ABCC2

Gene Name		ATP-binding cassette, sub-family C (CFTR/MRP), member 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Apical Plasma Membrane Intercellular Canaliculus
	Molecular Function	Protein Binding ATP Binding Organic Anion Transmembrane Transporter Activity Protein Domain Specific Binding ATPase Activity, Coupled To Transmembrane Movement Of Substances
	Biological Process	Transport Drug Transmembrane Transport Response To Oxidative Stress Metabolic Process Response To Heat Prostaglandin Transport Cellular Chloride Ion Homeostasis Response To Methotrexate Response To Estrogen Response To Arsenic-containing Substance Transmembrane Transport Thyroid Hormone Transport
Pathways		ABC-family proteins mediated transport
Drugs		Adenosine triphosphate Sulfinpyrazone
Diseases
GWAS
Protein-protein Interactions		10 interactors: AZIN1 CANX MCPH1 NFKB1 PDZD3 PDZK1 RDX SHANK3 SLC9A3R1 UBQLN1
Entrez ID		1244
HPRD ID		03065
Ensembl ID		ENSG00000023839
Uniprot IDs		Q92887
PDB IDs
Enriched GO Terms of Interacting Partners?		Microvillus Assembly Microvillus Organization Protein Localization Renal Phosphate Ion Absorption Negative Regulation Of Interleukin-12 Biosynthetic Process Negative Regulation Of Guanylate Cyclase Activity Negative Regulation Of CGMP Biosynthetic Process Positive Regulation Of Ion Transmembrane Transport Regulation Of Ion Transmembrane Transport Striatal Medium Spiny Neuron Differentiation Negative Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of Polyamine Transmembrane Transport Postsynaptic Density Assembly Guanylate Kinase-associated Protein Clustering Glutathione Transport Regulation Of Cytoskeleton Organization Negative Regulation Of Calcidiol 1-monooxygenase Activity Regulation Of Long Term Synaptic Depression Positive Regulation Of Glutamate Receptor Signaling Pathway Negative Regulation Of Cell Volume Positive Regulation Of Hyaluronan Biosynthetic Process Regulation Of Chromosome Condensation Positive Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Monocarboxylic Acid Transport Regulation Of Ion Transmembrane Transporter Activity Regulation Of Catalytic Activity Cellular Protein Localization Regulation Of Transmembrane Transporter Activity Cellular Localization Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Ion Transport Negative Regulation Of Vitamin D Biosynthetic Process Renal Sodium Ion Transport N-methyl-D-aspartate Receptor Clustering Vocal Learning Positive Regulation Of Synapse Structural Plasticity Negative Regulation Of Cytoskeleton Organization Cellular Phosphate Ion Homeostasis Regulation Of Sodium:proton Antiporter Activity Positive Regulation Of MiRNA Metabolic Process Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Long-term Synaptic Potentiation Negative Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Transport Positive Regulation Of Ion Transport Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering Positive Regulation Of Long-term Neuronal Synaptic Plasticity Phospholipase C-activating Dopamine Receptor Signaling Pathway Cellular Response To Nicotine Negative Regulation Of Catalytic Activity
Tagcloud ?		24c 24t 388g 521c abcc5 bjc bjcancer ces1 clarifying com diarrhoea doi glucuronide hampered irinotecan journal metabolising oatp oatp1b3 personalising pfs pharmacogenetic rs2244613 rs562 slco1b1 sn ugt1a1 www