RNF26 and TOM1L2

Number of citations of the paper that reports this interaction (PubMedID 37519262)
92

Data Source:
BioGRID (pull down)

		RNF26	TOM1L2
Description		ring finger protein 26	target of myb1 like 2 membrane trafficking protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane	Endosome Membrane Extracellular Exosome
	Molecular Function	Protein Binding Zinc Ion Binding Transferase Activity Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding Protein Kinase Binding Clathrin Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Endosome Organization Protein Ubiquitination Regulation Of Type I Interferon Production Negative Regulation Of Defense Response To Virus Protein K11-linked Ubiquitination Protein Localization To Perinuclear Region Of Cytoplasm	Signal Transduction Protein Transport Negative Regulation Of Mitotic Nuclear Division
Pathways
Drugs
Diseases
GWAS		Platelet count ( 32888494) Refractive error ( 32231278)	Hip index ( 34021172) Schizophrenia ( 25056061 28991256 29483656) TB-LM or TBLH-BMD (pleiotropy) ( 28743860) Total body bone mineral density ( 29304378) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		54 interacting genes: ASCC3 CAPN15 CBR1 CCDC50 CTNND1 DDB1 DNAJC13 DOCK7 EEF1G EPS15 GMPS GSR GSTP1 HNRNPF HNRNPK HRNR HSPA5 HSPA8 HSPA9 IMMT INCA1 KEAP1 KRT1 KRT10 KRT2 KRT5 KRT6C MAP7D2 MYO6 PARP10 PRSS1 RBCK1 RCC2 RNF31 RPS27A SHARPIN SLC25A5 SQSTM1 TAX1BP1 TOLLIP TOM1L2 TUBA1B UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2G2 UBE2Q1 UBE2U UBE2W USP15 WRNIP1 YME1L1	15 interacting genes: APP BBS4 BBS5 BBS9 FAM9B LAPTM5 MAP3K1 MYO6 NEDD4 RNF11 RNF26 SMURF1 UBC WBP2 WWP2
Entrez ID		79102	146691
HPRD ID		05842	18213
Ensembl ID		ENSG00000173456	ENSG00000175662
Uniprot IDs		Q9BY78	B7Z2U2 B7Z671 F5H3S6 Q6ZVM7
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein Polyubiquitination Protein Ubiquitination Post-translational Protein Modification Protein Modification By Small Protein Conjugation Proteolysis Involved In Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Modification Process Proteolysis Protein Metabolic Process Ubiquitin-dependent Protein Catabolic Process Macromolecule Catabolic Process Ubiquitin-protein Transferase Activity Extracellular Exosome Protein K48-linked Ubiquitination Ubiquitin Protein Ligase Binding Protein Catabolic Process Ubiquitin Binding Keratinization LUBAC Complex Cytosol Macromolecule Metabolic Process Catabolic Process Proteasomal Protein Catabolic Process Nucleotide Binding ATP Binding Protein Linear Polyubiquitination Structural Constituent Of Skin Epidermis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intermediate Filament Organization Protein-macromolecule Adaptor Activity Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoplasm Peptide Cross-linking Protein Monoubiquitination Cornified Envelope Cellular Response To Interleukin-4 Regulation Of Canonical NF-kappaB Signal Transduction K63-linked Polyubiquitin Modification-dependent Protein Binding Protein Refolding Cellular Response To Stress Epidermis Development Response To Interleukin-4 Negative Regulation Of Signal Transduction Negative Regulation Of Programmed Cell Death Autophagosome Response To Stress Negative Regulation Of Fibroblast Proliferation	BBSome Establishment Of Protein Localization Ciliary Membrane Modification-dependent Protein Catabolic Process Establishment Of Protein Localization To Vacuole Ubiquitin Protein Ligase Activity Potassium Channel Inhibitor Activity Protein Targeting To Vacuole Protein Ubiquitination Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Transport Protein Localization To Vacuole Receptor Catabolic Process Establishment Of Melanosome Localization Pericentriolar Material Melanosome Transport Pigment Granule Transport Ubiquitin Ligase Complex Post-translational Protein Modification Protein Polyubiquitination Negative Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of Catabolic Process Pigment Granule Localization Melanosome Localization Ubiquitin-dependent Protein Catabolic Process Centriolar Satellite Intracellular Protein Localization Protein Targeting To Lysosome Negative Regulation Of Potassium Ion Transport Establishment Of Protein Localization To Organelle Ciliary Transition Zone Protein Localization To Organelle Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Minus-end Directed Microfilament Motor Activity Macromolecule Catabolic Process Vacuolar Transport Formation Of Structure Involved In A Symbiotic Process Induction Of Programmed Cell Death Negative Regulation Of Pre-B Cell Receptor Expression Positive Regulation Of Lysosomal Membrane Permeability Engulfment Of Target By Autophagosome Fructose:sodium Symporter Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?