SLC25A6 and STRN4

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		SLC25A6	STRN4
Name		solute carrier family 25 member 6	striatin 4
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane TIM23 Mitochondrial Import Inner Membrane Translocase Complex Membrane	Cytoplasm Dendrite Protein-containing Complex Neuronal Cell Body Dendritic Spine FAR/SIN/STRIPAK Complex Postsynapse Glutamatergic Synapse GABA-ergic Synapse
	Molecular Function	ATP:ADP Antiporter Activity Protein Binding Antiporter Activity	Protein Binding Calmodulin Binding Protein Domain Specific Binding Protein-macromolecule Adaptor Activity Protein-containing Complex Binding Protein Phosphatase 2A Binding Armadillo Repeat Domain Binding
	Biological Process	Apoptotic Process Transmembrane Transport Mitochondrial ADP Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitochondrial ATP Transmembrane Transport	Negative Regulation Of Hippo Signaling Regulation Of Modification Of Postsynaptic Structure
Pathways		Mitochondrial protein import Mitochondrial protein import Influenza Virus Induced Apoptosis Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Mitochondrial protein degradation	None
Drugs		Clodronic acid Etidronic acid	None
GWAS		No GWAS studies recorded	Aspartate aminotransferase levels ( 33547301 ) Chronic lymphocytic leukemia ( 18758461 28165464 ) Primary sclerosing cholangitis ( 23603763 )
Interacting Genes		20 interacting genes: AP2B1 CHEK2 CHGB DUX4 FGFR3 KARS1 KRT31 KRTAP4-12 LZTS2 MID2 MTUS2 NOTCH2NLA PLSCR1 PRSS23 STRN4 TEKT4 TRAF1 TRIM23 TRIP6 VIM	28 interacting genes: AK5 ASNS CALM1 CAV1 CLDN12 CRK DDX39B DFFA ECSIT GDF9 JUN KLHDC2 MAP4K1 MAP4K2 MAP4K3 MAP4K4 MIF MSANTD2 MTG1 NBEA PBDC1 PI4KA PLPPR3 PPBP SLC25A6 TNIK WIPI2 WNT7A
Entrez ID		293	29888
HPRD ID		02461	18125
Ensembl ID		ENSG00000169100	ENSG00000090372
Uniprot IDs		P12236 Q6I9V5	F5GYK2 Q59GV6 Q9NRL3
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		None	MAP Kinase Kinase Kinase Kinase Activity MAPK Cascade Regulation Of MAPK Cascade JNK Cascade Regulation Of JNK Cascade Intracellular Signaling Cassette Positive Regulation Of MAPK Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Apoptotic Process Positive Regulation Of Intracellular Signal Transduction Kinase Activity Intracellular Signal Transduction Negative Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Response To Transforming Growth Factor Beta Stimulus Nucleotide Binding ATP Binding Response To Transforming Growth Factor Beta Protein Serine Kinase Activity Protein Phosphorylation Signal Transduction Regulation Of Cell Communication By Electrical Coupling Positive Regulation Of Cell Communication Positive Regulation Of Signaling Phosphorylation Cytokine Activity Regulation Of Fibroblast Proliferation Protein Serine/threonine Kinase Activity Positive Regulation Of Cell Junction Assembly Regulation Of Intracellular Signal Transduction Regulation Of Cardiac Muscle Cell Action Potential