POLR1H and GPR20

Number of citations of the paper that reports this interaction (PubMedID 21988832)
38

Data Source:
BioGRID (two hybrid)

		POLR1H	GPR20
Description		RNA polymerase I subunit H	G protein-coupled receptor 20
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GO Annotations	Cellular Component	DNA-directed RNA Polymerase Complex Nucleus Nucleoplasm Nucleolus RNA Polymerase I Complex	Plasma Membrane Membrane Receptor Complex
	Molecular Function	Nucleic Acid Binding DNA-directed RNA Polymerase Activity Protein Binding Zinc Ion Binding Metal Ion Binding	G Protein-coupled Receptor Activity
	Biological Process	Nucleobase-containing Compound Metabolic Process DNA-templated Transcription Termination Of RNA Polymerase I Transcription	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways		NoRC negatively regulates rRNA expression B-WICH complex positively regulates rRNA expression RNA Polymerase I Transcription Initiation RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Escape RNA Polymerase I Transcription Termination	G alpha (s) signalling events
Drugs
Diseases
GWAS			Bipolar disorder ( 21926972) Birth weight ( 31043758) Blood pressure traits (multi-trait analysis) ( 28498854) Diastolic blood pressure ( 27618447 27841878 28498854) Discordance in emotional problems in monozygotic twins ( 27043157) Height ( 31562340) Response to fenofibrate (total cholesterol levels) ( 27002377) Systolic blood pressure ( 27618447 27841878 28498854 31217584)
Interacting Genes		18 interacting genes: APOA1 ATXN2 CIC DUSP1 FHL3 GFI1B GPR20 HAX1 IL15 IVNS1ABP MAPK8IP2 NONO SACS SERPINA3 TNS2 TRIML2 UBE2I ZNF593	3 interacting genes: JAM2 POLR1H RPL31
Entrez ID		30834	2843
HPRD ID		09601	03550
Ensembl ID		ENSG00000066379	ENSG00000204882
Uniprot IDs		Q2L6J2 Q9P1U0	Q59GP3 Q99678
PDB IDs		7OB9 7OBA 7OBB 7VBA 7VBB 7VBC 8A43	8HS2 8HS3 8HSC
Enriched GO Terms of Interacting Partners?			Termination Of RNA Polymerase I Transcription Hematopoietic Stem Cell Migration To Bone Marrow Protein Complex Involved In Cell Adhesion Lymphocyte Aggregation Large Ribosomal Subunit RNA Polymerase I Complex DNA-templated Transcription Termination Negative Regulation Of Nervous System Process Leukocyte Aggregation Negative Regulation Of Myelination Somatodendritic Compartment Hematopoietic Stem Cell Migration Leukocyte Tethering Or Rolling Cellular Extravasation Leukocyte Adhesion To Vascular Endothelial Cell Cell-cell Contact Zone DNA-directed RNA Polymerase Activity Maintenance Of Blood-brain Barrier DNA-directed RNA Polymerase Complex Tight Junction Positive Regulation Of Lymphocyte Migration Regulation Of Myelination Cytosolic Large Ribosomal Subunit Leukocyte Cell-cell Adhesion
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