TCF3 and RALGAPA1

Number of citations of the paper that reports this interaction (PMID 12200424)
3

Data Source:
HPRD (in vivo)

		TCF3	RALGAPA1
Gene Name		transcription factor 3	Ral GTPase activating protein, alpha subunit 1 (catalytic)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Nucleosome Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Protein Complex RNA Polymerase II Transcription Factor Complex	Nucleus Cytoplasm
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Mitogen-activated Protein Kinase Kinase Kinase Binding Enhancer Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity Repressing Transcription Factor Binding Vitamin D Response Element Binding E-box Binding	Ral GTPase Activator Activity Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Natural Killer Cell Differentiation B Cell Lineage Commitment Transcription, DNA-templated Regulation Of Transcription, DNA-templated B Cell Differentiation Positive Regulation Of B Cell Proliferation Response To Lipopolysaccharide T Cell Differentiation In Thymus Immunoglobulin V(D)J Recombination Response To Drug Muscle Cell Differentiation Histone H3 Acetylation Histone H4 Acetylation Positive Regulation Of Neuron Differentiation Positive Regulation Of Cell Cycle Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Cell Development Peyer's Patch Development Protein Stabilization Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Muscle Cell Differentiation Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Transcription, DNA-templated Activation Of Ral GTPase Activity
Pathways		CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		62 interactors: AEBP1 ASCL3 BHLHA15 CALM1 CALM3 CBFA2T3 CREBBP CTNNB1 DAXX ELK3 EP300 FERD3L HAND1 HAND2 HOXA1 ID1 ID2 ID3 KAT2A KAT2B LMX1A LMX1B LYL1 MAPK1 MAPK3 MAPKAPK2 MAPKAPK3 MAX MDFI MEN1 MSC MYF5 MYF6 MYOD1 MYOG NEDD9 NHLH1 PDX1 PRKACA PSMD4 PSMD9 RALGAPA1 RPL37 RUFY1 RUNX1T1 SKP2 SRF SUPT3H TADA2A TAL1 TAL2 TCAF1 TCF12 TCF21 TCF4 TFPT TLE1 TRRAP TWIST1 UBE2I USF1 VDR	1 interactors: TCF3
Entrez ID		6929	253959
HPRD ID		00918	12324
Ensembl ID		ENSG00000071564	ENSG00000174373
Uniprot IDs		P15923 Q2TB39	Q6GYQ0
PDB IDs		1HLH 2YPA 2YPB 3U5V
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Organ Development Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process System Development Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Anatomical Structure Development Multicellular Organismal Development Developmental Process Embryo Development Tissue Development Organ Morphogenesis Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Binding Embryonic Morphogenesis Cell Differentiation Anatomical Structure Morphogenesis Embryonic Organ Development	Positive Regulation Of Transcription From RNA Polymerase II Promoter During Mitosis Axial Mesoderm Morphogenesis Immunoglobulin V(D)J Recombination Axial Mesoderm Development B Cell Lineage Commitment Peyer's Patch Development Natural Killer Cell Differentiation Anterior/posterior Axis Specification, Embryo Regulation Of Stem Cell Maintenance V(D)J Recombination Somatic Recombination Of Immunoglobulin Gene Segments Somatic Diversification Of Immunoglobulins Positive Regulation Of B Cell Proliferation Histone H3 Acetylation Histone H4 Acetylation Embryonic Axis Specification Regulation Of B Cell Proliferation Natural Killer Cell Activation Immunoglobulin Production T Cell Differentiation In Thymus Somatic Stem Cell Maintenance Anterior/posterior Axis Specification Positive Regulation Of B Cell Activation Positive Regulation Of Muscle Cell Differentiation Embryonic Pattern Specification Protein Stabilization Mesoderm Morphogenesis Canonical Wnt Signaling Pathway B Cell Differentiation Histone Acetylation Positive Regulation Of Lymphocyte Proliferation Axis Specification Positive Regulation Of Mononuclear Cell Proliferation Segmentation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Protein Stability Regulation Of Cell Cycle G1/S Phase Transition Mesoderm Development Stem Cell Maintenance T Cell Differentiation Regulation Of Muscle Cell Differentiation B Cell Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Mitotic Cell Cycle Phase Transition Skin Development Regulation Of Cell Cycle Phase Transition
Tagcloud ?		advantageous characterize chimpanzee crebbp eleven ep300 evolution fgf2 germ gorilla hdac3 macaque macaques mapped microarrays orangutan organs partners primate prkd3 profiled profiling proteomics regard runx1 runx2 satb2 testis yap1
Tagcloud (Difference) ?		advantageous characterize chimpanzee crebbp eleven ep300 evolution fgf2 germ gorilla hdac3 macaque macaques mapped microarrays orangutan organs partners primate prkd3 profiled profiling proteomics regard runx1 runx2 satb2 testis yap1
Tagcloud (Intersection) ?