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MLNR and GHRL
Number of citations of the paper that reports this interaction (PMID
12606621
)
9
Data Source:
HPRD
(in vitro)
MLNR
GHRL
Gene Name
motilin receptor
ghrelin/obestatin prepropeptide
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Extracellular Region
Extracellular Space
Endoplasmic Reticulum Lumen
Axon
Secretory Granule Lumen
Molecular Function
G-protein Coupled Receptor Activity
Growth Hormone-releasing Hormone Receptor Activity
G-protein Coupled Receptor Binding
Growth Hormone-releasing Hormone Activity
Protein Tyrosine Kinase Activator Activity
Ghrelin Receptor Binding
Biological Process
G-protein Coupled Receptor Signaling Pathway
Digestion
Activation Of MAPK Activity
Gastric Acid Secretion
Negative Regulation Of Endothelial Cell Proliferation
Glucose Metabolic Process
G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Cytosolic Calcium Ion Concentration
Actin Polymerization Or Depolymerization
Adult Feeding Behavior
Response To Hormone
Hormone-mediated Signaling Pathway
Dendrite Development
Negative Regulation Of Angiogenesis
Growth Hormone Secretion
Positive Regulation Of Insulin Secretion
Regulation Of Response To Food
Positive Regulation Of Appetite
Negative Regulation Of Interleukin-1 Beta Production
Negative Regulation Of Locomotion
Positive Regulation Of Multicellular Organism Growth
Regulation Of Cell Proliferation
Negative Regulation Of Circadian Sleep/wake Cycle, REM Sleep
Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process
Negative Regulation Of Apoptotic Process
Cortisol Secretion
Response To Estrogen
Cellular Protein Metabolic Process
Negative Regulation Of Interleukin-6 Biosynthetic Process
Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
Negative Regulation Of Insulin Secretion
Decidualization
Negative Regulation Of Inflammatory Response
Cartilage Development
Positive Regulation Of Corticotropin Secretion
Positive Regulation Of Cortisol Secretion
Positive Regulation Of Synapse Assembly
Regulation Of Excitatory Postsynaptic Membrane Potential
Positive Regulation Of Growth Hormone Secretion
Positive Regulation Of Growth Hormone Receptor Signaling Pathway
Positive Regulation Of Protein Tyrosine Kinase Activity
Pathways
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
G alpha (q) signalling events
G alpha (q) signalling events
Signaling by GPCR
GPCR downstream signaling
Peptide ligand-binding receptors
Gastrin-CREB signalling pathway via PKC and MAPK
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
GHRHR
GHRL
GPRASP1
MLN
8 interactors:
ACE2
AGRP
GHRHR
GHSR
LEP
MLNR
NPY
UBQLN1
Entrez ID
2862
51738
HPRD ID
04197
05638
Ensembl ID
ENSG00000102539
ENSG00000157017
Uniprot IDs
O43193
Q9UBU3
PDB IDs
1P7X
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of Growth Hormone Secretion
Regulation Of Growth Hormone Secretion
Growth Hormone Secretion
Positive Regulation Of Multicellular Organism Growth
Peptide Hormone Secretion
Peptide Secretion
Positive Regulation Of Peptide Hormone Secretion
Positive Regulation Of Peptide Secretion
Hormone Secretion
Hormone Transport
Peptide Transport
Regulation Of Multicellular Organism Growth
Positive Regulation Of Hormone Secretion
Cortisol Secretion
Amide Transport
Cell-cell Signaling
Positive Regulation Of Developmental Growth
Somatotropin Secreting Cell Development
Negative Regulation Of Circadian Sleep/wake Cycle, REM Sleep
G-protein Coupled Receptor Catabolic Process
G-protein Coupled Receptor Signaling Pathway
Response To Estrogen
Positive Regulation Of Growth Hormone Receptor Signaling Pathway
Positive Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
Regulation Of Peptide Hormone Secretion
Positive Regulation Of Growth
Positive Regulation Of Cortisol Secretion
Positive Regulation Of Corticotropin Secretion
Positive Regulation Of Appetite
Regulation Of Hormone Secretion
Regulation Of Hormone Levels
Regulation Of Corticotropin Secretion
Regulation Of Growth Hormone Receptor Signaling Pathway
Negative Regulation Of Tumor Necrosis Factor Biosynthetic Process
Somatotropin Secreting Cell Differentiation
Regulation Of Developmental Growth
Negative Regulation Of Circadian Sleep/wake Cycle, Sleep
Regulation Of Circadian Sleep/wake Cycle, REM Sleep
Negative Regulation Of Interleukin-6 Biosynthetic Process
Positive Regulation Of Secretion
Regulation Of Circadian Sleep/wake Cycle, Non-REM Sleep
Adult Feeding Behavior
Gastric Acid Secretion
Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Establishment Of Localization In Cell
Response To Steroid Hormone
Adenohypophysis Development
Negative Regulation Of Interleukin-1 Beta Production
Secretion By Cell
Regulation Of Circadian Sleep/wake Cycle, Sleep
Adult Feeding Behavior
Feeding Behavior
Regulation Of Response To Food
Regulation Of Appetite
Adult Behavior
Behavior
Female Pregnancy
Positive Regulation Of Appetite
Regulation Of Hormone Levels
Peptide Hormone Secretion
Peptide Secretion
Response To Insulin
Maternal Process Involved In Female Pregnancy
Multicellular Organismal Reproductive Process
Hormone Secretion
Multicellular Organism Reproduction
Hormone Transport
Peptide Transport
Growth Hormone Secretion
Digestion
Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Reproduction
Single-organism Behavior
Response To Peptide Hormone
Amide Transport
Response To Peptide
G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Developmental Growth
Regulation Of Blood Pressure
Cellular Response To Hormone Stimulus
Hormone Metabolic Process
Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway
Reproductive Process
Regulation Of Peptide Hormone Secretion
Eating Behavior
Positive Regulation Of Growth
Regulation Of Hormone Secretion
Negative Regulation Of Peptide Secretion
Response To Organonitrogen Compound
Regulation Of Developmental Growth
Cell Surface Receptor Signaling Pathway
Blood Circulation
Cell-cell Signaling
Positive Regulation Of Multicellular Organism Growth
Response To Hormone
Regulation Of Vasoconstriction
Negative Regulation Of Hormone Secretion
Response To Stimulus
Regulation Of Protein Metabolic Process
Response To Nutrient Levels
Tagcloud
?
breeding
broiler
bw
bw49
bw70
bwg
chickens
desorption
fcr
feed
fi
flight
genotyped
ghrelin
ghsr
haplotypes
igf1r
maldi
meanwhile
rs14011776
rs14011780
rs14011783
rs14678932
rs14986828
rs15675065
rs15675067
rs16675844
snps
yellow
Tagcloud (Difference)
?
breeding
broiler
bw
bw49
bw70
bwg
chickens
desorption
fcr
feed
fi
flight
genotyped
ghrelin
ghsr
haplotypes
igf1r
maldi
meanwhile
rs14011776
rs14011780
rs14011783
rs14678932
rs14986828
rs15675065
rs15675067
rs16675844
snps
yellow
Tagcloud (Intersection)
?