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ANXA2 and TERF1
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
ANXA2
TERF1
Description
annexin A2
telomeric repeat binding factor 1
Image
GO Annotations
Cellular Component
Cornified Envelope
Extracellular Region
Basement Membrane
Extracellular Space
Nucleus
Cytoplasm
Lysosomal Membrane
Endosome
Early Endosome
Lipid Droplet
Cytosol
Plasma Membrane
Adherens Junction
Cell Surface
Vesicle Membrane
Membrane
Basolateral Plasma Membrane
Nuclear Matrix
Midbody
Extracellular Matrix
Late Endosome Membrane
Vesicle
Azurophil Granule Lumen
Myelin Sheath Adaxonal Region
Sarcolemma
Melanosome
Schmidt-Lanterman Incisure
Membrane Raft
Extracellular Exosome
RNA Polymerase II Transcription Regulator Complex
Plasma Membrane Protein Complex
AnxA2-p11 Complex
PCSK9-AnxA2 Complex
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Fibrillar Center
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Cytoplasm
Spindle
Cytoskeleton
Nuclear Body
Shelterin Complex
Molecular Function
Phosphatidylserine Binding
Protease Binding
RNA Binding
Phospholipase Inhibitor Activity
Serine-type Endopeptidase Inhibitor Activity
Calcium Ion Binding
Protein Binding
Calcium-dependent Phospholipid Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Cytoskeletal Protein Binding
Phospholipase A2 Inhibitor Activity
Identical Protein Binding
S100 Protein Binding
Calcium-dependent Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
DNA Binding
Double-stranded Telomeric DNA Binding
Telomerase Activity
Protein Binding
Microtubule Binding
DNA Binding, Bending
Telomeric DNA Binding
Identical Protein Binding
Protein Homodimerization Activity
Ankyrin Repeat Binding
G-rich Strand Telomeric DNA Binding
Biological Process
Angiogenesis
Membrane Raft Assembly
Positive Regulation Of Receptor Recycling
Negative Regulation Of Receptor Internalization
Vesicle Budding From Membrane
Cell Adhesion
Cell-matrix Adhesion
Positive Regulation Of Plasminogen Activation
Response To Activity
Collagen Fibril Organization
Lung Development
Positive Regulation Of Vesicle Fusion
Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process
Osteoclast Development
Fibrinolysis
MRNA Transcription By RNA Polymerase II
Positive Regulation Of Vacuole Organization
Positive Regulation Of Exocytosis
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Neurogenesis
Negative Regulation Of Transport
Positive Regulation Of Multicellular Organismal Process
Cell-cell Adhesion
Epithelial Cell Apoptotic Process
Positive Regulation Of Low-density Lipoprotein Particle Clearance
Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport
Positive Regulation Of Plasma Membrane Repair
Telomere Maintenance
Telomere Maintenance Via Telomerase
Negative Regulation Of DNA Replication
Response To Xenobiotic Stimulus
Telomere Capping
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Meiotic Telomere Clustering
Cell Division
Telomeric D-loop Disassembly
T-circle Formation
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Shelterin Complex Assembly
Negative Regulation Of Establishment Of Protein Localization To Telomere
Negative Regulation Of Establishment Of RNA Localization To Telomere
Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
Negative Regulation Of Telomeric D-loop Disassembly
Pathways
Smooth Muscle Contraction
Neutrophil degranulation
Dissolution of Fibrin Clot
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells
Developmental Lineage of Pancreatic Ductal Cells
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Tenecteplase
Fluocinolone acetonide
Lanoteplase
Artenimol
Diseases
GWAS
Asthma (
31959851
)
Asthma (age of onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Blood protein levels (
30072576
)
Night sleep phenotypes (
27126917
)
Type 2 diabetes (
25102180
)
Age at first sexual intercourse (
34211149
)
Crohn's disease (
22412388
)
Leukocyte telomere length (
31171785
)
Telomere length (
33941849
)
Interacting Genes
51 interacting genes:
ACTA1
APOH
APP
CCDC32
CD99
CDC42
CEACAM1
CTSB
CTSS
DYSF
EIF4ENIF1
FNDC3B
FOXP1
GRB2
HMGA1
LGALS13
LINC00941
LINC01554
LYPLA1
MAP3K4
MYOC
NOD2
OGDH
PHB1
PLA1A
PLA2G4A
PLAT
PLG
POT1
PRKCA
PRKCB
PTEN
RPS2
S100A10
S100A4
S100A6
SLC26A4-AS1
SMN1
SNCA
SNX17
SOS1
SRC
STAT6
TENT2
TERF1
TERT
TNC
TRPV5
WEE2-AS1
YWHAQ
ZBTB4
212 interacting genes:
ACAT2
ACOT7
ACY1
AFAP1L2
AHCY
AK1
AKR1A1
ALDOA
AMPD2
AMPH
ANXA2
ANXA5
ANXA8L1
APEX1
ARHGDIA
ARHGEF3
ARPP21
ASS1
ATM
BCL7B
BIN2
BLM
BRAF
C12orf43
C1orf35
CALD1
CAPNS1
CASP7
CCDC9
CDC6
CDK1
CEP85
CFL1
CKB
CORO1B
CPNE3
CRYBB1
CRYM
DBN1
DBNL
DCX
DDX19B
DDX21
DDX23
DDX24
DDX39A
DLG5
DNAAF11
DNAJB1
DNPH1
DPP3
DPYSL3
EEF1D
EIF4B
ENO2
EPB41L1
EPHX2
EVL
FANCD2
FBP1
FBXO4
FEN1
FES
FKBP8
GAMT
GAPDH
GIT1
GNL3L
GNMT
GSS
H1-1
HCLS1
HDGFL2
HEXIM1
HEXIM2
HGD
HMGN3
HMGN4
HMOX1
HNMT
HOXA3
HSP90AB1
HSPA6
IPO5
JSRP1
KCTD7
KDM1A
KEAP1
KIFBP
KLHDC4
KPNB1
LASP1
LDHA
LDHB
LRSAM1
LYAR
MAP4
MAP7
MAPK12
MAPRE1
MCM2
MDH1
MISP
MSN
MT1X
MVK
NAP1L1
NBN
NEFL
NEK7
NME1
NME2
NOL12
NOL3
NRIP1
NUDCD2
NUDT14
NUMA1
NXNL1
OCM2
OGFR
OGT
PA2G4
PACSIN2
PAFAH1B3
PAGE2
PAICS
PAK4
PCLAF
PCP4
PEPD
PFKP
PFN2
PGD
PGLS
PGM1
PGM2
PINX1
PKM
PNMT
POT1
PPM1G
PRDX1
PRDX6
PRKCB
PTMA
PTPN5
RBMY1A1
RECQL4
RIC8A
RLIM
RNF10
RPAP3
RPL19
RTN3
RTN4
SALL1
SARS1
SBDS
SENP8
SET
SH3BP1
SH3GL2
SH3GL3
SHFL
SIRPD
SKP1
SMAD9
SMARCC2
SNCG
SOAT1
SP100
SRM
SRSF6
STUB1
SULT1C2
SUPT5H
SYK
TALDO1
TBC1D10A
TBCD
TBL1X
TCIRG1
TERT
THG1L
TINAG
TINF2
TKT
TMSB10
TMSB4Y
TNKS
TNKS2
TNPO2
TOMM34
TPI1
TRIM16
TRIP10
TRMT1
TUBB2A
TUBB3
TUBB4B
UBE2M
UTP14A
WARS1
WDR4
WFS1
YWHAG
ZBTB16
ZC3H18
ZFP36L1
ZHX1
ZNF790
Entrez ID
302
7013
HPRD ID
01061
02975
Ensembl ID
ENSG00000182718
ENSG00000147601
Uniprot IDs
A0A024R5Z7
H0YL33
P07355
A0A7I2V5T5
A0A7I2YQE7
P54274
PDB IDs
1W7B
1XJL
2HYU
2HYV
2HYW
4DRW
4FTG
4HRH
5LPU
5LPX
5LQ0
5LQ2
5N7D
5N7F
5N7G
6TWQ
6TWU
6TWX
6TWY
7DTO
7EQ7
7NMI
7P70
7P71
7P72
7P73
7P74
7PC3
7PC4
7PC5
7PC7
7PC8
7PC9
7PCB
7QQL
7QQM
7QQN
7ZVN
7ZVX
8AEL
1BA5
1H6O
1ITY
1IV6
1W0T
3BQO
3L82
5HKP
5WIR
5XUP
8F0A
8F0U
8F1T
8F1U
8F21
8F26
8OX1
8W8G
Enriched GO Terms of Interacting Partners
?
Regulation Of Vesicle-mediated Transport
Extracellular Exosome
Regulation Of Cell Population Proliferation
Enzyme Binding
Regulation Of Locomotion
Negative Regulation Of Wound Healing
Regulation Of Transport
Nuclear Telomere Cap Complex
Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Regulation Of Cell Migration
Positive Regulation Of Metabolic Process
Negative Regulation Of Fibrinolysis
Leukocyte Activation
Regulation Of Cell Motility
Positive Regulation Of Immune System Process
Histone H3T6 Kinase Activity
Positive Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Blood Coagulation
Negative Regulation Of Hemostasis
Regulation Of Cell Junction Assembly
Regulation Of Fibrinolysis
Negative Regulation Of Coagulation
Regulation Of Cell Activation
Positive Regulation Of Organelle Organization
Regulation Of Immune Response
Cell Activation
Regulation Of Cell Adhesion
Regulation Of MAPK Cascade
Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission
Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity
Positive Regulation Of Immune Response
Phosphatidylcholine Lysophospholipase Activity
Extracellular Matrix
Identical Protein Binding
Macrophage Activation
Positive Regulation Of Cell Migration
Regulation Of Endocytosis
Negative Regulation Of Cell-substrate Adhesion
Telomere Maintenance Via Telomerase
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Biosynthetic Process
Regulation Of Immune System Process
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Myeloid Leukocyte Activation
Positive Regulation Of Signal Transduction
Regulation Of Cell-substrate Adhesion
Regulation Of Focal Adhesion Assembly
Trans-synaptic Signaling By BDNF
Protein Kinase C Signaling
Cytosol
Cytoplasm
Extracellular Exosome
Identical Protein Binding
Protein Binding
Nucleobase-containing Compound Metabolic Process
Nicotinamide Nucleotide Metabolic Process
Telomere Maintenance
Chromosome, Telomeric Region
Nucleobase-containing Small Molecule Metabolic Process
Purine-containing Compound Metabolic Process
Telomere Organization
Cadherin Binding
Nucleus
Negative Regulation Of Telomere Maintenance
Purine Nucleotide Metabolic Process
ADP Metabolic Process
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Chromosome Organization
Positive Regulation Of Chromosome Organization
Nucleoside Diphosphate Metabolic Process
Glycolytic Process
Pyruvate Metabolic Process
Positive Regulation Of Cellular Component Organization
Regulation Of Cellular Component Organization
ADP Catabolic Process
Nucleotide Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Regulation Of Telomere Maintenance Via Telomere Lengthening
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Phosphate Metabolic Process
Ficolin-1-rich Granule Lumen
Nucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Metabolic Process
Nucleoside Phosphate Catabolic Process
RNA Binding
Phosphate-containing Compound Metabolic Process
Microtubule Cytoskeleton Organization
Negative Regulation Of DNA Metabolic Process
Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Purine Nucleotide Catabolic Process
Protein Localization To Organelle
Positive Regulation Of Protein-containing Complex Assembly
Cytoskeleton
Positive Regulation Of Organelle Organization
Organelle Organization
Catalytic Activity
Small Molecule Metabolic Process
Organophosphate Catabolic Process
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Tagcloud (Intersection)
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