SLC25A5 and RNF26

Number of citations of the paper that reports this interaction (PubMedID 37519262)
92

Data Source:
BioGRID (pull down)

		SLC25A5	RNF26
Description		solute carrier family 25 member 5	ring finger protein 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Membrane Mitochondrial Nucleoid MMXD Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane
	Molecular Function	Adenine Nucleotide Transmembrane Transporter Activity RNA Binding ATP:ADP Antiporter Activity Protein Binding Proton Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Antiporter Activity Oxidative Phosphorylation Uncoupler Activity Ubiquitin Protein Ligase Binding	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Chromosome Segregation Positive Regulation Of Cell Population Proliferation Adenine Transport B Cell Differentiation Erythrocyte Differentiation Regulation Of Mitochondrial Membrane Permeability Adenine Nucleotide Transport Transmembrane Transport Mitochondrial ADP Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitophagy Proton Transmembrane Transport Mitochondrial ATP Transmembrane Transport Cellular Response To Leukemia Inhibitory Factor Adaptive Thermogenesis	Ubiquitin-dependent Protein Catabolic Process Endosome Organization Protein Ubiquitination Regulation Of Type I Interferon Production Negative Regulation Of Defense Response To Virus Protein K11-linked Ubiquitination Protein Localization To Perinuclear Region Of Cytoplasm
Pathways		Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Mitochondrial protein degradation
Drugs		Clodronic acid Etidronic acid
Diseases
GWAS			Platelet count ( 32888494) Refractive error ( 32231278)
Interacting Genes		6 interacting genes: CEBPA CKMT1B DUX4 NFKBIA PTEN RNF26	54 interacting genes: ASCC3 CAPN15 CBR1 CCDC50 CTNND1 DDB1 DNAJC13 DOCK7 EEF1G EPS15 GMPS GSR GSTP1 HNRNPF HNRNPK HRNR HSPA5 HSPA8 HSPA9 IMMT INCA1 KEAP1 KRT1 KRT10 KRT2 KRT5 KRT6C MAP7D2 MYO6 PARP10 PRSS1 RBCK1 RCC2 RNF31 RPS27A SHARPIN SLC25A5 SQSTM1 TAX1BP1 TOLLIP TOM1L2 TUBA1B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2Q1 UBE2U UBE2W USP15 WRNIP1 YME1L1
Entrez ID		292	79102
HPRD ID		02147	05842
Ensembl ID		ENSG00000005022	ENSG00000173456
Uniprot IDs		P05141 Q6NVC0	Q9BY78
PDB IDs
Enriched GO Terms of Interacting Partners?		Notch Signaling Pathway Regulation Of Osteoblast Differentiation Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Positive Regulation Of RNA Biosynthetic Process Response To Tumor Necrosis Factor Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle Regulation Of Cell Population Proliferation Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Cell Differentiation Positive Regulation Of DNA-templated Transcription Cellular Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Vitamin B2 C/EBP Complex Positive Regulation Of Transcription By RNA Polymerase II I-kappaB/NF-kappaB Complex Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Proteolysis Negative Regulation Of Cell Population Proliferation Regulation Of Defense Response Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Development White Fat Cell Proliferation Positive Regulation Of RNA Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Inflammatory Response Rb-E2F Complex Phosphocreatine Biosynthetic Process Creatine Kinase Activity Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Developmental Maturation Intracellular Signaling Cassette Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Phenylpropanoid Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly	Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Ubiquitination Post-translational Protein Modification Protein Modification By Small Protein Conjugation Proteolysis Involved In Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Modification Process Proteolysis Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Macromolecule Catabolic Process Ubiquitin-protein Transferase Activity Extracellular Exosome Protein K48-linked Ubiquitination Ubiquitin Protein Ligase Binding Protein Catabolic Process Ubiquitin Binding Keratinization LUBAC Complex Cytosol Macromolecule Metabolic Process Catabolic Process Proteasomal Protein Catabolic Process Nucleotide Binding ATP Binding Protein Linear Polyubiquitination Structural Constituent Of Skin Epidermis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intermediate Filament Organization Protein-macromolecule Adaptor Activity Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoplasm Peptide Cross-linking Protein Monoubiquitination Cornified Envelope Cellular Response To Interleukin-4 Regulation Of Canonical NF-kappaB Signal Transduction K63-linked Polyubiquitin Modification-dependent Protein Binding Protein Refolding Cellular Response To Stress Epidermis Development Response To Interleukin-4 Negative Regulation Of Signal Transduction Negative Regulation Of Programmed Cell Death Autophagosome Response To Stress Negative Regulation Of Fibroblast Proliferation
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