KLF15 and ZNF76

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KLF15	ZNF76
Description		KLF transcription factor 15	zinc finger protein 76
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nuclear Speck	Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Intracellular Glucose Homeostasis Regulation Of Transcription By RNA Polymerase II Glial Cell Differentiation Regulation Of Gene Expression Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Wnt Signaling Pathway Response To Insulin Negative Regulation Of Collagen Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of D-glucose Import Negative Regulation Of Transforming Growth Factor Beta Production Podocyte Differentiation Cellular Response To Endothelin Negative Regulation Of Peptidyl-lysine Acetylation	Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase II
Pathways		BMAL1:CLOCK,NPAS2 activates circadian expression
Drugs
Diseases
GWAS		Macular telangiectasia type 2 ( 28250457) Male-pattern baldness ( 28196072) Manganese levels ( 26025379) Metabolite levels ( 23378610) Refractive error ( 32231278) Urate levels ( 31578528)	Height ( 18391951 25282103 31562340) Plateletcrit ( 32888494) Refractive error ( 32231278)
Interacting Genes		24 interacting genes: AIRIM ANKS1A APPL1 BANP C11orf68 CCDC57 CRK DVL3 HNRNPF KBTBD7 NFYC NRF1 PIK3R3 POLR1C PRKAB2 SCNM1 SHFL SNX13 STAT3 SUV39H1 TCF21 ZBTB24 ZNF330 ZNF76	93 interacting genes: ACAT2 ALOXE3 ANKRD37 ANTKMT ATP5PO BLZF1 BOLA2 BOLA2B C10orf55 C22orf15 C3orf36 CCDC33 CEACAM6 CEP76 CSN3 DDIT4L DISC1 ENKD1 EP300 EXOSC1 FAM228A FAM90A1 FCRL4 FNDC8 FSD2 GIMAP6 GRAPL HDAC1 HOMEZ HUNK IKZF3 KCTD9 KLF15 KPNA3 KRT40 KRT75 L3MBTL3 LAP3 LETM1 LHX3 LHX4 LHX6 LIN37 LIN54 LMO1 MAGEA6 MBD3L1 MBD5 MED19 MFAP1 MORN3 MRPL12 MTFR1L MTUS2 MYL10 NEDD9 NRIP2 PIAS1 PMPCA POGZ PRKAR1B RAB3IP RALY REL RNF214 RPRD1A RPS21 SCNM1 SLAIN1 SMAD1 SNAI2 SPANXN3 SPATA8 SPMIP10 STMN3 TASOR2 TBC1D22B TBP TEKT5 TGS1 TNNI1 USP54 USP6 USP7 VXN WDR83 YPEL3 ZC2HC1C ZC4H2 ZMYM6 ZNF420 ZNF526 ZNF623
Entrez ID		28999	7629
HPRD ID		07568	01929
Ensembl ID		ENSG00000163884	ENSG00000065029
Uniprot IDs		Q9UIH9	P36508
PDB IDs		2ENT
Enriched GO Terms of Interacting Partners?			Protein Binding Medial Motor Column Neuron Differentiation
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