SEMA3B and PAK6

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SEMA3B	PAK6
Gene Name		sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	p21 protein (Cdc42/Rac)-activated kinase 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm
	Molecular Function	Receptor Activity	Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Cell-cell Signaling Axon Guidance	Mitotic Cell Cycle Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Cytoskeleton Organization Signal Transduction By Phosphorylation Intracellular Signal Transduction
Pathways			Axon guidance Activation of Rac Signaling by Robo receptor
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		4 interactors: NRP1 NRP2 PAK6 SEMA3A	13 interactors: AKT1 APP AR CDC42 CDK1 ESR1 MAPK14 MDM2 NEK6 RHOJ SEMA3B SNX2 TPD52L1
Entrez ID		7869	56924
HPRD ID		03179	06426
Ensembl ID			ENSG00000137843
Uniprot IDs		Q13214	B3KYB0 G5E9R2 Q9NQU5
PDB IDs			2C30 2ODB 4KS7 4KS8
Enriched GO Terms of Interacting Partners?		Facioacoustic Ganglion Development Gonadotrophin-releasing Hormone Neuronal Migration To The Hypothalamus Sympathetic Neuron Projection Extension Sympathetic Neuron Projection Guidance Ventral Trunk Neural Crest Cell Migration Hypothalamus Cell Migration Neural Crest Cell Migration Involved In Autonomic Nervous System Development Trigeminal Ganglion Development Semaphorin-plexin Signaling Pathway Involved In Neuron Projection Guidance Hypothalamus Cell Differentiation Axon Extension Involved In Axon Guidance Sympathetic Ganglion Development Facial Nerve Structural Organization Facial Nerve Morphogenesis Cerebral Cortex Tangential Migration Ganglion Development Parasympathetic Nervous System Development Anatomical Structure Arrangement Sympathetic Nervous System Development Hypothalamus Development Semaphorin-plexin Signaling Pathway Forebrain Neuron Development Substrate-dependent Cell Migration Axon Extension Autonomic Nervous System Development Vestibulocochlear Nerve Structural Organization Ganglion Morphogenesis Neural Crest Cell Migration Cranial Nerve Development Sensory Neuron Axon Guidance Forebrain Neuron Differentiation Neuron Projection Extension Neural Crest Cell Development Forebrain Generation Of Neurons Neural Crest Cell Differentiation Developmental Cell Growth Axonogenesis Involved In Innervation Trigeminal Nerve Structural Organization Semaphorin-plexin Signaling Pathway Involved In Axon Guidance Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Embryonic Pattern Specification Cerebral Cortex Cell Migration Diencephalon Development Nerve Development Branchiomotor Neuron Axon Guidance Limbic System Development Telencephalon Cell Migration Forebrain Cell Migration Central Nervous System Neuron Development Mesenchymal Cell Development	Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Intracellular Signal Transduction Positive Regulation Of Intracellular Transport Vascular Endothelial Growth Factor Receptor Signaling Pathway Apoptotic Process Positive Regulation Of Cell Cycle Positive Regulation Of Gene Expression Programmed Cell Death Peptidyl-serine Phosphorylation Cell Death Death Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Establishment Of Protein Localization Positive Regulation Of Cellular Metabolic Process DNA Damage Checkpoint Regulation Of Protein Kinase Activity Regulation Of Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Intracellular Protein Transport Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction ERBB Signaling Pathway Regulation Of Mitotic Cell Cycle Regulation Of Protein Localization Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Cellular Protein Metabolic Process Innate Immune Response Regulation Of Intracellular Transport Positive Regulation Of Cell Proliferation Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Phosphorylation Immune Response-regulating Signaling Pathway Regulation Of Cell Cycle Process Regulation Of Apoptotic Process Positive Regulation Of Kinase Activity Growth Neurotrophin TRK Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Macromolecule Biosynthetic Process Neurotrophin Signaling Pathway Positive Regulation Of Catalytic Activity Cell Cycle Checkpoint Regulation Of Cell Death Signaling Positive Regulation Of Cellular Biosynthetic Process
Tagcloud ?		ags aza bgc bisulfite bsp clearly cpg demethylating deoxycytidine differentially downregulation epigenetically exploring gastric gc hypermethylation methylated methylation mgc negatively paired possess semaphorin semaphorins sgc staging status usage	19a 19b1 5p apaf1 beclin1 daci exerts favor hep3b hepg2 hsa impedance inc interfere lbh589 mentioned mimicking mir30a mirna mirnas oligonucleotides oncomirs panobinostat periodicals proving qpcr restoring transfecting wiley
Tagcloud (Difference) ?		ags aza bgc bisulfite bsp clearly cpg demethylating deoxycytidine differentially downregulation epigenetically exploring gastric gc hypermethylation methylated methylation mgc negatively paired possess semaphorin semaphorins sgc staging status usage	19a 19b1 5p apaf1 beclin1 daci exerts favor hep3b hepg2 hsa impedance inc interfere lbh589 mentioned mimicking mir30a mirna mirnas oligonucleotides oncomirs panobinostat periodicals proving qpcr restoring transfecting wiley
Tagcloud (Intersection) ?