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TIMM22 and PDCD6
Number of citations of the paper that reports this interaction (PMID
11591653
)
37
Data Source:
HPRD
(in vitro)
TIMM22
PDCD6
Gene Name
translocase of inner mitochondrial membrane 22 homolog (yeast)
programmed cell death 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrial Inner Membrane
Integral Component Of Membrane
Nucleus
Cytoplasm
Endosome
Endoplasmic Reticulum
Endoplasmic Reticulum Membrane
Cytoplasmic Vesicle
Nuclear Membrane
Extracellular Vesicular Exosome
Endoplasmic Reticulum Exit Site
Molecular Function
Protein Channel Activity
Calcium-dependent Cysteine-type Endopeptidase Activity
Calcium Ion Binding
Protein Binding
Protein Homodimerization Activity
Protein Anchor
Protein Dimerization Activity
Calcium-dependent Protein Binding
Binding, Bridging
Biological Process
Protein Targeting To Mitochondrion
Cellular Protein Metabolic Process
Protein Import Into Mitochondrial Inner Membrane
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Proteolysis
Intracellular Protein Transport
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Endothelial Cell Migration
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Cellular Response To Heat
Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Angiogenesis
Response To Calcium Ion
Negative Regulation Of Protein Kinase B Signaling
Apoptotic Signaling Pathway
Pathways
Mitochondrial protein import
Drugs
Diseases
GWAS
Protein-Protein Interactions
1 interactors:
PDCD6
18 interactors:
ANXA11
ANXA7
CDKN2A
CPNE1
CPNE2
CPNE4
FAS
FASLG
HEBP2
IGFALS
MAP3K5
MAPK1IP1L
PDCD6IP
PEF1
SH3KBP1
TIMM22
VPS37C
YWHAQ
Entrez ID
29928
10016
HPRD ID
06262
03035
Ensembl ID
ENSG00000249915
Uniprot IDs
Q9Y584
O75340
Q53FC3
PDB IDs
2ZN8
2ZN9
2ZND
2ZNE
2ZRS
2ZRT
3AAJ
3AAK
Enriched GO Terms of Interacting Partners
?
Vascular Endothelial Growth Factor Receptor-2 Signaling Pathway
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Negative Regulation Of Protein Kinase B Signaling
Positive Regulation Of Endothelial Cell Migration
Regulation Of TOR Signaling
Positive Regulation Of Endothelial Cell Proliferation
Cellular Response To Heat
Positive Regulation Of Epithelial Cell Migration
Regulation Of Endothelial Cell Proliferation
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Zymogen Activation
Regulation Of Endothelial Cell Migration
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Response To Heat
Response To Calcium Ion
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Protein Kinase B Signaling
Positive Regulation Of Angiogenesis
Positive Regulation Of Endopeptidase Activity
Regulation Of Epithelial Cell Migration
Positive Regulation Of Peptidase Activity
Positive Regulation Of Epithelial Cell Proliferation
Regulation Of Cellular Response To Growth Factor Stimulus
Response To Temperature Stimulus
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Regulation Of Angiogenesis
Protein Processing
Regulation Of Epithelial Cell Proliferation
Positive Regulation Of Proteolysis
Response To Metal Ion
Positive Regulation Of Cell Migration
Angiogenesis
Positive Regulation Of Cell Motility
Apoptotic Signaling Pathway
Positive Regulation Of Cellular Component Movement
Positive Regulation Of Locomotion
Regulation Of Endopeptidase Activity
Regulation Of Peptidase Activity
Negative Regulation Of Intracellular Signal Transduction
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Protein Processing
Activation Of Cysteine-type Endopeptidase Activity
Zymogen Activation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Programmed Cell Death
Positive Regulation Of Cell Death
Positive Regulation Of Endopeptidase Activity
Cell Death
Death
Positive Regulation Of Peptidase Activity
Programmed Necrotic Cell Death
Necrotic Cell Death
Necroptotic Signaling Pathway
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Response To Inorganic Substance
Membrane Organization
Inflammatory Cell Apoptotic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Proteolysis
Response To Metal Ion
Response To Calcium Ion
Apoptotic Signaling Pathway
T Cell Apoptotic Process
Cell Separation After Cytokinesis
Regulation Of Endopeptidase Activity
Virion Assembly
Regulation Of Peptidase Activity
Necroptotic Process
Regulation Of Cell Death
Negative Regulation Of B Cell Activation
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Proteolysis
Mitochondrial Membrane Organization
Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Positive Regulation Of Neuron Death
Regulation Of ERBB Signaling Pathway
Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Motor Neuron Apoptotic Process
Regulation Of Apoptotic Process
Mitochondrion Organization
Cytokinesis, Completion Of Separation
Senescence-associated Heterochromatin Focus Assembly
Endosomal Lumen Acidification
Tagcloud
?
adp
bax
bcl
caspase
cdk4
cisplatin
cleavages
define
irradiation
luciferase
ovarian
overexpressing
p16
p21
p27
parp
pdk1
poly
pro
programmed
regulators
ribose
skov
suppressing
tnfalpha
tumorigenesis
uv
xl
Tagcloud (Difference)
?
adp
bax
bcl
caspase
cdk4
cisplatin
cleavages
define
irradiation
luciferase
ovarian
overexpressing
p16
p21
p27
parp
pdk1
poly
pro
programmed
regulators
ribose
skov
suppressing
tnfalpha
tumorigenesis
uv
xl
Tagcloud (Intersection)
?