HILPDA and BDKRB1

Number of citations: 90 (PubMedID 28298427)
Data Source: BioGRID (two hybrid)

		HILPDA	BDKRB1
Name		hypoxia inducible lipid droplet associated	bradykinin receptor B1
Structure		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Lipid Droplet Cytosol Cell Surface Membrane Secretory Granule	Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Signaling Receptor Binding Protein Binding	G Protein-coupled Receptor Activity Bradykinin Receptor Activity Protein Binding Peptide Binding
	Biological Process	Positive Regulation Of Cytokine Production Positive Regulation Of Cell Population Proliferation Positive Regulation Of Lipid Storage Autocrine Signaling Cellular Response To Hypoxia	Positive Regulation Of Leukocyte Migration Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Mechanical Stimulus Cell Migration Negative Regulation Of Cell Growth Response To Lipopolysaccharide Negative Regulation Of Blood Pressure Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Pathways		Lipid particle organization	Peptide ligand-binding receptors G alpha (q) signalling events G alpha (i) signalling events
Drugs		None	Ramipril Captopril Zinc Enalaprilat Zinc acetate Zinc chloride Zinc sulfate, unspecified form
GWAS		No GWAS studies recorded	Metabolite levels ( 23823483 )
Novel Interactors		2 novel interactors: GCC1 RBM28	2 novel interactors: DNAJB13 EVL
Interacting Genes		2 interacting genes: BDKRB1 GET3	32 interacting genes: CERS1 DNAJB1 GABBR1 GNAQ GRIN1 HHATL HILPDA HTT INSIG1 LAPTM4B LRRC4C LTAP1 MBOAT7 MDC1 NAGPA NAP1L4 NDFIP1 NF2 OAZ2 RAE1 RETREG1 RTN4 SLC25A28 SLC39A14 SLC44A2 SLC6A8 TMEM42 TMX2 TRAM1L1 TRAT1 UQCRC1 ZNF22
Entrez ID		29923	623
HPRD ID		17105	02639
Ensembl ID		ENSG00000135245	ENSG00000100739
Uniprot IDs		Q9Y5L2	P46663
PDB IDs		Not available	7EIB
GO Terms Enriched among Interactors		GET Complex Bradykinin Receptor Activity	Endoplasmic Reticulum Membrane Membrane Ferrous Iron Transmembrane Transporter Activity Brain Development Iron Ion Transmembrane Transporter Activity Negative Regulation Of Transport Profilin Binding