EHD2 and EHBP1

Number of citations of the paper that reports this interaction (PubMedID 14676205)
0

Data Source:
HPRD (in vitro, in vivo)

		EHD2	EHBP1
Description		EH domain containing 2	EH domain binding protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Caveola Endosome Membrane Membrane Endocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Membrane Extracellular Exosome	Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Nucleic Acid Binding Calcium Ion Binding Protein Binding ATP Binding GTP Binding Hydrolase Activity Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Endocytosis Cortical Actin Cytoskeleton Organization Endocytic Recycling Cilium Assembly Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Myoblast Fusion Positive Regulation Of Endocytic Recycling	Endocytosis Protein Transport
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS			Apolipoprotein B levels ( 32203549) Body mass index ( 25673413 28892062) Coffee consumption ( 31046077) Coronary artery disease ( 33020668 29212778) Crohn's disease ( 22412388) Fruit consumption ( 32066663) Haemorrhoidal disease ( 33888516) LDL cholesterol ( 24097068 30275531) LDL cholesterol levels ( 28334899 32203549 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Low density lipoprotein cholesterol levels ( 32154731 33339817) Myocardial infarction ( 33532862) Prostate cancer ( 18264098 25939597 19767753) Regular attendance at a religious group ( 29970889) Total cholesterol levels ( 29403010 33339817)
Interacting Genes		14 interacting genes: AP1M1 AP1M2 AP2M1 BPGM CDC42 DDX56 EHBP1 PICALM PICK1 RBSN SLC2A4 SPATA24 TAGLN2 TBC1D23	3 interacting genes: EHD1 EHD2 PACSIN1
Entrez ID		30846	23301
HPRD ID		10434	10109
Ensembl ID		ENSG00000024422	ENSG00000115504
Uniprot IDs		Q9NZN4	A0A140VK17 A8K930 Q8NDI1
PDB IDs			2D89 6ZSH 6ZSI 6ZSJ
Enriched GO Terms of Interacting Partners?		Cytosol Intracellular Transport Clathrin Adaptor Complex Cellular Localization Establishment Of Localization In Cell Clathrin Adaptor Activity Clathrin-coated Vesicle Vesicle-mediated Transport Extrinsic Component Of Presynaptic Endocytic Zone Membrane Protein Transport Intracellular Protein Localization Clathrin-coated Pit Establishment Of Protein Localization AP-1 Adaptor Complex Intracellular Protein Transport Regulation Of Endocytosis Regulation Of Vesicle Size Trans-Golgi Network Membrane Regulation Of Receptor-mediated Endocytosis Clathrin-coated Endocytic Vesicle Synaptic Vesicle Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Receptor Internalization Negative Regulation Of Protein Localization To Plasma Membrane Positive Regulation Of Endocytosis Clathrin-dependent Endocytosis Dendritic Spine Organization Vesicle Budding From Membrane Cytoplasmic Vesicle Membrane Endocytosis Clathrin-coated Vesicle Membrane Vesicle Cytoplasmic Vesicle Extracellular Exosome Neuron Projection Organization Postsynapse Organization Regulation Of Vesicle-mediated Transport Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Positive Regulation Of Receptor-mediated Endocytosis Endosomal Transport Import Into Cell Membrane Organization Receptor Internalization GBD Domain Binding Storage Vacuole Endocytic Vesicle Membrane Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway Regulation Of Receptor Internalization	Positive Regulation Of Endocytic Recycling Protein Localization To Plasma Membrane Regulation Of Myoblast Fusion Regulation Of Endocytic Recycling Protein Localization To Cell Periphery Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Positive Regulation Of Myoblast Fusion Plasma Membrane Tubulation Cilium Assembly Cell Projection Organization Cilium Organization Protein Localization To Membrane Plasma Membrane Bounded Cell Projection Assembly Cell Projection Assembly Cellular Localization Establishment Of Localization In Cell Endocytosis Endocytic Vesicle Localization Within Membrane Endocytic Recycling Regulation Of Vesicle-mediated Transport Import Into Cell Regulation Of Plasma Membrane Bounded Cell Projection Organization Recycling Endosome Membrane Regulation Of Cell Projection Organization Presynaptic Endocytic Zone Axonemal Basal Plate Perinuclear Region Of Cytoplasm Organelle Assembly Plasma Membrane Organization Endosome Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Intracellular Transport Regulation Of Developmental Process Regulation Of Cellular Component Organization Organelle Organization Positive Regulation Of Neuron Projection Development Regulation Of Embryonic Cell Shape Plasma Membrane Bounded Cell Projection Organization Ciliary Pocket Membrane Cytoskeleton Organization Protein-macromolecule Adaptor Activity Positive Regulation Of Cellular Component Organization Vesicle-mediated Transport Septin Cytoskeleton Organization Tongue Morphogenesis Intracellular Transport Endosomal Transport Regulation Of Intracellular Transport Cell Projection
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