SLC25A5 and CKMT1B

Number of citations of the paper that reports this interaction (PMID 11602586)
17

Data Source:
HPRD (in vivo)

		SLC25A5	CKMT1B
Gene Name		solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	creatine kinase, mitochondrial 1B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Integral Component Of Plasma Membrane Membrane Mitochondrial Nucleoid Extracellular Vesicular Exosome MMXD Complex	Mitochondrion Mitochondrial Inner Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Adenine Transmembrane Transporter Activity Poly(A) RNA Binding	Creatine Kinase Activity ATP Binding
	Biological Process	Energy Reserve Metabolic Process Transport Chromosome Segregation Positive Regulation Of Cell Proliferation Adenine Transport Viral Process Small Molecule Metabolic Process Regulation Of Insulin Secretion Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway	Creatine Metabolic Process Phosphorylation Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process
Pathways		Integration of energy metabolism Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization HIV Infection Regulation of insulin secretion Host Interactions of HIV factors Interactions of Vpr with host cellular proteins	Metabolism of amino acids and derivatives Creatine metabolism
Drugs		Clodronate	Creatine
Diseases
GWAS
Protein-Protein Interactions		2 interactors: CKMT1B NFKBIA	3 interactors: CALM1 SLC25A5 VDAC1
Entrez ID		292	1159
HPRD ID		02147	00424
Ensembl ID		ENSG00000005022	ENSG00000237289
Uniprot IDs		P05141 Q6NVC0	P12532
PDB IDs			1QK1
Enriched GO Terms of Interacting Partners?		Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Nucleotide-binding Oligomerization Domain Containing 2 Signaling Pathway Cytoplasmic Sequestering Of NF-kappaB Cellular Response To Cold Creatine Metabolic Process Negative Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of NF-kappaB Import Into Nucleus Positive Regulation Of Cholesterol Efflux Response To Muramyl Dipeptide Negative Regulation Of Lipid Storage Positive Regulation Of Cholesterol Transport Cytoplasmic Sequestering Of Transcription Factor Regulation Of Cholesterol Efflux Cytoplasmic Sequestering Of Protein Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Protein Import Into Nucleus, Translocation Negative Regulation Of Notch Signaling Pathway Lipopolysaccharide-mediated Signaling Pathway Regulation Of Cholesterol Transport Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of NF-kappaB Import Into Nucleus Regulation Of Macrophage Derived Foam Cell Differentiation Negative Regulation Of DNA Binding Negative Regulation Of Transcription Factor Import Into Nucleus Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Response To Exogenous DsRNA Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Response To Cold Regulation Of Lipid Storage Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Lipid Transport Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Notch Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Negative Regulation Of NF-kappaB Transcription Factor Activity MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Negative Regulation Of Protein Import Into Nucleus MyD88-dependent Toll-like Receptor Signaling Pathway Response To DsRNA Positive Regulation Of Type I Interferon Production Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Myeloid Cell Differentiation Regulation Of DNA Binding Negative Regulation Of Intracellular Protein Transport Regulation Of Transcription Factor Import Into Nucleus	Energy Reserve Metabolic Process Adenine Transport Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Energy Derivation By Oxidation Of Organic Compounds Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of High Voltage-gated Calcium Channel Activity Purine Nucleobase Transport Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Nucleobase Transport Negative Regulation Of Transport Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Generation Of Precursor Metabolites And Energy Regulation Of Ion Transmembrane Transport Regulation Of Intracellular Transport Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Detection Of Calcium Ion Regulation Of Cell Communication By Electrical Coupling Viral Process Positive Regulation Of Phosphoprotein Phosphatase Activity Synaptic Transmission Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation Regulation Of Ion Transport Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Glycogen Catabolic Process Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Peptidyl-threonine Phosphorylation Regulation Of Voltage-gated Calcium Channel Activity Positive Regulation Of Protein Dephosphorylation Negative Regulation Of Cation Channel Activity Polysaccharide Catabolic Process Positive Regulation Of Monooxygenase Activity Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Positive Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Rhodopsin Mediated Signaling Pathway Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Activation Of Adenylate Cyclase Activity Nitric Oxide Metabolic Process Regulation Of Protein Autophosphorylation Reactive Nitrogen Species Metabolic Process Rhodopsin Mediated Signaling Pathway Cellular Carbohydrate Catabolic Process Positive Regulation Of Phosphatase Activity Response To Corticosterone Negative Regulation Of Mitochondrion Organization Positive Regulation Of Cation Channel Activity Response To Amphetamine Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway
Tagcloud ?		amongst amplified assist bcl2a1 birc5 cancerous casp3 ccnd2 cdc6 cdh1 comprising cumulation dissection dsp epha2 hcc hepatectomy krt18 lcm lymph microdissection mmp13 mmp2 node pdgfra ptpn2 rfc4 t7 vim
Tagcloud (Difference) ?		amongst amplified assist bcl2a1 birc5 cancerous casp3 ccnd2 cdc6 cdh1 comprising cumulation dissection dsp epha2 hcc hepatectomy krt18 lcm lymph microdissection mmp13 mmp2 node pdgfra ptpn2 rfc4 t7 vim
Tagcloud (Intersection) ?