ANGPT2 and ANXA7

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		ANGPT2	ANXA7
Gene Name		angiopoietin 2	annexin A7
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Plasma Membrane Cell Projection	Nucleus Nuclear Envelope Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Chromaffin Granule Membrane Extracellular Vesicular Exosome
	Molecular Function	Receptor Binding Protein Binding Receptor Tyrosine Kinase Binding Metal Ion Binding	Integrin Binding Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Poly(A) RNA Binding Calcium-dependent Protein Binding
	Biological Process	Angiogenesis Response To Hypoxia Signal Transduction Germ Cell Development Blood Coagulation Response To Radiation Response To Mechanical Stimulus Response To Glucose Negative Regulation Of Cell-substrate Adhesion Response To Organic Cyclic Compound Response To Activity Negative Regulation Of Angiogenesis Organ Regeneration Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Angiogenesis Tie Signaling Pathway Leukocyte Migration Negative Regulation Of Positive Chemotaxis Maternal Process Involved In Female Pregnancy Cellular Response To Growth Factor Stimulus Glomerulus Vasculature Development	Cellular Calcium Ion Homeostasis Autophagy Hemostasis Cell Proliferation Regulation Of Cell Shape Response To Salt Stress Cellular Water Homeostasis Negative Regulation Of Gene Expression Response To Organic Cyclic Compound Epithelial Cell Differentiation Social Behavior Response To Calcium Ion Membrane Fusion
Pathways		Tie2 Signaling Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: ANGPT1 ANXA7 CDKN1A CSNK2B TEK	108 interactors: A1BG A2M ACTB ACTL6B ADAMTS10 ANGPT2 APC APLP1 ATP5B ATP6V1A ATXN3 BAG6 C14orf1 CCDC90B CCT7 CDK4 CELF3 CENPB CHGB CLEC3B COL11A2 COL4A2 COL4A5 COPS6 CPNE2 CPNE6 CPSF3L CRMP1 CSAD CTSB DDAH2 DMPK DOCK7 DVL1 DYNC1I1 EEF1A1 EXT2 F13A1 FAF1 FBN3 FGB FLAD1 GAPDH GBP2 GDF9 GNB2 GNB5 HADHB HMGXB3 HOXD8 INPP5K KLHL23 KMT2B LRIF1 MED31 MPPED1 MSH2 NGFR NMT2 NPRL2 OTUB1 PAAF1 PAX8 PDCD6 PDHB PKM PLD3 PRKACA PRKCA PRKCB PRKCG PRKG1 PSMB10 QARS RBBP4 RBM48 RPA1 RPL13 RPS2 S100A10 SDF4 SEMA5B SETDB1 SMPD1 SP110 SRC SRI SUMO3 TAF5L TIAM2 TLE1 TMEM108 TMSB4X TP53 TRMT2A TUBA1A TUBB2B TUBB3 UBE2D1 UCHL5 UNC119 USP4 VIM WDR18 WDR73 ZBTB16 ZNF135 ZNF431
Entrez ID		285	310
HPRD ID		03563	01720
Ensembl ID		ENSG00000091879	ENSG00000138279
Uniprot IDs		O15123	B2R657 P20073
PDB IDs		1Z3S 1Z3U 2GY7 4JZC
Enriched GO Terms of Interacting Partners?		Tie Signaling Pathway Regulation Of Endothelial Cell Migration Regulation Of Cytokine Secretion Involved In Immune Response Regulation Of Epithelial Cell Migration Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Phosphorylation Regulation Of Protein Localization To Nucleus Regulation Of Kinase Activity Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Phosphorylation Negative Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Protein Modification Process Regulation Of Intracellular Protein Transport Regulation Of Vascular Permeability Regulation Of Protein Phosphorylation Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Phosphorylation Sprouting Angiogenesis Positive Regulation Of Endothelial Cell Migration Hemostasis Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Organ Regeneration Positive Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Protein Kinase B Signaling Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Transferase Activity Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Body Fluid Levels Regulation Of Cell Migration Regulation Of Protein Transport Regulation Of Cell Motility Regulation Of Peptidyl-serine Phosphorylation Regulation Of Macrophage Migration Inhibitory Factor Signaling Pathway Regulation Of Cellular Component Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Cellular Protein Metabolic Process Regulation Of Locomotion Regulation Of Cellular Component Movement Regulation Of Protein Kinase B Signaling Positive Regulation Of ERK1 And ERK2 Cascade	Anatomical Structure Development Multicellular Organismal Development Developmental Process System Development Cellular Metabolic Process Metabolic Process Cellular Response To Organic Substance Platelet Activation Regulation Of Protein Metabolic Process Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Regulation Of Cellular Protein Metabolic Process Blood Coagulation Response To Growth Factor Programmed Cell Death Hemostasis Negative Regulation Of Cellular Protein Metabolic Process Cell Death Catabolic Process Death Response To Organic Substance Apoptotic Process Histone H3-T6 Phosphorylation Regulation Of Apoptotic Process Nervous System Development Regulation Of Body Fluid Levels Negative Regulation Of Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Cellular Protein Metabolic Process Regulation Of Proteolysis Mitotic Cell Cycle Process Negative Regulation Of Glucose Transport Organelle Organization Cell Activation Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Catalytic Activity Cellular Process Regulation Of Cellular Response To Insulin Stimulus Wound Healing Cellular Response To Stimulus Regulation Of Proteasomal Protein Catabolic Process Gene Expression Protein Metabolic Process Mitotic Cell Cycle Organ Development Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Chromosome Organization
Tagcloud ?		clonality clones comings depicting deregulated engrafted gammaretroviral genotoxicity gv harboring hematopoiesis hsc hscs il2rg immunodeficient insertion insertional integrating integrations leukemogenesis ltr nsg overrepresentation resembling transplanted underscore utilizing vicinity	annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Difference) ?		clonality clones comings depicting deregulated engrafted gammaretroviral genotoxicity gv harboring hematopoiesis hsc hscs il2rg immunodeficient insertion insertional integrating integrations leukemogenesis ltr nsg overrepresentation resembling transplanted underscore utilizing vicinity	annexin anticancer antitumor chinese cytotoxic cytotoxicity decreasing depressed dramatically eecp ethanol exerted explored huvecs kappa mb mcf mda mitochondrial mu obviously p65 possess propolis ros umbilical upregulating vein
Tagcloud (Intersection) ?