PLAGL2 and YPEL5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLAGL2	YPEL5
Description		PLAG1 like zinc finger 2	yippee like 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Ubiquitin Ligase Complex Spindle Pole Extracellular Region Nucleus Cytoplasm Centrosome Cytoskeleton Midbody Mitotic Spindle Pole Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Lipid Metabolic Process Post-embryonic Development Chylomicron Assembly Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Cell Population Proliferation
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Inflammatory bowel disease ( 28067908)	Celiac disease and Rheumatoid arthritis ( 26546613) Low density lipoprotein cholesterol levels ( 33339817) Total cholesterol levels ( 33339817) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		45 interacting genes: ANKRD11 ARID5A BCAS2 CATSPER1 CCDC120 CTNNA3 DAPP1 DHX57 DVL3 FAM161B FAM83A FAM90A1 GADD45G GEM GLYCTK GPATCH2L GYS1 INO80B IRX2 KANK2 MAD2L2 MAPK1 MORN4 NOS1AP OIP5 OLIG3 PAX9 PHC2 PIN1 PLAC8 PRR35 RCHY1 RHOBTB3 RIPPLY1 SAMD11 SEPHS1 SMARCD1 TEKT3 TEKT4 TRAF4 TRIM41 VEZF1 YPEL5 ZNF564 ZNF581	11 interacting genes: CTDSP1 DDIT4L FBXO7 GSC2 MAPKBP1 PFDN5 PLAGL2 PSMA1 SHC3 TRAF5 ZNF655
Entrez ID		5326	51646
HPRD ID		05333	18312
Ensembl ID		ENSG00000126003	ENSG00000119801
Uniprot IDs		Q9UPG8	P62699
PDB IDs			8QBN
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Cell Cycle G1/S Phase Transition Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition RNA Polymerase III Assembly RNA Polymerase I Assembly Negative Regulation Of Cell Cycle Process Glial Cytoplasmic Inclusion Classical Lewy Body Negative Regulation Of Cell Cycle Phase Transition Lewy Body Corona Negative Regulation Of Mitotic Cell Cycle Lewy Neurite Regulation Of Mitotic Cell Cycle Phase Transition RNA Polymerase II Core Complex Assembly Negative Regulation Of Cell Cycle Chylomicron Assembly Lewy Body Core Negative Regulation Of Defense Response To Bacterium Regulation Of Cell Cycle Phase Transition
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