SEMA3B and RBPMS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SEMA3B	RBPMS2
Description		semaphorin 3B	RNA binding protein, mRNA processing factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Plasma Membrane Extracellular Matrix	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule
	Molecular Function	Protein Binding Semaphorin Receptor Binding Neuropilin Binding Chemorepellent Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Neural Crest Cell Migration Cell-cell Signaling Axon Guidance Positive Regulation Of Cell Migration Negative Chemotaxis Chemorepulsion Of Axon Semaphorin-plexin Signaling Pathway	Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of BMP Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS		Obese vs. thin ( 30677029) Sleep duration (short sleep) ( 30846698) Waist circumference adjusted for body mass index ( 34021172)	Coronary artery disease ( 29212778) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Platelet count ( 32888494) PR interval ( 32439900)
Interacting Genes		23 interacting genes: BOLL CARD10 CREBBP CYSRT1 HSF2BP KPRP KRTAP1-1 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP19-5 KRTAP5-9 MDFI NAA10 NBPF19 NOTCH2NLA NRP1 NRP2 PAK6 PICK1 RBPMS2 SEMA3A TRIP13	68 interacting genes: ACTMAP AOC1 ARID5A BHLHE40 BOLL C10orf55 CAMK2A CBX2 CELF4 DND1 ESRP1 FAM168A FOXD4L1 FOXD4L3 FOXH1 FUBP3 HNRNPC HNRNPK HNRNPU IFIT2 KLF1 KLHDC7B KRTAP11-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MAGED1 MKRN3 MSX2 MYPOP PATZ1 PCBP1 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PTBP2 RALY RBFOX1 RBFOX2 RBM3 RBM41 RBM42 RBM46 RBPMS RHOXF2 SEMA3B SNRPA SPMIP9 STRBP TENT5B TIAL1 UFSP1 UNC119 USP54 VHL VPS37C ZBTB32 ZC3H10 ZMAT5 ZNF34 ZNF385C
Entrez ID		7869	348093
HPRD ID		03179	18601
Ensembl ID		ENSG00000012171	ENSG00000166831
Uniprot IDs		A0A0C4DGV8 B4DEK9 Q13214 Q6PI51	Q6ZRY4
PDB IDs			2M9K
Enriched GO Terms of Interacting Partners?		Sympathetic Neuron Projection Guidance Trigeminal Nerve Structural Organization Neural Crest Cell Migration Involved In Autonomic Nervous System Development Sympathetic Neuron Projection Extension Intermediate Filament Branchiomotor Neuron Axon Guidance Facial Nerve Structural Organization Sympathetic Ganglion Development Axon Extension Involved In Axon Guidance Ganglion Development Vestibulocochlear Nerve Structural Organization Anatomical Structure Arrangement Dorsal Root Ganglion Morphogenesis Sensory Neuron Axon Guidance Facioacoustic Ganglion Development Neuron Projection Arborization Ventral Trunk Neural Crest Cell Migration Neuron Projection Extension Basal Dendrite Arborization Basal Dendrite Morphogenesis Motor Neuron Axon Guidance Trigeminal Ganglion Development Cranial Ganglion Development Trunk Neural Crest Cell Migration Developmental Cell Growth Semaphorin-plexin Signaling Pathway Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Developmental Growth Involved In Morphogenesis Axon Extension Vascular Endothelial Growth Factor Receptor Activity Female Meiosis I Hypothalamus Cell Migration Neural Crest Cell Migration Mesenchymal Cell Migration Axonogenesis Involved In Innervation N-terminal Protein Amino Acid Acetylation Dendrite Arborization Semaphorin Receptor Activity Semaphorin Receptor Complex Regulation Of Axon Extension Involved In Axon Guidance Sympathetic Nervous System Development Keratin Filament Identical Protein Binding Acetyltransferase Activity Tissue Development Vascular Endothelial Growth Factor Signaling Pathway Female Meiotic Nuclear Division Developmental Process Male Meiosis I Outflow Tract Septum Morphogenesis	Nucleic Acid Binding Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Metabolic Process RNA Binding Regulation Of RNA Splicing MRNA Binding RNA Splicing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Negative Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Stabilization MRNA Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Primary Metabolic Process Negative Regulation Of RNA Catabolic Process Intermediate Filament Negative Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Protein Binding Ribonucleoprotein Complex Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Pre-mRNA Binding Negative Regulation Of Macromolecule Metabolic Process Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression DNA Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Metabolic Process RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II
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