SLC25A6 and TRIP6

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SLC25A6	TRIP6
Gene Name		solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	thyroid hormone receptor interactor 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Inner Membrane Presequence Translocase Complex Integral Component Of Membrane	Nucleus Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Interleukin-1 Receptor Complex
	Molecular Function	ATP:ADP Antiporter Activity Protein Binding	Interleukin-1 Receptor Binding Protein Binding Zinc Ion Binding Kinase Binding Poly(A) RNA Binding Thyroid Hormone Receptor Binding
	Biological Process	Energy Reserve Metabolic Process Protein Targeting To Mitochondrion Apoptotic Process ADP Transport ATP Transport Viral Process Modulation By Virus Of Host Morphology Or Physiology Viral Life Cycle Cellular Protein Metabolic Process Small Molecule Metabolic Process Active Induction Of Host Immune Response By Virus Regulation Of Insulin Secretion Transmembrane Transport	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Release Of Cytoplasmic Sequestered NF-kappaB Positive Regulation Of Cell Migration Focal Adhesion Assembly
Pathways		Integration of energy metabolism Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization HIV Infection Regulation of insulin secretion Host Interactions of HIV factors Mitochondrial protein import Host Interactions with Influenza Factors Influenza Infection Influenza Virus Induced Apoptosis Interactions of Vpr with host cellular proteins
Drugs		Clodronate
Diseases
GWAS			Plasminogen activator inhibitor type 1 levels (PAI-1) ( 22990020)
Protein-Protein Interactions		18 interactors: AP2B1 CHGB FGFR3 KARS KRT31 KRTAP4-12 LZTS2 MID2 MTUS2 NOTCH2NL PLSCR1 PRSS23 STRN4 TEKT4 TRAF1 TRIM23 TRIP6 VIM	105 interactors: ABI2 ADAMTSL4 AQP1 ARNT2 ATN1 ATP5O ATXN1 BCAR1 BYSL CATSPER1 CBLC CCL5 CEP57L1 CNTF CREB5 CTAG2 DHX37 DMRT3 DTX2 EXOC3-AS1 FAM124B FAM154A FAM46C FASLG FHL3 FRS3 GDPD5 GFI1B GNAI2 GSE1 HLA-DPB1 HOXA1 HOXA9 HOXB9 HYKK ILF3 INCA1 KIAA1683 KIF1A KIR2DL4 KLK15 KRTAP26-1 LMO2 LOC149950 LPAR2 MAPKBP1 MEMO1 METTL17 MSRB3 MVP NCK2 NEDD9 NEU4 NUP210 ODF1 OIP5 OTUB2 PDGFRB PDLIM4 PIN1 POM121 POM121L4P PPP1R16A PRKAA1 PRKAA2 PTK2 PTPN13 PXN RAD23A RERE RFX3 RHOA RHOQ RNF213 RNF214 SCRIB SIK3 SLC15A3 SLC25A6 SMAD1 SON SRC STAC STK16 SVIL SYNGAP1 TAB1 TCAF1 TEKT4 THRB TLR2 TMSB4X TPM3 TPM4 TRAF3IP2 TRAPPC2L TRIM29 TTLL10 TXN2 TXNDC5 VCL WT1-AS XRCC6BP1 YPEL3 ZBP1
Entrez ID		293	7205
HPRD ID		02461	04242
Ensembl ID			ENSG00000087077
Uniprot IDs		P12236 Q6I9V5	F2ZC06 Q15654
PDB IDs			1X61 2DLO
Enriched GO Terms of Interacting Partners?		Lens Fiber Cell Development Lens Fiber Cell Differentiation Viral Process Lysyl-tRNA Aminoacylation Fibroblast Growth Factor Receptor Apoptotic Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Viral Process Diadenosine Tetraphosphate Biosynthetic Process Regulation Of Signaling Lens Development In Camera-type Eye Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Glial Cell Development Apoptotic Process Positive Regulation Of NF-kappaB Transcription Factor Activity	Signal Complex Assembly Cellular Response To Organic Substance Positive Regulation Of Cellular Metabolic Process Response To Organic Substance Regulation Of Signaling Actin Filament-based Process Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Positive Regulation Of Intracellular Signal Transduction Response To Growth Factor Cytoskeleton Organization Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction ERBB Signaling Pathway Cell Communication Cellular Process Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Phosphorylation Multicellular Organismal Development Regulation Of Apoptotic Process Response To Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Cellular Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Response To Transforming Growth Factor Beta Regulation Of Protein Phosphorylation Cellular Response To Stimulus Platelet Activation Response To Hormone Response To Stress Cellular Response To Growth Factor Stimulus Response To Wounding Regulation Of Protein Metabolic Process Regulation Of Cell Death Actin Cytoskeleton Organization Wound Healing Signaling Transforming Growth Factor Beta Receptor Signaling Pathway Organ Development Regulation Of Cell Motility Cell Motility Regulation Of Phosphorus Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Process
Tagcloud ?		aberrant blastocyst bovine cattle clones cows embryo embryos freemartin gestation hatched hprt inner lost mecp2 pregnancies recipient reconstructed rps4x rq scnt somatic telomerase transcript transfer twin xiap xist zfx	adaptors ap competition dimerization discrete domains enables enhances example exerts focal glucocorticoid gr interacts intriguing isoform lim med1 mediating mediator negatively orchestrating promoters recruitment tethering thought thrap3 transrepression
Tagcloud (Difference) ?		aberrant blastocyst bovine cattle clones cows embryo embryos freemartin gestation hatched hprt inner lost mecp2 pregnancies recipient reconstructed rps4x rq scnt somatic telomerase transcript transfer twin xiap xist zfx	adaptors ap competition dimerization discrete domains enables enhances example exerts focal glucocorticoid gr interacts intriguing isoform lim med1 mediating mediator negatively orchestrating promoters recruitment tethering thought thrap3 transrepression
Tagcloud (Intersection) ?