KLF15 and C11orf68

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KLF15	C11orf68
Description		KLF transcription factor 15	chromosome 11 open reading frame 68
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Nuclear Speck
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Protein Binding
	Biological Process	Intracellular Glucose Homeostasis Regulation Of Transcription By RNA Polymerase II Glial Cell Differentiation Regulation Of Gene Expression Cardiac Muscle Hypertrophy In Response To Stress Regulation Of Wnt Signaling Pathway Response To Insulin Negative Regulation Of Collagen Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of D-glucose Import Negative Regulation Of Transforming Growth Factor Beta Production Podocyte Differentiation Cellular Response To Endothelin Negative Regulation Of Peptidyl-lysine Acetylation
Pathways		BMAL1:CLOCK,NPAS2 activates circadian expression
Drugs
Diseases
GWAS		Macular telangiectasia type 2 ( 28250457) Male-pattern baldness ( 28196072) Manganese levels ( 26025379) Metabolite levels ( 23378610) Refractive error ( 32231278) Urate levels ( 31578528)	Acne (severe) ( 24927181) Asthma ( 31959851)
Interacting Genes		24 interacting genes: AIRIM ANKS1A APPL1 BANP C11orf68 CCDC57 CRK DVL3 HNRNPF KBTBD7 NFYC NRF1 PIK3R3 POLR1C PRKAB2 SCNM1 SHFL SNX13 STAT3 SUV39H1 TCF21 ZBTB24 ZNF330 ZNF76	14 interacting genes: CSDE1 EIF4H KCNE3 KLF15 MEOX2 MTCL1 NONO PHETA1 REL SDCBP SH3GL3 TRAPPC2L ZNF341 ZNF512B
Entrez ID		28999	83638
HPRD ID		07568	12553
Ensembl ID		ENSG00000163884	ENSG00000175573
Uniprot IDs		Q9UIH9	Q9H3H3
PDB IDs		2ENT	1ZTP 2Q4K
Enriched GO Terms of Interacting Partners?
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