30846	64145
HPRD ID		10434	15732
Ensembl ID		ENSG00000024422	ENSG00000131381
Uniprot IDs		Q9NZN4	Q9H1K0
PDB IDs			1YZM 1Z0J 1Z0K
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus Membrane Organization Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cell Differentiation Clathrin-mediated Endocytosis Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Vesicle-mediated Transport Antigen Processing And Presentation Intracellular Transport Amylopectin Biosynthetic Process Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Intracellular Protein Transport Developmental Process Post-Golgi Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Establishment Of Localization In Cell Viral Process Immune System Process Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Synaptic Transmission Cellular Protein Localization Cargo Loading Into Vesicle Protein Transport Cellular Localization Iron Ion Import Into Cell Establishment Of Protein Localization Regulation Of Endocytosis DNA Methylation Involved In Embryo Development Establishment Of Vesicle Localization Vesicle Organization Pigment Granule Maturation Endosome To Melanosome Transport Glucose Import Endosomal Transport Vesicle Localization Dendritic Spine Maintenance Cellular Pigment Accumulation Synaptic Vesicle Maturation Positive Regulation Of Beta-amyloid Formation Neuronal Ion Channel Clustering Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Iron Ion Import Negative Regulation Of Actin Nucleation See more	Rab Protein Signal Transduction Cellular Protein Localization Intracellular Protein Transport Intracellular Transport Ras Protein Signal Transduction Cellular Localization Protein Localization Establishment Of Localization In Cell Protein Transport Endocytic Recycling Establishment Of Protein Localization Endosomal Transport Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Small GTPase Mediated Signal Transduction Response To Wounding Positive Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Myoblast Fusion Vesicle-mediated Transport Positive Regulation Of Myotube Differentiation Positive Regulation Of Endocytic Recycling Regulation Of Vesicle-mediated Transport Response To Stimulus Intracellular Signal Transduction Transport Regulation Of Endocytic Recycling Regulation Of Myotube Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Cardiac Muscle Cell Membrane Potential Positive Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Regulation Of Cellular Component Organization Positive Regulation Of Transport Membrane Organization Regulation Of Muscle Cell Differentiation Endomembrane System Organization Regulation Of Endocytosis Regulation Of Cellular Localization Protein Targeting To Plasma Membrane Positive Regulation Of Intracellular Transport Endocytosis Protein Homooligomerization P38MAPK Cascade Phagolysosome Assembly Involved In Apoptotic Cell Clearance Regulation Of Neurotransmitter Secretion Signaling Cell Communication See more
Tagcloud ?		acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly
Tagcloud (Difference) ?		acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly
Tagcloud (Intersection) ?