SLC25A5

Description		solute carrier family 25 member 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Permeability Transition Pore Complex Plasma Membrane Membrane Mitochondrial Nucleoid MMXD Complex
	Molecular Function	Adenine Nucleotide Transmembrane Transporter Activity RNA Binding ATP:ADP Antiporter Activity Protein Binding Proton Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Antiporter Activity Oxidative Phosphorylation Uncoupler Activity Ubiquitin Protein Ligase Binding
	Biological Process	Chromosome Segregation Positive Regulation Of Cell Population Proliferation Adenine Transport B Cell Differentiation Erythrocyte Differentiation Regulation Of Mitochondrial Membrane Permeability Adenine Nucleotide Transport Transmembrane Transport Mitochondrial ADP Transmembrane Transport Negative Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitophagy Proton Transmembrane Transport Mitochondrial ATP Transmembrane Transport Cellular Response To Leukemia Inhibitory Factor Adaptive Thermogenesis
Pathways		Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane Mitochondrial protein degradation
Drugs		Clodronic acid Etidronic acid
Diseases
GWAS
Interacting Genes		6 interacting genes: CEBPA CKMT1B DUX4 NFKBIA PTEN RNF26
Entrez ID		292
HPRD ID		02147
Ensembl ID		ENSG00000005022
Uniprot IDs		P05141 Q6NVC0
PDB IDs
Enriched GO Terms of Interacting Partners?		Notch Signaling Pathway Regulation Of Osteoblast Differentiation Positive Regulation Of DNA-templated Transcription Initiation CHOP-C/EBP Complex Positive Regulation Of RNA Biosynthetic Process Response To Tumor Necrosis Factor Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Cell Cycle Regulation Of Cell Population Proliferation Regulation Of DNA-templated Transcription Initiation Negative Regulation Of Cell Differentiation Positive Regulation Of DNA-templated Transcription Cellular Response To Tumor Necrosis Factor RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Vitamin B2 C/EBP Complex Positive Regulation Of Transcription By RNA Polymerase II I-kappaB/NF-kappaB Complex Negative Regulation Of Synaptic Vesicle Clustering Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Central Nervous System Myelin Maintenance Rhythmic Synaptic Transmission Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Proteolysis Negative Regulation Of Cell Population Proliferation Regulation Of Defense Response Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Development White Fat Cell Proliferation Positive Regulation Of RNA Metabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Positive Regulation Of Inflammatory Response Rb-E2F Complex Phosphocreatine Biosynthetic Process Creatine Kinase Activity Nucleotide-binding Oligomerization Domain Containing 1 Signaling Pathway Phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase Activity Myelin Sheath Adaxonal Region Regulation Of Synaptic Vesicle Clustering Negative Regulation Of Wound Healing, Spreading Of Epidermal Cells Phosphatidylinositol Phosphate Phosphatase Activity Developmental Maturation Intracellular Signaling Cassette Positive Regulation Of Nucleobase-containing Compound Metabolic Process Response To Phenylpropanoid Negative Regulation Of Peptidyl-serine Phosphorylation Postsynaptic Density Assembly
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