CNOT7 and BTG3

Number of citations of the paper that reports this interaction (PMID 11429045)
13

Data Source:
HPRD (in vitro)

		CNOT7	BTG3
Gene Name		CCR4-NOT transcription complex, subunit 7	BTG family, member 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Nucleus Cytosol Membrane CCR4-NOT Complex	Cytoplasm
	Molecular Function	3'-5'-exoribonuclease Activity Sequence-specific DNA Binding Transcription Factor Activity RNA Binding Exoribonuclease Activity Poly(A)-specific Ribonuclease Activity Signal Transducer Activity Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Carbohydrate Metabolic Process Transcription, DNA-templated Regulation Of Translation Signal Transduction Positive Regulation Of Cell Proliferation Negative Regulation Of Cell Proliferation Gene Expression Negative Regulation Of Gene Expression Gene Silencing By RNA Cytoplasmic MRNA Processing Body Assembly Gene Silencing By MiRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of MRNA Catabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay	Negative Regulation Of Cell Proliferation Negative Regulation Of Mitotic Cell Cycle
Pathways		Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: APP BTG1 BTG2 BTG3 CDK1 CDK2 CDK4 CDK6 CNOT6 FOXC2 HOXD4 IKBKG PABPC1 TNRC6A TOB1 TOB2	4 interactors: ATXN1 BANP CACNA1A CNOT7
Entrez ID		29883	10950
HPRD ID		05370	10415
Ensembl ID		ENSG00000198791	ENSG00000154640
Uniprot IDs		Q9UIV1	Q14201 Q6IAU3
PDB IDs		2D5R 4GMJ
Enriched GO Terms of Interacting Partners?		Regulation Of Translation Regulation Of Gene Expression Regulation Of Cell Proliferation Positive Regulation Of Gene Expression Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of MRNA 3'-end Processing Regulation Of MRNA 3'-end Processing Regulation Of Protein Metabolic Process Positive Regulation Of MRNA Catabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Notch Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cell Proliferation G1/S Transition Of Mitotic Cell Cycle Regulation Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Gene Silencing By RNA Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Cellular Process Regulation Of Cell Cycle MRNA 3'-end Processing Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Negative Regulation Of Translation Regulation Of MRNA Processing Positive Regulation Of Cell Cycle Regulation Of Cell Differentiation Gene Silencing Regulation Of Nitrogen Compound Metabolic Process RNA 3'-end Processing Positive Regulation Of Mitotic Cell Cycle Dentate Gyrus Development Negative Regulation Of Cell Differentiation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Gene Expression Positive Regulation Of Cell Proliferation Cell Division MRNA Polyadenylation Regulation Of Apoptotic Process Gene Silencing By MiRNA RNA Polyadenylation	Adult Locomotory Behavior Membrane Depolarization Cerebellar Molecular Layer Development Adult Behavior Vestibular Nucleus Development Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Locomotory Behavior Gamma-aminobutyric Acid Secretion Regulation Of Acetylcholine Secretion, Neurotransmission Regulation Of Membrane Potential Rhythmic Synaptic Transmission Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cytoplasmic MRNA Processing Body Assembly Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Hormone Biosynthetic Process Pons Development Single-organism Behavior Cerebellar Purkinje Cell Differentiation Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Cerebellar Purkinje Cell Layer Morphogenesis Nitrogen Compound Metabolic Process RNA Processing Transcription, DNA-templated Positive Regulation Of MRNA Catabolic Process Synaptic Transmission Reflex Behavior Behavioral Response To Pain RNA Biosynthetic Process Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cellular Localization Nuclear-transcribed MRNA Poly(A) Tail Shortening Neuromuscular Synaptic Transmission Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Regulation Of Hormone Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Cerebellar Cortex Formation Neurotransmitter Metabolic Process RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Gamma-aminobutyric Acid Signaling Pathway Cell Differentiation In Hindbrain Calcium Ion Import
Tagcloud ?		actr1a backgrounds bbs2 bovines c2orf29 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131	3beta ablation acts akt avenue binds catenin connects consequently deregulated diminished downregulated e2f1 functionally glycogen inhibits insights mechanistic mesenchymal phosphorylates recapitulates suppresses synthase therapeutics uncharacterized unreported unveils upregulation xenografts
Tagcloud (Difference) ?		actr1a backgrounds bbs2 bovines c2orf29 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131	3beta ablation acts akt avenue binds catenin connects consequently deregulated diminished downregulated e2f1 functionally glycogen inhibits insights mechanistic mesenchymal phosphorylates recapitulates suppresses synthase therapeutics uncharacterized unreported unveils upregulation xenografts
Tagcloud (Intersection) ?