ZNRD1 and IVNS1ABP

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ZNRD1	IVNS1ABP
Gene Name		zinc ribbon domain containing 1	influenza virus NS1A binding protein
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm DNA-directed RNA Polymerase I Complex	Nucleoplasm Transcription Factor Complex Spliceosomal Complex Cytoplasm Actin Cytoskeleton
	Molecular Function	RNA Polymerase I Activity Nucleic Acid Binding Zinc Ion Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Gene Expression Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic	Transcription From RNA Polymerase III Promoter RNA Splicing Response To Virus Viral Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Chain Elongation RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape RNA Polymerase I Promoter Clearance Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression
Drugs
Diseases
GWAS		AIDS progression ( 19115949) HIV-1 control ( 20041166)
Protein-Protein Interactions		15 interactors: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP NONO SACS SERPINA3 UBE2I ZNF593	8 interactors: AHR CHD3 PFN2 RPL6 SYNCRIP TRA2B VIM ZNRD1
Entrez ID		30834	10625
HPRD ID		09601	10004
Ensembl ID		ENSG00000066379	ENSG00000116679
Uniprot IDs		Q2L6J2 Q9P1U0	A8MVR0 Q9Y6Y0
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Protein Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Intracellular Signal Transduction Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Extrathymic T Cell Selection Negative Regulation Of Cell Adhesion Molecule Production Positive Regulation Of SUMO Transferase Activity Regulation Of Signal Transduction Negative Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Interleukin-1 Beta Secretion Regulation Of Signaling Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Cholesterol Import NK T Cell Proliferation Negative Regulation Of Intracellular Signal Transduction Regulation Of Protein Targeting To Mitochondrion Negative Regulation Of Interleukin-1 Secretion Alpha-beta T Cell Proliferation Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Cellular Ketone Metabolic Process Regulation Of Protein Phosphorylation Skeletal Muscle Atrophy High-density Lipoprotein Particle Clearance Negative Regulation Of Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Natural Killer Cell Proliferation Striated Muscle Atrophy Protein Oxidation Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Gene Expression Regulation Of Natural Killer Cell Proliferation Muscle Atrophy Negative Regulation Of Cytokine Secretion Involved In Immune Response Negative Regulation Of Heterotypic Cell-cell Adhesion High-density Lipoprotein Particle Assembly Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Signaling Regulation Of Cellular Component Organization Negative Regulation Of Oxidative Stress-induced Neuron Death Positive Regulation Of Granulocyte Differentiation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway	Regulation Of Metabolic Process Regulation Of Gene Expression RNA Metabolic Process Gene Expression MRNA Metabolic Process Viral Process Negative Regulation Of Cell Projection Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Protein Complex Assembly Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly CRD-mediated MRNA Stabilization Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Ruffle Assembly Bergmann Glial Cell Differentiation Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Component Biogenesis Cytoskeleton Organization Regulation Of Protein Complex Assembly RNA Biosynthetic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter RNA Splicing Positive Regulation Of DNA-templated Transcription, Initiation Regulation Of Ruffle Assembly Intermediate Filament Organization Lens Fiber Cell Development
Tagcloud ?		acceleration angiogenesis arrest block cdk2 cdk4 cip1 controlling cytostatic densities dephosphorylation differentially fragmentary gastric instability kip1 microarray microvessel mkn28 p27 pivotal prb precise ribbon sense skp2 suppressed waf1 zinc	11q 13q 14q 15q 1q 21q 22q 2q 3q 4p 4q 9q acgh acsl1 atp8b4 bcl1 fbxl5 imbalances irf2bp2 jh lamp2 myeloma nampt picalm q13 q32 samsn1 stk17b xq
Tagcloud (Difference) ?		acceleration angiogenesis arrest block cdk2 cdk4 cip1 controlling cytostatic densities dephosphorylation differentially fragmentary gastric instability kip1 microarray microvessel mkn28 p27 pivotal prb precise ribbon sense skp2 suppressed waf1 zinc	11q 13q 14q 15q 1q 21q 22q 2q 3q 4p 4q 9q acgh acsl1 atp8b4 bcl1 fbxl5 imbalances irf2bp2 jh lamp2 myeloma nampt picalm q13 q32 samsn1 stk17b xq
Tagcloud (Intersection) ?