EHD2 and EHBP1

Number of citations of the paper that reports this interaction (PMID 14676205)
39

Data Source:
HPRD (in vivo, in vitro)

		EHD2	EHBP1
Gene Name		EH-domain containing 2	EH domain binding protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Caveola Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Vesicular Exosome	Cytoplasm Plasma Membrane
	Molecular Function	Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding
	Biological Process	Endocytosis Blood Coagulation Metabolic Process Cortical Actin Cytoskeleton Organization Endocytic Recycling Protein Localization To Plasma Membrane Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Crohn's disease ( 22412388) Prostate cancer ( 18264098 19767753)
Protein-Protein Interactions		13 interactors: AP1M1 AP1M2 AP2M1 BPGM DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23	3 interactors: EHD1 EHD2 PACSIN1
Entrez ID		30846	23301
HPRD ID		10434	10109
Ensembl ID		ENSG00000024422	ENSG00000115504
Uniprot IDs		Q9NZN4	A8K930 Q8NDI1
PDB IDs			2D89
Enriched GO Terms of Interacting Partners?		Regulation Of Defense Response To Virus By Virus Membrane Organization Regulation Of Defense Response To Virus Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Cell Differentiation Clathrin-mediated Endocytosis Antigen Processing And Presentation Of Peptide Antigen Golgi Vesicle Transport Vesicle-mediated Transport Antigen Processing And Presentation Intracellular Transport Amylopectin Biosynthetic Process Positive Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Intracellular Protein Transport Developmental Process Post-Golgi Vesicle-mediated Transport Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Establishment Of Localization In Cell Viral Process Immune System Process Regulation Of Aspartic-type Endopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Negative Regulation Of Metalloendopeptidase Activity Involved In Amyloid Precursor Protein Catabolic Process Synaptic Transmission Cellular Protein Localization Cargo Loading Into Vesicle Protein Transport Cellular Localization Iron Ion Import Into Cell Establishment Of Protein Localization Regulation Of Endocytosis DNA Methylation Involved In Embryo Development Establishment Of Vesicle Localization Vesicle Organization Pigment Granule Maturation Endosome To Melanosome Transport Glucose Import Endosomal Transport Vesicle Localization Dendritic Spine Maintenance Cellular Pigment Accumulation Synaptic Vesicle Maturation Positive Regulation Of Beta-amyloid Formation Neuronal Ion Channel Clustering Negative Regulation Of Amyloid Precursor Protein Catabolic Process Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Iron Ion Import Negative Regulation Of Actin Nucleation	Positive Regulation Of Endocytic Recycling Regulation Of Endocytic Recycling Positive Regulation Of Myoblast Fusion Regulation Of Myoblast Fusion Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Endocytic Recycling Regulation Of Vesicle-mediated Transport Positive Regulation Of Myotube Differentiation Regulation Of Myotube Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Endocytosis Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Muscle Cell Differentiation Regulation Of Striated Muscle Cell Differentiation Positive Regulation Of Cell Differentiation Regulation Of Muscle Cell Differentiation Protein Localization To Plasma Membrane Cellular Protein Localization Endosomal Transport Vesicle-mediated Transport Establishment Of Protein Localization Plasma Membrane Organization Establishment Of Protein Localization To Membrane Positive Regulation Of Intracellular Transport Regulation Of Cell Differentiation Protein Homooligomerization Protein Localization Regulation Of Cellular Component Organization Establishment Of Localization In Cell Protein Localization To Membrane Blood Coagulation Hemostasis Protein Oligomerization Regulation Of Intracellular Transport Endomembrane System Organization Regulation Of Cardiac Muscle Cell Membrane Potential Cellular Localization Positive Regulation Of Cholesterol Storage Regulation Of Body Fluid Levels Wound Healing Actin Cytoskeleton Organization Actin Filament-based Process Membrane Tubulation Low-density Lipoprotein Particle Clearance Response To Wounding Cellular Response To Nerve Growth Factor Stimulus Positive Regulation Of Transport Cortical Actin Cytoskeleton Organization Neuron Projection Development Positive Regulation Of Lipid Storage
Tagcloud ?		acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly	bcrp c9orf3 cassette cdyl chemotherapeutics chemotherapies conferred ctrl devised dock farnesol farnesylation farnesyltransferase foxa2 functionalized ine1 isoprenoid lmo7 mdr1 mrp1 mrs2 neb numbl oils oncoproteins pharmacogenomic sesquiterpene stab2 urgently
Tagcloud (Difference) ?		acted adapter converts cytoplasm cytoskeleton deprived deregulated direction e2 enrichment fhl2 homer3 hydroxytamoxifen mcf modulator oestrogen oht organelle overlap pf rationale remarkable remodelling reorganisation reprogrammed rhof transcriptome uncovered unexpectedly	bcrp c9orf3 cassette cdyl chemotherapeutics chemotherapies conferred ctrl devised dock farnesol farnesylation farnesyltransferase foxa2 functionalized ine1 isoprenoid lmo7 mdr1 mrp1 mrs2 neb numbl oils oncoproteins pharmacogenomic sesquiterpene stab2 urgently
Tagcloud (Intersection) ?