Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
MDFIC and RPS6KA5
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
MDFIC
RPS6KA5
Gene Name
MyoD family inhibitor domain containing
ribosomal protein S6 kinase, 90kDa, polypeptide 5
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Golgi Apparatus
Nucleus
Nucleoplasm
Cytoplasm
Molecular Function
Protein Binding
Transcription Factor Binding
Cyclin Binding
Tat Protein Binding
Magnesium Ion Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Transcription, DNA-templated
Activation Of JUN Kinase Activity
Viral Process
Regulation Of Wnt Signaling Pathway
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Viral Transcription
Negative Regulation Of Cytokine Production
Toll-like Receptor Signaling Pathway
MyD88-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Inflammatory Response
Epidermal Growth Factor Receptor Signaling Pathway
Axon Guidance
Histone Phosphorylation
Positive Regulation Of CREB Transcription Factor Activity
Positive Regulation Of Histone Phosphorylation
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Positive Regulation Of Histone Acetylation
Intracellular Signal Transduction
TRIF-dependent Toll-like Receptor Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Histone H3-S10 Phosphorylation
Histone H3-S28 Phosphorylation
Histone H2A-S1 Phosphorylation
Innate Immune Response
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Neurotrophin TRK Receptor Signaling Pathway
Positive Regulation Of NF-kappaB Transcription Factor Activity
Stress-activated MAPK Cascade
Interleukin-1-mediated Signaling Pathway
Pathways
CREB phosphorylation
Axon guidance
Toll Like Receptor 7/8 (TLR7/8) Cascade
CREB phosphorylation
L1CAM interactions
Recycling pathway of L1
Toll Like Receptor TLR6:TLR2 Cascade
Toll Like Receptor TLR1:TLR2 Cascade
Activated TLR4 signalling
MyD88 cascade initiated on plasma membrane
Toll Like Receptor 5 (TLR5) Cascade
MyD88 dependent cascade initiated on endosome
MyD88:Mal cascade initiated on plasma membrane
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
NCAM signaling for neurite out-growth
Toll Like Receptor 9 (TLR9) Cascade
ERK/MAPK targets
Innate Immune System
Signalling by NGF
MAP kinase activation in TLR cascade
TRIF-mediated TLR3/TLR4 signaling
NGF signalling via TRKA from the plasma membrane
MyD88-independent cascade
Toll Like Receptor 2 (TLR2) Cascade
Toll-Like Receptors Cascades
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 4 (TLR4) Cascade
ERK/MAPK targets
Toll Like Receptor 3 (TLR3) Cascade
MAPK targets/ Nuclear events mediated by MAP kinases
Nuclear Events (kinase and transcription factor activation)
Drugs
Diseases
GWAS
Obesity (
23818313
)
Bone mineral density (
22504420
)
Protein-Protein Interactions
4 interactors:
CCNT1
CDK9
RPS6KA5
SOCS4
59 interactors:
ACTG1
AKT1S1
ALG8
APP
ATF1
ATF2
BAD
CEBPB
CREB1
CREBBP
CRMP1
CSNK2B
DDAH2
DNAJC11
EIF4E
EIF4EBP1
EP300
ERH
ETV1
EZH2
FN1
GPRASP2
HIST1H1B
HIST1H3E
HIST2H2BE
HIST2H3C
HIST2H4A
HIST3H2A
HIST3H2BB
HIST3H3
HIST4H4
HMGN1
HSPB1
HSPB2
IL17RB
ITSN1
MAPK11
MAPK14
MAPT
MBP
MDFIC
NR4A1
PDLIM1
PLA2G4A
RAI1
RELA
RNF19A
ROBO2
RPA1
SMAD6
SMARCB1
STAT1
STAT3
STK11
TH
TXNDC11
UNC119
ZAK
ZNF775
Entrez ID
29969
9252
HPRD ID
17103
06789
Ensembl ID
ENSG00000135272
ENSG00000100784
Uniprot IDs
Q9P1T7
B7Z2Y5
O75582
Q9UG98
PDB IDs
1VZO
3KN5
3KN6
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Viral Transcription
Transcription Elongation From RNA Polymerase II Promoter
Cellular Response To Organic Substance
Regulation Of Cellular Protein Metabolic Process
Regulation Of Viral Transcription
Positive Regulation Of Viral Process
Cellular Response To Growth Factor Stimulus
Cellular Response To Cytokine Stimulus
Response To Growth Factor
DNA-templated Transcription, Elongation
Regulation Of Protein Metabolic Process
Response To Cytokine
Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Histone H2A-S1 Phosphorylation
Replication Fork Arrest
Regulation Of Histone Modification
Enzyme Linked Receptor Protein Signaling Pathway
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Viral Process
Transcription Initiation From RNA Polymerase II Promoter
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Cell Surface Receptor Signaling Pathway
Cellular Protein Modification Process
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Protein Phosphorylation
Response To Transforming Growth Factor Beta
Regulation Of Chromosome Organization
Positive Regulation Of Metabolic Process
DNA-templated Transcription, Initiation
Histone H3-S10 Phosphorylation
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Phosphorylation
Protein Phosphorylation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Histone Phosphorylation
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Gene Expression
Cellular Protein Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Histone H3-S28 Phosphorylation
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Phosphorylation
Regulation Of Nitrogen Compound Metabolic Process
Cytokine-mediated Signaling Pathway
Signal Transduction
Regulation Of Cellular Ketone Metabolic Process
Response To Stress
Positive Regulation Of Cellular Metabolic Process
Response To Stimulus
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Metabolic Process
Defense Response
Enzyme Linked Receptor Protein Signaling Pathway
Response To Abiotic Stimulus
Neurotrophin TRK Receptor Signaling Pathway
Cellular Response To Organic Substance
Cellular Response To Stress
Neurotrophin Signaling Pathway
Cellular Nitrogen Compound Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Regulation Of Metabolic Process
Cell Differentiation
Innate Immune Response
Immune Response
Response To Organic Substance
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
System Development
Regulation Of Cell Differentiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Developmental Process
Nucleobase-containing Compound Metabolic Process
Nitrogen Compound Metabolic Process
Anatomical Structure Development
Response To Hormone
Toll-like Receptor 5 Signaling Pathway
Toll-like Receptor 10 Signaling Pathway
Intracellular Signal Transduction
Cellular Response To Stimulus
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Multicellular Organismal Development
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
Immune System Process
Chromatin Organization
Chromosome Organization
Generation Of Neurons
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Immune Response-regulating Signaling Pathway
Stress-activated MAPK Cascade
MyD88-independent Toll-like Receptor Signaling Pathway
Tagcloud
?
27a
5p
arrays
bioinformatics
cbl
changed
creb
creb1
directive
erk2
escc
esophageal
folds
grb2
mapk1
mapk14
microrna
mir
mirna
mirnas
ngfr
options
prediction
pt1n0
sos1
sprouty
spry2
taqman
verify
Tagcloud (Difference)
?
27a
5p
arrays
bioinformatics
cbl
changed
creb
creb1
directive
erk2
escc
esophageal
folds
grb2
mapk1
mapk14
microrna
mir
mirna
mirnas
ngfr
options
prediction
pt1n0
sos1
sprouty
spry2
taqman
verify
Tagcloud (Intersection)
?