A1CF and TNPO2

Number of citations of the paper that reports this interaction (PMID 12896982)
16

Data Source:
BioGRID (pull down)
HPRD (in vivo, in vitro)

		A1CF	TNPO2
Gene Name		APOBEC1 complementation factor	transportin 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Endoplasmic Reticulum Apolipoprotein B MRNA Editing Enzyme Complex	Nucleus Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding
	Biological Process	MRNA Processing Gene Expression Cytidine To Uridine Editing MRNA Modification Protein Stabilization	Intracellular Protein Transport
Pathways		mRNA Editing: C to U Conversion mRNA Editing Formation of the Editosome
Drugs
Diseases
GWAS		Urate levels ( 23263486)
Protein-Protein Interactions		9 interactors: APOBEC1 CELF2 FHL3 KHSRP REL SDPR SYNCRIP TNPO2 TRAF1	16 interactors: A1CF APIP C1orf94 CAMK2D CRYAB ELAVL1 EXOC5 KLHL2 NME1 NUP98 NXF1 PIK3CD PNMA5 RAN TCL1B TERF1
Entrez ID		29974	30000
HPRD ID		10627	04301
Ensembl ID		ENSG00000148584	ENSG00000105576
Uniprot IDs		B4E1E3 Q9NQ94	O14787 Q05D48 Q4LE60
PDB IDs		2CPD
Enriched GO Terms of Interacting Partners?		MRNA Processing MRNA Metabolic Process RNA Processing MRNA Stabilization RNA Splicing, Via Transesterification Reactions Regulation Of MRNA Stability Regulation Of RNA Stability RNA Splicing Cytidine To Uridine Editing Negative Regulation Of Methylation-dependent Chromatin Silencing Regulation Of Methylation-dependent Chromatin Silencing CRD-mediated MRNA Stabilization RNA Metabolic Process Base Conversion Or Substitution Editing Negative Regulation Of Chromatin Silencing Gene Expression MRNA Splicing, Via Spliceosome Cytidine Deamination Regulation Of MiRNA Metabolic Process Positive Regulation Of Interleukin-12 Biosynthetic Process Regulation Of Interleukin-12 Biosynthetic Process DNA Demethylation MRNA Modification Positive Regulation Of Gene Expression, Epigenetic Pyrimidine Nucleoside Catabolic Process Lipoprotein Transport Regulation Of Gene Silencing Defense Response See more	RNA Localization Nucleocytoplasmic Transport Nuclear Transport Regulation Of Apoptotic Process Protein Import Into Nucleus, Docking Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Cytidine To Uridine Editing L-methionine Biosynthetic Process From S-adenosylmethionine Intracellular Transport Regulation Of Cell Death Cellular Localization Ribosomal Small Subunit Export From Nucleus Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Natural Killer Cell Chemotaxis B Cell Chemotaxis Mast Cell Differentiation Telomeric Loop Formation Age-dependent Telomere Shortening Protein Oligomerization MRNA Transport Nuclear Export Protein Import Into Nucleus Positive Regulation Of Binding Neutrophil Extravasation Telomere Maintenance Via Telomere Shortening Mast Cell Chemotaxis Regulation Of Generation Of L-type Calcium Current Protein Complex Assembly Nuclear Import DNA Metabolic Process RNA Transport Positive Regulation Of Rac Protein Signal Transduction Respiratory Burst Involved In Defense Response S-adenosylmethionine Cycle Regulation Of Histone Deacetylase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Sodium Ion Transmembrane Transporter Activity MRNA Localization Resulting In Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Viral Process Protein Import Base Conversion Or Substitution Editing Nuclear Pore Complex Assembly Negative Regulation Of Sodium Ion Transmembrane Transport Regulation Of Relaxation Of Cardiac Muscle Establishment Of Localization In Cell Protein Localization To Nucleus Ribosomal Large Subunit Export From Nucleus Regulation Of Cardiac Muscle Cell Action Potential See more
Tagcloud ?		apo apob causality conclusionsincreased crystals editing europeans gout hu immunosorbant introductiongout inverted mark10 mark3 mark6 markmol markori markx methodsnew monosodium msu normouricemia nu polynesian polynesians resultsincreased trended urate vldl
Tagcloud (Difference) ?		apo apob causality conclusionsincreased crystals editing europeans gout hu immunosorbant introductiongout inverted mark10 mark3 mark6 markmol markori markx methodsnew monosodium msu normouricemia nu polynesian polynesians resultsincreased trended urate vldl
Tagcloud (Intersection) ?