TPRG1 and CIDEB

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TPRG1	CIDEB
Description		tumor protein p63 regulated 1	cell death inducing DFFA like effector b
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Lipid Droplet Cytosol Membrane COPII Vesicle Coat COPI-coated Vesicle Cytoplasmic Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Molecular Adaptor Activity Phosphatidic Acid Binding Lipid Transfer Activity
	Biological Process		Apoptotic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Lipid Storage Response To Nutrient Levels Very-low-density Lipoprotein Particle Assembly Positive Regulation Of Apoptotic Process COPII-coated Vesicle Cargo Loading Regulation Of Triglyceride Metabolic Process Execution Phase Of Apoptosis Intermembrane Lipid Transfer Lipid Droplet Fusion
Pathways
Drugs
Diseases
GWAS		Allergic rhinitis ( 30013184) Asthma ( 31959851) Axial length ( 24144296) Cutaneous squamous cell carcinoma ( 32041948) Femur bone mineral density x serum urate levels interaction ( 34046847) Hair color ( 26926045) Squamous cell carcinoma ( 26829030)	Anorectal malformation ( 31136621) Height ( 28552196) Parent of origin effect on language impairment (paternal) ( 24571439)
Interacting Genes		19 interacting genes: APOC1 APOC2 APOC4 AQP6 CGRRF1 CIDEB EBAG9 FCER1G HSD17B11 HSD17B13 REEP4 RETREG3 RHBDD2 SCN3B SLC10A6 SLC35H1 SLC71A2 TMEM120A TMX2	68 interacting genes: ABHD16A AFG1L APOC1 ARL8B ATP5ME ATP5MJ BCL2L2 CAND2 CIDEA CLCN1 CMPK1 COL10A1 COL8A1 COX7C DFFA DFFB DHRSX DNAJA3 FAM218A FAM47E-STBD1 FKBP8 FOXD4L3 FUNDC2 GCSH GNB3 GPAM H4C7 HAPLN2 HCCS HIGD1C IRX2-DT MEST MICOS10 MPC2 MRPL36 MRPL57 MTERF4 NAALAD2 NDRG4 NFU1 NME4 PBX3 PDHX PGLYRP3 PISD PPIF RAMP2 RHBDD2 ROMO1 RTP5 SAA2 SAA4 SAR1B SCO1 SCO2 SDHAF1 SFXN1 SMARCC1 SPG21 TAOK2 TBX2 TEX44 THBD TIMM17B TMEM14B TPRG1 TSR1 UFSP1
Entrez ID		285386	27141
HPRD ID		13451	11981
Ensembl ID		ENSG00000188001	ENSG00000136305
Uniprot IDs		Q6ZUI0	Q9UHD4
PDB IDs			1D4B
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Very-low-density Lipoprotein Particle Steroid Dehydrogenase Activity Acylglycerol Homeostasis Negative Regulation Of Very-low-density Lipoprotein Particle Clearance Chylomicron Remnant Clearance Triglyceride-rich Lipoprotein Particle Clearance Triglyceride Homeostasis Regulation Of Triglyceride Metabolic Process Endoplasmic Reticulum Lipid Transport Regulation Of Phospholipid Catabolic Process Lipase Inhibitor Activity Organic Hydroxy Compound Transport Very-low-density Lipoprotein Particle Assembly Chylomicron Phospholipid Efflux Lipid Droplet Estradiol 17-beta-dehydrogenase [NAD(P)+] Activity Negative Regulation Of Lipoprotein Particle Clearance Negative Regulation Of Cholesterol Transport Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Plasma Lipoprotein Particle Assembly Protein-lipid Complex Assembly Regulation Of Lipid Metabolic Process Plasma Lipoprotein Particle Clearance Organophosphate Ester Transport Cholesterol Efflux Negative Regulation Of Receptor-mediated Endocytosis Lipoprotein Metabolic Process Lipid Storage Regulation Of Phospholipid Metabolic Process Plasma Lipoprotein Particle Remodeling Lipid Homeostasis Protein-containing Complex Remodeling Negative Regulation Of Lipid Transport Negative Regulation Of Phosphatidylcholine Catabolic Process Nitrate Transmembrane Transporter Activity Transmembrane Transport IgE Receptor Activity Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport Regulation Of Lipid Biosynthetic Process Regulation Of Fatty Acid Biosynthetic Process Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Regulation Of Lipid Catabolic Process Positive Regulation Of Very-low-density Lipoprotein Particle Remodeling PH-gated Chloride Channel Activity Nitrate Transmembrane Transport	Mitochondrion Mitochondrial Inner Membrane Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Apoptotic DNA Fragmentation High-density Lipoprotein Particle Protein Binding Mitochondrion Organization Mitochondrial Membrane Copper Chaperone Activity Disordered Domain Specific Binding T Cell Apoptotic Process Mitochondrial Matrix Organophosphate Biosynthetic Process Cytochrome Complex Assembly Pyruvate Decarboxylation To Acetyl-CoA Activation-induced Cell Death Of T Cells Mitochondrial Respiratory Chain Complex Assembly Lymphocyte Apoptotic Process Import Into The Mitochondrion Negative Regulation Of Execution Phase Of Apoptosis Protein Localization To Mitochondrion
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