TPRN and MYO15B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TPRN	MYO15B
Description		taperin	myosin XVB
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microvillus Stereocilium Cell Projection Stereocilium Base
	Molecular Function	Actin Binding Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase 1 Binding Phosphatase Binding Protein Phosphatase Binding
	Biological Process	Sensory Perception Of Sound Auditory Receptor Cell Stereocilium Organization Stereocilium Maintenance
Pathways		Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Interacting Genes		9 interacting genes: CLIC1 CLIC2 CLIC4 CLIC5 EPS8 MYO15B PPP1CA PPP1CC WHRN	96 interacting genes: ABI2 ADAMTSL4 BEND7 C7orf57 CARD9 CCNC CEP57L1 CFAP68 COIL CRX DNAJA3 DUSP21 ERAS FAM9B FHL2 GAB2 GADD45GIP1 GFAP GINS3 GPRASP3 HOXA1 IHO1 IKZF3 KATNBL1 KCNJ6 KIAA0408 KIF24 KIFC3 KLF4 KLHL12 KRT13 KRT31 KRT34 KRT35 KRT75 LIMS1 MTUS2 MYOZ3 NADSYN1 NBPF19 NDUFA12 NECAB2 NEDD4 NEFL NHSL2 NKAPD1 NOTCH2NLA NR1D2 NUP62 PAK5 PKNOX2 PLEKHA3 PNMA1 PNMA5 POU6F2 PPM1K PRKAR1B RAD54B RBM11 RCN1 RCN3 REL RPH3AL RUNDC3A SAXO4 SLA SORBS3 SPATC1L SPRED2 SSBP4 TCF12 TCF4 TEX13A TFIP11 TLE5 TPRN TRAF2 TRIM14 TRIM27 TRIM29 TRIM54 TSC22D4 UBQLN2 VGLL3 ZBED1 ZBTB10 ZBTB3 ZBTB32 ZBTB8A ZCCHC14 ZMAT1 ZNF114 ZNF438 ZNF774 ZNF837 ZNRD2
Entrez ID		286262	80022
HPRD ID		12977
Ensembl ID		ENSG00000176058	ENSG00000266714
Uniprot IDs		Q4KMQ1	Q96JP2 Q9H614
PDB IDs		6Y9Q	2DLP
Enriched GO Terms of Interacting Partners?		Chloride Channel Complex Chloride Channel Activity Chloride Transmembrane Transport Chloride Transport Inorganic Anion Transmembrane Transport Monoatomic Ion Channel Complex Monoatomic Anion Transmembrane Transport Inorganic Anion Transport Monoatomic Anion Transport Stereocilium PTW/PP1 Phosphatase Complex Stereocilium Bundle Stereocilium Tip Entrainment Of Circadian Clock By Photoperiod Protein Phosphatase 1 Binding Photoperiodism Entrainment Of Circadian Clock Oxidoreductase Activity Inorganic Ion Transmembrane Transport Monoatomic Ion Transmembrane Transport Brush Border Glycogen Metabolic Process Circadian Regulation Of Gene Expression Energy Reserve Metabolic Process Polysaccharide Metabolic Process Phosphatase Activity Monoatomic Ion Transport Protein Dephosphorylation Protein Serine/threonine Phosphatase Activity RNA Polymerase II CTD Heptapeptide Repeat S5 Phosphatase Activity Cerebellar Purkinje Cell Layer Formation Paranodal Junction Maintenance Regulation Of Circadian Rhythm Positive Regulation Of Termination Of RNA Polymerase II Transcription, Poly(A)-coupled Stereocilia Ankle Link USH2 Complex Extracellular Exosome Plasma Membrane Transmembrane Transport Regulation Of Protein-containing Complex Disassembly Positive Regulation Of Termination Of DNA-templated Transcription Dephosphorylation Positive Regulation Of Termination Of RNA Polymerase II Transcription Branching Morphogenesis Of An Epithelial Tube Circadian Rhythm Phosphoprotein Phosphatase Activity Growth Cone Glutamatergic Synapse Dendritic Spine Stereocilia Ankle Link Complex	Identical Protein Binding Intermediate Filament Organization Protein Binding Intermediate Filament-based Process Intermediate Filament Cytoskeleton Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Supramolecular Fiber Organization Structural Constituent Of Skin Epidermis Intermediate Filament Negative Regulation Of G Protein-coupled Receptor Internalization Regulation Of RNA Metabolic Process Zinc Ion Binding Regulation Of Nucleobase-containing Compound Metabolic Process Keratin Filament DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Axonemal A Tubule Inner Sheath RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA Binding
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