AP4S1 and TEAD3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		AP4S1	TEAD3
Gene Name		adaptor-related protein complex 4, sigma 1 subunit	TEA domain family member 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Coated Pit	Nucleoplasm Transcription Factor Complex
	Molecular Function	Transporter Activity Protein Transporter Activity	RNA Polymerase II Transcription Factor Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding
	Biological Process	Protein Transport	Regulation Of Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Female Pregnancy Gene Expression Hippo Signaling Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Stem Cell Maintenance
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Generic Transcription Pathway Metabolism of lipids and lipoproteins YAP1- and WWTR1 (TAZ)-stimulated gene expression Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		6 interactors: AFP AP4E1 APP GRB2 GTF2I TEAD3	13 interactors: AP4S1 CTBP2 E2F1 E2F3 KIFC2 MYH7 PHB2 PIDD1 SUMO2 VGLL1 VGLL2 WWTR1 YAP1
Entrez ID		11154	7005
HPRD ID		06257	04411
Ensembl ID		ENSG00000100478	ENSG00000007866
Uniprot IDs		Q9Y587	Q99594
PDB IDs
Enriched GO Terms of Interacting Partners?		Reproductive Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Transition Between Slow And Fast Fiber Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Transcription Initiation From RNA Polymerase II Promoter Platelet Activation Collateral Sprouting Axon Midline Choice Point Recognition DNA-templated Transcription, Initiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Steroid Metabolic Process Positive Regulation Of Stem Cell Maintenance Regulation Of Skeletal Muscle Adaptation Cellular Calcium Ion Homeostasis Negative Regulation Of Cytosolic Calcium Ion Concentration Neuron Remodeling Calcium Ion Homeostasis Branching Involved In Labyrinthine Layer Morphogenesis Signal Transduction Ovulation From Ovarian Follicle Signaling Axon Guidance Vesicle-mediated Transport Cell Communication Cellular Metal Ion Homeostasis Blood Coagulation Cellular Copper Ion Homeostasis Hemostasis Cellular Cation Homeostasis Response To Radiation Cellular Ion Homeostasis Progesterone Metabolic Process Ovulation Metal Ion Homeostasis Labyrinthine Layer Morphogenesis Copper Ion Homeostasis Suckling Behavior	Transcription, DNA-templated Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Nephron Tubule Epithelial Cell Differentiation Regulation Of Epithelial Cell Differentiation Involved In Kidney Development Regulation Of Cell Proliferation Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Hippo Signaling Positive Regulation Of Metabolic Process Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Stem Cell Differentiation Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Proliferation Nucleobase-containing Compound Metabolic Process Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Tissue Development Organ Morphogenesis Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process Signal Transduction By P53 Class Mediator Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Lens Fiber Cell Apoptotic Process Negative Regulation Of Transcription, DNA-templated Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Epithelial Cell Differentiation Notch Signaling Pathway Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
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